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Low Magnesium associated with severe COVID – many studies

Can Maintaining Optimal Magnesium Balance Reduce the Disease Severity of COVID-19 Patients? –March 2022

Front. Endocrinol. 13:843152. doi: 10.3389/fendo.2022.843152
Mark Eskander and Mohammed S. Razzaque
Department of Pathology, Lake Erie College of Osteopathic Medicine, Erie, PA, United States

The coronavirus disease (COVID-19) caught the world by surprise, claiming millions of lives due to its deadly effects. Ongoing research studies evaluate the measures that can reduce the severity of symptoms in patients infected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Magnesium is an essential nutrient that has many studied benefits in humans. This brief commentary aims to describe the potential benefits of magnesium on COVID-19 patients and the reported effects of low versus high magnesium levels in SARS-CoV-2 infected individuals. Also, the potential benefits of vitamin D and how magnesium acts as a cofactor to activate vitamin D functions are elaborated. The results of the existing studies point towards evidence that magnesium may have significant benefits in reducing the severity of COVID-19 symptoms. There is also evidence that magnesium-dependent vitamin D activities may have antiviral effects, thus potentially being able to reduce rates of COVID-19 infection, which is a hypothesis that should be further tested.

The COVID-19 primarily causes respiratory distress but has a broad range of other clinical manifestations and affects various organs and systems in the body. COVID-19 is especially lethal to elderly populations at higher risk (1,2). As of September 3rd, 2021, the current worldwide death rate of individuals infected by COVID-19 is 4,539,723 (World Health Organization). Many public health measures have already been taken to try to prevent the spread of COVID-19, such as face mask mandates, vaccine inoculation, quarantine, social distancing, limited capacities at public venues, and a shift to online work. However, COVID-19 is still proving to be a health concern as cases of infection continue to rise. The continued infection of individuals by COVID-19 may be due to the high transmissibility of the virus (3-6). It is also proposed that some of the new variants of the virus are even more rapidly transmissible and lethal. Thus, certain preventative measures are essential to find to reduce the severity of symptoms and improve patient outcomes in individuals that have been infected, since the prevention of infection is not always possible.

Basic nutrients that optimize physiologic functions in the body, such as magnesium, maybe used as a prophylactic measure that can improve patient outcomes in individuals infected by SARS-CoV-2, and potentially even reduce the intensity of the infection by the virus by potentiating vitamin D functions. In the U.S., more than 50% of people are magnesium deficient (7, 8), and magnesium deficiency is also prevalent in many other countries. The low level of magnesium in the general population may make individuals more vulnerable to viral insults. The high prevalence of magnesium deficiency makes it important to determine how optimal and suboptimal magnesium levels affect COVID-19 patient outcomes, which this paper aims to elaborate on.
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10 Magnesium and COVID articles

VitaminDWiki - 25 studies in both categories Virus and Magnesium

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VitaminDWiki - Magnesium and Vitamin D contains

328 items in category, see also

Mg and Vitamin D

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Number of studies in both of the categories of Magnesium and:

Bone 15,  Cardiovascular 17,   Diabetes 26. Depression 14,  Obesity 11,   Omega-3 30,  Zinc 21,  Pregnancy 10,  Headache 10,   Virus 25,   Calcium 24   Virus 25   Mortality 7   Hypertension 11   Inflammation 3   Pain 7 etc.

Role of Magnesium in Acute and Long COVID - Drbeen video Jan 2023

YouTube 41 minutes

Magnesium is an essential mineral/nutrient required for more than 600 enzymatic actions in our body. Magnesium levels are also tied closely with the activation of vitamin D. Magnesium is involved in smooth muscle relaxation, neuroprotection, innate arm modulation, gut microbiome modulation, and much more. Let's look at the role of magnesium and importance of its levels to be correct in our body. If you like this content and want more, I am doing a special lifetime membership offer.
Click here: https://www.drbeen.com/yt-special-p/ Want to support this work?: Buy me a coffee smile https://www.buymeacoffee.com/DrMobeen... Become my patron: https://www.patreon.com/mobeensyed?fa... PayPal: https://paypal.me/mobeensyed?locale.x... My substack: https://mobeensyedmd.substack.com/ #drbeen #koolbeens #COVID
sDisclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Monday, Jan. 23 2023

Frontiers | Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study https://www.frontiersin.org/articles/...

The relevance of magnesium homeostasis in COVID-19 - PMC https://www.ncbi.nlm.nih.gov/pmc/arti...

Frontiers | Can Maintaining Optimal Magnesium Balance Reduce the Disease Severity of COVID-19 Patients? https://www.frontiersin.org/articles/...

Impact of Magnesium Supplementation in Muscle Damage of Professional Cyclists Competing in a Stage Race - PMC https://www.ncbi.nlm.nih.gov/pmc/arti... 

The Role of Magnesium in Neurological Disorders - PMC https://www.ncbi.nlm.nih.gov/pmc/arti...

Neural Mechanisms of Autonomic Dysfunction in Neurological Diseases https://www.hindawi.com/journals/np/2...

Magnesium relaxes arterial smooth muscle by decreasing intracellular Ca2+ without changing intracellular Mg2+. - PMC https://www.ncbi.nlm.nih.gov/pmc/arti...

Frontiers | The Role of Proprotein Convertases in the Regulation of the Function of Immune Cells in the Oncoimmune Response https://www.frontiersin.org/articles/...

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Attached files

ID Name Comment Uploaded Size Downloads
18835 Mg COVID letter to editor.pdf admin 19 Nov, 2022 11:26 265.77 Kb 24
18741 Mg and COVID.jpg admin 29 Oct, 2022 00:44 63.54 Kb 216
18740 COVID is more severe if low Magnesium_CompressPdf.pdf PDF 2022 admin 29 Oct, 2022 00:43 145.62 Kb 49