Effects of Intravenous and Oral Magnesium on Reducing Migraine: A Meta-analysis of Randomized Controlled Trials.
Pain Physician. 2016 Jan;19(1):E97-112.
Chiu HY1, Yeh TH2, Huang YC3, Chen PY3.
1School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
2Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
3Department of Neurosurgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
- Cluster headaches virtually eliminated in 7,000 people with high-dose vitamin D and cofactors - Feb 2022
- Vitamin D increases mineral availability which protect against toxic elements - July 2015
- All items in category Magnesium
365 items - Headache category has the following
Metal Migraine No Migraine Ratio Cadmium 0.36 ug 0.09 ug 4X MORE if decrease Iron 0.97 ug 0.48 ug 2X MORE if decrease Lead 1.48 ug 0.78 ug 2X MORE if decrease Magnesium 10.6 ug 34.5 ug 3.5X LESS if increase Zinc 0.24 ug 5.77 ug 24X LESS if increase Pages listed in BOTH the categories Headache and Magnesium
- Magnesium Pidolate may be a good form to reduce headaches – Aug 2020
- Headaches decreased by Vitamin D, Magnesium etc. – Review March 2022
- Cluster Headaches treated by high-dose Vitamin D, etc. (interview and transcript) - Feb 2022
- Migraine headaches cut in half by 4,000 IU of vitamin D – RCT Sept 2018
- Magnesium in Healthcare (Rickets, Stones, Pregnancy, Depression, etc.) with level of evidence – Sept 2017
- Acute Migraine 35 times more likely if low Magnesium levels – May 2016
- Migraine headaches quickly reduced with Magnesium – Meta-analysis Jan 2016
- Cluster headaches virtually eliminated in 7,000 people with high-dose vitamin D and cofactors - Feb 2022
- Headache
- Migraines may be due to lack of lack of Magnesium in half of sufferers – May 2012
- Headache with vitamin D may mean you need Magnesium
Download the PDF from VitaminDWiki
BACKGROUND:
Migraine attack has been associated with magnesium deficiency. Previous studies investigating the effect of intravenous and oral magnesium on acute migraine attacks and the prevention of migraine have produced equivocal findings.
OBJECTIVE:
To evaluate the effects of intravenous magnesium on acute migraine attacks and oral magnesium supplements on migraine prophylaxis.
STUDY DESIGN:
A meta-analysis of randomized controlled trials (RCTs). Electronic databases, namely EMBASE, PubMed, the Wanfang Data Chinese Database, and the China Knowledge Resource Integrated Database were searched from inception to February 24, 2015.
METHODS:
This review was conducted according to the guidelines of the PRISMA. Only RCTs evaluating the effects of intravenous or oral magnesium on migraine compared with a control group were included.
RESULTS:
A total of 21 studies were included. Of which,- 11 studies investigated the effects of ntravenous magnesium on acute migraine (948 participants) and
- 10 examined the effects of oral magnesium on migraine prophylaxis (789 participants).
Intravenous magnesium significantly relieved acute migraine within 15 - 45 minutes, 120 minutes, and 24 hours after the initial infusion (Odd ratios [ORs] = 0.23, 0.20, and 0.25, respectively).
Oral magnesium significantly alleviated the frequency and intensity of migraine (ORs = 0.20 and 0.27).
LIMITATIONS:
Some of the included studies did not adopt adequate randomization methods.
CONCLUSIONS:
Intravenous magnesium reduces acute migraine attacks within 15 - 45 minutes, 120 minutes, and 24 hours after the initial infusion and oral magnesium alleviates the frequency and intensity of migraine. Intravenous and oral magnesium should be adapted as parts of multimodal approach to reduce migraine.PMID: 26752497
Short URL is.gd/MgMigraine
Migraine headaches quickly reduced with Magnesium – Meta-analysis Jan 2016Printer Friendly Follow this page for updates8338 visitors, last modified 10 Dec, 2016, This page is in the following categories (# of items in each category)