Meta-analysis of Vitamin D

669 Meta-analyses

See also Overview Meta-analysis of Vitamin D
Unfortunately, a meta-analysis will frequently fail to consider one or more of the following

Dose size (Some gave the same importance to 40 IU as 10,000 IU)
Dose frequency (Some ignore differences between daily, weekly, monthly, and annual dosing)
Duration, (Some gave same importance to 4 weeks as 4 years)
It takes 3 to 12 months for vitamin D levels to come to a new plateau
and it often takes months for the body to then utilize it
Pre-existing Vitamin D blood level
adding vitamin D does not provide much benefit if person alrady has a good level
Cofactors (Most meta-analyses ignore the importance of Magnesium, Omega-3, Vitamin K2, etc)
Type of Vitamin D - D3 far better than D2
Those with poor guts need a different type of vitamin D
Those who are Obese need 2.5 X more vitamin D
Many drugs, such as statins deplete vitamin D or the Magnesium needed by Vitamin D
For some health problems pulsed vitamin D, not daily, is far better (gets over possible Vitamin D receptor limitation)

See also Proof that Vitamin D Works

See also All items in category Intervention Vitamin D 833 items

See also Clinical Trials of vitamin D can have “biological flaws” – Jan 2015
See also Nice description of Meta-Analysis in Scientific American Jan 2014
See also The Misuse of Meta-analysis in Nutrition Research JAMA Sept 2017
". . . they have mixed apples and oranges—and sometimes “apples, lice, and killer whales”—yielding meaningless conclusions"
"In a 2007 review of 111 industry-funded (nutrition) studies, funding source was significantly related to study conclusions"

VitaminDWiki Comment on Scientific American article

It does not mention the major problems of Vitamin D Meta-analyses.
1) Dose sizes are ignored: Studies assume benefit from 400 IU is the same as for 4,000 IU
2) Durations are ignored: Studies assume benefit of 1 month dosing is the same as 1 year dosing
3) Existing Vitamin D levels are often ignored.
Studies ignore that a 20 ng addition to a 10 ng person has vastly more benefit than a 20 ng addition to a 40 ng person
A rare example of a good meta-analysis is: one on depression - April 2014

Really great medical studies do not blindly give a single supplement/drug to a group, but rather treat the patients as individuals and provide extra Magnesium, Vitamin K2, Omega-3, Vitamin C, etc as needed. These studies, which have the best results, are not Random Controlled Trials and are virtually never included in a meta-analysis.

Likewise, the trials which give vitamin D to an entire country, or to all of the patients (immoral not to do so) are never considered by any meta-analysis

Vitamin D has climbed the pyramid for decades, but has not yet reached the top

Vitamin D Pyramid

International prospective register of on-going systematic reviews: 569 reviews of Vitamin D as of March 2020

PROSPERO

Intervention - Vitamin D includes the following:

Studies in VitaminDWiki

Year	Randomized Controlled Trials	Interventions	Meta- analyses
2022	900+	700+	600+
2017	-	48	52
2015	69	82	35
2012	41	38	39

Note: Govt recommendations in 2015 often ignored data after 2011

Vitamin D has climbed the pyramid for decades, but has not yet reached the top
International prospective register of on-going systematic reviews: 569 reviews of Vitamin D as of March 2020
VitaminDWiki - Vitamin D meta-analyses for different health problems
20 Most-visited pages in Meta-analysis category in VitaminDWiki
All of the articles in Meta-Analysis - sorted by date

VitaminDWiki - Vitamin D meta-analyses for different health problems

Number of Meta-analyses per health problem
ADHD7, Autism7, Autoimmune5, Back pain5, Bone -8, Breathing35, Cancer - Bladder5, Cancer - Breast24, Cancer - Colon25, Cancer - Liver4, Cancer - Lung7, Cancer - Lymphoma4, Cancer - Pancreatic4, Cancer - Prostate8, Cancer16, Cardiovascular38, Cognitive22, Depression16, Diabetes38, Falls and Fractures23, Fertility and sperm6, Genetics4, Gut9, Hypertension22, Infant-Child23, Inflammation11, Kidney12, Liver4, Metabolic Syndrome5, Mortality 28, Multiple Sclerosis13, Obesity8, Osteoarthritis4, Osteoporosis9, Pain - chronic5, Parkinson12, Pregnancy51, Psoriasis6, Rheumatoid Arthritis8, Seniors13, Skin8, Sleep4, Sports11, Stroke8, Thyroid and parathyroid5, Trauma and surgery19, Tuberculosis14, UV and Vitamin D4, Virus37, Vision6, Women7, Youth4

20 Most-visited pages in Meta-analysis category in VitaminDWiki

Id	Page	Hits	Last modification	Creator	Categories
9810	Dementia is associated with low vitamin D - many studies	238685	07 Jan, 2025 22:29	admin	Seniors Meta-analysis of Vitamin D Cognitive
9344	Thyroid Cancer 1.4 X higher risk if low vitamin D– meta-analysis Feb 2018	214655	04 Jul, 2024 16:41	admin	Meta-analysis of Vitamin D Cancer - Other
13263	Melanoma might be suppressed by Vitamin D - many studies	201732	21 Jun, 2024 20:41	admin	Cancer - Skin Meta-analysis of Vitamin D
15325	After COVID infection, Vitamin D helps - many studies	65290	27 Feb, 2025 18:07	admin	Meta-analysis of Vitamin D Intervention Virus
5913	Meta-analysis of Vitamin D	53004	13 Dec, 2023 16:12	admin	Meta-analysis of Vitamin D Evidence for D Category
7021	Overview Epileptic children and Vitamin D	52211	12 Jan, 2025 19:10	admin	Overviews Meta-analysis of Vitamin D Category Epilepsy
4267	Overview Meta-analysis of Vitamin D	47475	03 Jun, 2023 12:16	admin	Overviews Meta-analysis of Vitamin D Associations
15653	Diabetes and Vitamin D meta-analyses - many studies	39290	05 Nov, 2024 17:24	admin	Diabetes Meta-analysis of Vitamin D
8629	RCTs probably not the future gold standard - CDC former head – July 2017	37835	28 Mar, 2022 02:08	admin	Meta-analysis of Vitamin D Evidence for D Intervention
3265	Alzheimer's Disease more likely with low vitamin D – meta-analysis Oct 2012	37249	13 Dec, 2015 23:20	admin	Meta-analysis of Vitamin D Top news Cognitive
5252	Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014	31483	30 Apr, 2021 03:23	admin	Depression Meta-analysis of Vitamin D Top news
4808	Sports benefits from up to 50 ng of Vitamin – meta-analysis - Nov 2012	29591	30 May, 2021 18:10	admin	Sports and Vitamin D Meta-analysis of Vitamin D Optimum
8553	Overview of Vitamin D Meta-analysis and RCT for Caucasians - July 2017	27980	17 Aug, 2020 01:27	admin	Meta-analysis of Vitamin D Intervention Top news
5322	Cancer survival 4 percent more likely with just a little more vitamin D (4 ng) - meta-analysis July 2014	27219	06 Aug, 2024 17:17	admin	Mortality and D Cancer - Colon Cancer - Breast Cancer Meta-analysis of Vitamin D Cancer - Lymphoma
8315	Low Vitamin D results in adverse pregnancy and birth outcomes – Wagner meta-analysis March 2017	27033	19 Mar, 2017 02:09	admin	Pregnancy Meta-analysis of Vitamin D Infant-Child
11283	How to read a medical study (with notes on Vitamin D studies) – Oct 2019	26332	30 Oct, 2019 19:55	admin	Meta-analysis of Vitamin D Top news
4213	Vitamin D and Respiratory Tract Infections – meta-analysis with charts June 2013	24871	23 Jan, 2018 18:40	admin	Breathing Meta-analysis of Vitamin D Inflammation
10573	Diabetic Foot Ulcers helped by Vitamin D - meta-analyses many studies	24632	25 Jan, 2025 14:58	admin	Diabetes Meta-analysis of Vitamin D
7053	Chronic Widespread Pain associated with Vitamin D under 10 ng – meta-analysis Oct 2015	23684	12 Dec, 2015 00:28	admin	Pain - chronic Meta-analysis of Vitamin D
9058	The Misuse of Meta-analysis in Nutrition Research (and vitamin D) – JAMA Oct 2017	23602	04 Dec, 2017 22:02	admin	Meta-analysis of Vitamin D

All of the articles in Meta-Analysis - sorted by date

wiki page:

Short URL =https://is.gd/MetaD

Meta-analysis of Vitamin D

52502 visitors, last modified 13 Dec, 2023,

52502 visitors, last modified 13 Dec, 2023,

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Links to this page
- One pill every two weeks gives you all the vitamin D most adults need Consensus that treatment of Rickets by a single supplement took 80 years, how long for health problems needing 2 supplements – Feb 2016 VitaminDWiki Mega-Search (Interim Version) Major heart problems if have less than 15 ng of Vitamin D – Nov 2015 Overview Breast Cancer and Vitamin D Intervention - Vitamin D Vitamin D fights many health problems – an umbrella review of 508 studies – July 2022 MegaSearchOverview Criteria to associate a health problem with low vitamin D More than half of the FDA entire budget now comes from Big Pharma, not the govt. – Sept 2018 Do not expect a doctor to recommend a pill which will eliminate his job (vitamin D) Why many vitamin D trials fail to find benefits - Nov 2016 Breast Cancer again associated with low vitamin D – 15th meta-analysis Sept 2020 RCTs probably not the future gold standard - CDC former head – July 2017 VitaminDWiki had a booth at Vitamin D Workshop May 2019 Review of meta-analyses of non-skeletal benefits of vitamin D (Mortality, RTI, etc) – July 2017 Do not expect your doctor to know about vitamin D Evidence-Based Vitamin D Conference - Dec 2014 Overview of Vitamin D Meta-analysis and RCT for Caucasians - July 2017 Treatment by Vitamin D Vitamin D voting by panel – agreed upon bone health and high risk of chronic diseases – July 2016 Vitamin D publications and supplementation are increasing, need more studies – May 2018 Hand, Foot, and Mouth disease (virus) strongly associated with low vitamin D – May 2017 Vitamin D trials underway are unlikely to be useful – Jan 2015 Fractures not reduced by small amounts of vitamin D - meta-analysis Dec 2017 Vitamin D intervention -100 active clinical trials as of May 2018 Autism is associated with low vitamin D – meta-analysis Oct 2015 The Misuse of Meta-analysis in Nutrition Research (and vitamin D) – JAMA Oct 2017 Rheumatic diseases not helped by Vitamin D – if you ignore what and how much was given – meta-analysis June 2017 Systematic Reviews of Vitamin D underway as of May 2017 Should adults take vitamin D supplements to prevent disease (No, if you ignore most of the studies) - Nov 2016 Birth weight and length increased with high levels of vitamin D – meta-analysis March 2015 Gut problems more likely if low vitamin D (IBD: 1.6, UC: 2.3) – meta-analysis Aug 2015 Off topic: Why Is the Federal Government Afraid of Fat - NYT July 2015 Falls are prevented by vitamin D - provided you get enough - Dec 2014 Question – I have a health problem associated with low vitamin D – should I take Vitamin D

This page is in the following categories (# of items in each category)

Meta-analysis of Vitamin D 653 Evidence for D 57 Category 156

Backlinks
One pill every two weeks gives you all the vitamin D most adults need Consensus that treatment of Rickets by a single supplement took 80 years, how...VitaminDWiki Mega-Search (Interim Version)Major heart problems if have less than 15 ng of Vitamin D – Nov 2015 Overview Breast Cancer and Vitamin D Intervention - Vitamin D Vitamin D fights many health problems – an umbrella review of 508 studies – J...MegaSearchOverview Criteria to associate a health problem with low vitamin D More than half of the FDA entire budget now comes from Big Pharma, not the go...Do not expect a doctor to recommend a pill which will eliminate his job (vita...Why many vitamin D trials fail to find benefits - Nov 2016 Breast Cancer again associated with low vitamin D – 15th meta-analysis Sept 2020 RCTs probably not the future gold standard - CDC former head – July 2017 VitaminDWiki had a booth at Vitamin D Workshop May 2019 Review of meta-analyses of non-skeletal benefits of vitamin D (Mortality, RTI...Do not expect your doctor to know about vitamin D Evidence-Based Vitamin D Conference - Dec 2014 Overview of Vitamin D Meta-analysis and RCT for Caucasians - July 2017 Treatment by Vitamin D Vitamin D voting by panel – agreed upon bone health and high risk of chronic ...Vitamin D publications and supplementation are increasing, need more studies ...Hand, Foot, and Mouth disease (virus) strongly associated with low vitamin D ...Vitamin D trials underway are unlikely to be useful – Jan 2015 Fractures not reduced by small amounts of vitamin D - meta-analysis Dec 2017 Vitamin D intervention -100 active clinical trials as of May 2018 Autism is associated with low vitamin D – meta-analysis Oct 2015 The Misuse of Meta-analysis in Nutrition Research (and vitamin D) – JAMA Oct ...Rheumatic diseases not helped by Vitamin D – if you ignore what and how much ...Systematic Reviews of Vitamin D underway as of May 2017 Should adults take vitamin D supplements to prevent disease (No, if you ignor...Birth weight and length increased with high levels of vitamin D – meta-analys...Gut problems more likely if low vitamin D (IBD: 1.6, UC: 2.3) – meta-analysis...Off topic: Why Is the Federal Government Afraid of Fat - NYT July 2015 Falls are prevented by vitamin D - provided you get enough - Dec 2014 Question – I have a health problem associated with low vitamin D – should I t...

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Health Problems and D

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Meta-analysis of Vitamin D

Vitamin D has climbed the pyramid for decades, but has not yet reached the top

International prospective register of on-going systematic reviews: 569 reviews of Vitamin D as of March 2020

Table of contents

VitaminDWiki - Vitamin D meta-analyses for different health problems

20 Most-visited pages in Meta-analysis category in VitaminDWiki

All of the articles in Meta-Analysis - sorted by date

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Health Problems and D