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Latent Tuberculosis 44 percent less likely if Vitamin D more than 30 ng - 14th meta-analysis Jan 2022

Vitamin D and the risk of latent tuberculosis infection: a systematic review and meta-analysis

BMC Pulmonary Medicine(2022) 22:39 https://doi.org/10.1186/s12890-022-01830-5
Yan Cao11, Xinjing Wang11, Ping Liu3t, Yue Su , Haotian Yu* and Jingli Du1*

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Objective: Latent tuberculosis infection (LTBI) may be a risk of developing tuberculosis (TB) and thus a health hazard. The aim of this meta-analysis is to explore the association between vitamin D and LTBI.

Methods: Databases including PubMed, Embase, Scopus, and ProQuest were electronically searched to identify observational or interventional studies that reported the association between vitamin D and LTBI. The retrieval time is limited from inception to 30 September 2021. Two reviewers independently screened literature, extracted data, and assessed risk bias of included studies. Meta-analysis was performed by using STATA 12.0 software.

Results: A total of 5 studies involving 2 case-control studies and 3 cohort studies were included. The meta-analysis result showed that the risk of LTBI among individuals was not associated with high vitamin D level (OR 0.51,95% CI 0.05-5.65, P=0.58). The result from cohort studies also suggested that relatively high vitamin D level was not a protective factor for LTBI (RR = 0.56, 95%CI 0.19-1.67, P = 0.300).

Conclusions: Our meta-analysis suggested that serum vitamin D levels were not associated with incidence of LTBI, and relatively high serum vitamin D level was not a protective factor for LTBI. Further RCTs are needed to verify whether sufficient vitamin D levels and vitamin D supplementation reduces the risk of LTBI.
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VitamindWiki - Overview Tuberculosis and Vitamin D has

There are many indications that vitamin D both PREVENTS and TREATS TB

TB and vitamin D 117 items

VitamindWiki -Tuberculosis meta-analyses


Vitamin D Receptor gene reduces how much vitamin D gets to cells (TB in this case)


Created by admin. Last Modification: Tuesday February 1, 2022 18:31:50 GMT-0000 by admin. (Version 3)

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16977 TB Fig 3.jpg admin 01 Feb, 2022 02:43 40.83 Kb 55
16976 TB Meta Jan 2022.pdf PDF 2022 admin 01 Feb, 2022 02:40 985.65 Kb 70
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