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Endometrial cancer and Vitamin D – many studies

4+ VitaminDWiki pages with ENDOMETRIAL in the title

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Items found: 4

12,800 studies of endometrial cancer and vitamin D - April 2023

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  • Prospective analysis of vitamin D and endometrial cancer risk - March 2013 FREE PDF no assocaition, but everyone had low vitamin D levels
  • A population-based cohort study on sun habits and endometrial cancer - June 2009
    • "Exposure to artificial sun by the use of sun beds >3 times per year was associated with a 40% reduction in the risk of endometrial cancer, probably by improving the vitamin D levels during winter."

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Study: Vitamin D levels not high enough to find an association with EC - 2012

Prospective analysis of vitamin D and endometrial cancer risk
J. J. Liu1,2,*, K. A. Bertrand1,2, S. Karageorgi3, E. Giovannucci1,2,4, S. E. Hankinson1,2, B. Rosner2,5, L. Maxwell6, G. Rodriguez7 and I. De Vivo1,2

Background This is the first prospective cohort analysis on the association between vitamin D and endometrial cancer incorporating time-varying predicted plasma 25-hydroxyvitamin D [25(OH)D].

Methods The prospective cohort analysis of predicted 25(OH)D and total dietary vitamin D intake used the Cox proportional hazards model, and involved 644 incident endometrial cancer events from 1986 to 2006 in the Nurses' Health Study. Genotyping and unconditional logistic regression were carried out on 572 endometrial cancer cases and their matched controls on 12 single nucleotide polymorphisms (SNPs) in vitamin D-related genes.

Results There was no significant association between predicted 25(OH)D and endometrial cancer incidence, with the hazard ratio for the highest (versus the lowest) quintile of predicted 25(OH)D as 1.00 (95% CI 0.73–1.36) (p-trend = 0.33).
There was also no significant association involving total dietary vitamin D.
No significant associations between any of the vitamin D-related SNPs and endometrial cancer were observed.

Conclusion Both predicted 25(OH)D and total dietary vitamin D intake were not associated with endometrial cancer incidence.
These results suggest that vitamin D may not protect against the development of endometrial cancer.
However, the low and narrow vitamin D exposure range in the cohort may limit generalizability of the results.

Agreed: Most cancers are NOT hindered when vitamin D levels <30 nanograms

derived from Grassroots 2013

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Attached files

ID Name Comment Uploaded Size Downloads
1702 endometrial.pdf PDF admin 09 Nov, 2012 17:09 107.63 Kb 952