Vitamin D status and risk of non-Hodgkin lymphoma: An updated meta-analysis
Hye Yin Park , Yun-Chul Hong, Kyoungho Lee, Jaewoo Koh, https://doi.org/10.1371/journal.pone.0216284
- Hodgkin’s lymphoma and Vitamin D Receptor - June 2012
- Vitamin D Insufficiency and Prognosis in Non-Hodgkins Lymphoma
- Lymphoma, leukemia etc, survival poor if low vitamin D – meta-analysis March 2015
- Lymphoid cancer deaths cut in half with 400 IU of vitamin D and 1 gram of Calcium (WHI) – RCT Nov 2017
Sun/UVB is perhaps better than Vitamin D for preventing some Cancers
Items in both categories Cancer and UV:
- 23 Cancers in the US are associated with low UVB - Grant April 2024
- Some cancer rates are reduced when live at high altitude, but other cancers increase after a few generations – March 2021
- Book: Sunlight, UV, Vitamin D and Receptor, Skin and other Cancers - Dec 2020
- More Cancer if less sun – model adding climate helps (need additional factors) – Nov 2019
- Non-Hodgkin Lymphoma 20 percent more likely if low UV – meta-analysis April 2019
- Embrace the Sun – benefits of the sun (Nitric Oxide etc.) – book June 2018
- Less intestinal cancer in mice if add vitamin D, but even less with ultraviolet light – June 2014
- Cancer incidence in 87 countries is related to food, smoking, alcohol, GDP, and UVB - Jan 2014
- 4 uses of tanning beds per year did not reduce rate of internal cancers – Oct 2013
- Some childhood cancer 30% less likely in parts of California with more UVB – April 2013
- The sun appears better at reducing incidence of some cancers than vitamin D – Dec 2012
- Solar UVB reduces Cancer Risk – Grant, Jan 2013
- A review of the evidence regarding the solar ultraviolet-B-vitamin D-cancer hypothesis - Oct 2012
- More UVB is associated with less cancer – study of 450,000 people – April 2012
- Getting little UV is associated with 15 types of Cancer – Jan 2012
- Lack of solar UVB in US is associated with some Cancers - 2006
- Use of tanning beds would reduce associated deaths by 10X – Oct 2011
- Some cancer due to low UV – Grant – April 2010
- China has documented that less UV results in more cancer – June 2010
- Grassroots PDF and video updates May and June 2010
Other diseases appear to be prevented/treated by UV, perhaps better than Vitamin D: MS is an example
The articles in both of the categories MS and UV are:
- Multiple Sclerosis treated equally by UVB and weekly 50,000 IU of Vitamin D – RCT July 2023
- Mutiple Sclerosis half as likely in children spending 30 to 60 minutes per day in the sun – Dec 2021
- Sun reduces risk of Multiple Sclerosis via both Vitamin D and another way – Dec 2019
- UV helped EAE mice (MS) designed to not respond to Vitamin D – Oct 2019
- Multiple Sclerosis 2X more likely if low winter UV – June 2018
- Multiple Sclerosis half as likely if get plenty of sunshine (not a news item) – March 2018
- Clinically Isolated Syndrome progresses to Multiple Sclerosis, unless UVB treatments – RCT Dec 2017
- Vitamin D and Sun conference – Germany June 2017
- Multiple Sclerosis suppressed by an Ultraviolet wavelength not associated with Vitamin D (mice) – Nov 2016
- Multiple Sclerosis helped by UV – possibly via cytokines, etc. – Oct 2015
- Hypothesis – Multiple Sclerosis risk increases with low UV, viral infections, and antibiotics in childhood – March 2015
- How UVB reduces autoimmune diseases such as Multiple Sclerosis – April 2014
- UV decreases Multiple Sclerosis via cis-urocanic acid (and via vitamin D) – June 2013
- MS prevention by UV is 2X better than prevention by vitamin D levels – Jan 2012
- There is more in UV than vitamin D which suppresses MS in mice – April 2010
- UV produces more than vitamin D – Aug 2011
- Lack of UV 20X more associated with MS than any other variable – Dec 2010
- Hypothesis - more in sunshine than vitamin D to reduce MS – Feb 2010
- MS UV and Vitamin D – 2009
- Lack of UV increased offspring MS - April 2010
- Mouse MS: UVB but not Vitamin D reduced incidence - April 2010
Download the PDF from VitaminDWiki
This meta-analysis aimed to extensively investigate the association between various measures of vitamin D status and non-Hodgkin lymphoma (NHL) and its subtypes.
Methods: We searched MEDLINE (PubMed), Embase, and the Cochrane Library in February 2018. Two authors independently reviewed and selected articles based on predetermined criteria.
Results
A total of 30 studies with 56,458 NHL cases were finally selected, with 24, 9, and 3 studies on sunlight/ultraviolet radiation (UVR) exposure, dietary intake, and serum/plasma 25-hydroxyvitamin D levels, respectively. Significant protective effects of overall sunlight/UVR exposure on NHL and subtypes were observed, with summary relative risks (RRs) ranging from 0.67–0.80 (RR for NHL = 0.80; 95% confidence interval [CI]: 0.71–0.90) among subjects with high exposure compared to those with low exposure. The results were consistent with various classifications of sunlight/UVR exposure. In contrast, when exposure measures of dietary vitamin D intake (RR for NHL = 1.03; 95% CI: 0.90–1.19) and serum/plasma 25-hydroxyvitamin D levels (RR for NHL = 0.97; 95% CI: 0.82–1.15) were used, risk estimates were inconsistent or non-significant for NHL and the subtypes.
Conclusion
While risk estimates varied by different measures of vitamin D status, a protective effect of sunlight/UVR exposure on NHL incidence was verified, across most of the tested subtypes as well as exposure categories.
Non-Hodgkin's lymphoma occurs when your lymphocytes don't die
Normally, lymphocytes go through a predictable life cycle. Old lymphocytes die, and your body creates new ones to replace them.
In non-Hodgkin's lymphoma, your lymphocytes don't die, and your body keeps creating new ones. This oversupply of lymphocytes crowds into your lymph nodes, causing them to swell. Mayo Clinic