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Overview Breast Cancer and Vitamin D


Vitamin D associated with less Breast Cancer

30 percent reduced chance of breast cancer death if take tiny amount of vitamin D (one-a-day) – Oct 2013
Breast Cancer chance decreased 16 percent for every extra ng of vitamin D – Jan 2013
Breast Cancer survival 2X more likely if vitamin D sufficient – meta-analysis May 2013
If have breast cancer, should increase vitamin D to more than 30 ng – Jan 2012
3.2 percent less Breast Cancer for 2.4 ng more vitamin D – meta-analysis June 2013
Breast Cancer post menopause down 12 percent for every 5 ng of vitamin D – meta-analysis May 2013
Postmenopausal Breast cancer 63 percent more likely if low vitamin D – July 2012
Breast tumor 1 inch bigger for each 1 ng decrease in vitamin D – Dec 2011
Walking an hour a day (more vitamin D) decreased chance of breast cancer by 14 percent – Oct 2013

Breast Cancer and Vitamin D - Overview

Vitamin D and breast cancer – overview – Oncologist 2012
Breast Cancer and long term vitamin D studies – March 2013
Vitamin D and Breast Cancer Incidence and Outcome - Jan 2013
Compelling evidence – Breast Cancer and vitamin D – Dissertation June 2012
How Vitamin D reduces chance of breast cancer – review May 2012
2X increase in metastatic breast cancer in young women since 1976 – Feb 2013 2X increase - like 30 other diseases
Not enough women willing to stop taking vitamin D to permit breast cancer clinical trial – June 2012
Wide variety of data on vitamin D and breast cancer, but still insufficient clinical data – Feb 2013
If have BRCA1 breast cancer gene, instead of double mastectomy, get 40ng of vitamin D – Jan 2013
Breast cancer 2X more likely if have taken statins for 10 years – July 2013
  Statins decrease vitamin D. Low vitamin D increases chance of Breast Cancer

There have been MANY reviews of Breast Cancer Studies

Video and books on Breast Cancer
Breast Cancer and Vitamin D: Dr Garland - video June 2013
Vitamin D Might Be Able to Slash Your Breast Cancer Risk by 90 Percent - Baggerly, Mercola: May 2013
   Baggerly setup http://www.grassrootshealth.net/

Treatment with Vitamin D after Diagnosis

Vitamin D after breast cancer diagnosis
Women with breast cancer safely take 10,000 IU daily – Jan 2010
85 percent less risk of death from Breast Cancer when vitamin D levels higher than 30 ng – May 2012
Triple-negative breast cancer is 3X more frequent if less than 32 ng of vitamin D – March 2012
Vitamin D and Cancer Mortality – review Jan 2013
2X more likely to survive breast cancer disease free if lots of vitamin D – July 2011

Treatment with Vitamin D during Breast Cancer Therapy

can reduce the effects of chemo, and radiation
Probably need loading dose to restore levels in days, rather than waiting 6 months
Cancer Chemotherapy and vitamin D – Review March 2013
Chemotherapy might be amplified by vitamin D
Vitamin D levels dropped 3 ng during cancer chemotherapy – May 2012
Breast Cancer Chemotherapy initially decreases vitamin D levels – May 2012
If vitamin D levels were not changed, toxicity to chemotherapy did not vary with levels – May 2012
Vitamin D Shows Potential in Natural Chemotherapy April 2010
Vitamin D and breast cancer radiation
Vitamin D3 sensitizes breast cancer to radiation treatment - increasing cancer cell death – May 2010

Vitamin D helps after breast cancer therapy

Reduce pain, hair loss, fatigue
Overview Pain and Vitamin D
Breast Cancer medicine pain reduced with 4300 IU vitamin D – RCT June 2012
Higher quality of life associated with higher levels of vitamin D
If you cannot readily get medical treatment, consider Alternative Med such as vitamin D
7 improvements in lives of veterans with chronic pain with 50,000 IU vitamin D weekly – June 2012
Vitamin D reduces hair loss
2000 IU of vitamin D reduced fatigue of advanced cancer – RCT May 2012
Women taking Vitamin D had fewest deaths after post-menopause breast cancer – May 2013

Prevent recurrence of Breast Cancer

Breast Cancer recurred more when less than 20 ng of vitamin D – Oct 2010
Recurrence of breast cancer not associated with vitamin D levels – Jan 2011
Breast cancer survivors should take vitamin D – Mar 2010

52 Breast Cancer clinical trails with Vitamin D intervention (June 2018)

Example: 40,000 IU of vitamin D DAILY to possibly eliminate need for surgery

Dark Skinned women have worse problems with breast cancer

Breast cancer worse for black women – Sept 2011
Vitamin D receptor in breasts and breast cancer vary with race – March 2013
Genes may account for some of AA Breast Cancer – April 2012
Breast cancer more deadly for blacks than whites
Hypothesis: Blacks get more cancer than whites due to lower levels of vitamin D – June 2012
Overview Dark Skin and Vitamin D
Differences in black and non-black mortality and vitamin D – Oct 2012

More about Vitamin D

Many people around the world are vitamin D deficient

Many reasons why vitamin D deficiency has become epidemic

Many ways to increase your vitamin D levels

Overview Vitamin D Dose-Response
Many hints that vitamin D megadoses cure some diseases
Dose response equations for Vitamin D
Overview Loading of vitamin D
Overview Toxicity of vitamin D hard to overdose
How you might double your response to vitamin D

When taking more Vitamin D you must also balance micronutrients - such as Magnesium and Calcium

Hypothesis: increased breast cancer if not enough magnesium – Sept 2010
Hypothesis – anticancer benefits from synergy of omega-3 and vitamin D – May 2011
Hypothesis: Premenopausal Iron deficiency causes increased recurrence of breast cancer – 2008

Vitamin D comes in many forms: vegan, liquid, poor digestion . .

Vitamin D3 for Vegans
Quantum dots should deliver active vitamin D directly to inflammatory breast cancer tumors – Feb 2013
Active form of vitamin D appears to help prevent and treat some cancers – Feb 2011
Forms of vitamin D: not have to take pills, poor digestion, etc.

You can also get vitamin D from the sun and UV bulbs

The sun appears better at reducing incidence of some cancers than vitamin D – Dec 2012
Less UV: 2X more breast cancer – June 2011
More Cancer, less Solar Radiation - 1941
Need lots of UV AND vitamin D to reduce risk of breast cancer – Jan 2011
Vitamin D, Sunlight and Cancer Connection – Holick Jan 2013
Solar UVB reduces Cancer Risk – Grant, Jan 2013
More UVB is associated with less cancer – study of 450,000 people – April 2012
Photodynamic therapy for Cancer might be helped by vitamin D – July 2012
A review of the evidence regarding the solar ultraviolet-B-vitamin D-cancer hypothesis - Oct 2012
How you can get more UV without getting too hot in the sun
How you can get more UV without exposing too much skin to the sun

Reasons for taking even more vitamin D

Obesity, trauma, major health problem
Not get much D from the sun: Dark Skin, Shut-in, Far from equator

If Breast Cancer runs in your family

Vitamin D level can be high, but little benefit: due to kidney, genes, low Magnesium etc.
County with 20 pcnt higher breast cancer rate has 2X more modified vitamin D receptor – July 2012
Breast Cancer incidence change by 40 percent with vitamin D receptor genes – Oct 2012
Genes breast cancer and vitamin D receptor - Sept 2010
CYP24A1 gene in cancer cells may actually deactivate vitamin D – Oct 2012
Genes such as CYP27B1, CYP24A1 and Vitamin D – JAMA Nov 2012

How vitamin D prevents and treats other cancers

Overview Cancer and vitamin D
Metastatic Cancer is maybe reduced by vitamin D - 5 articles
How Vitamin D prevents many cancers (c-MYC) – Nov 2012
Vitamin D and cancer: a view based of all models – April 2012
Advanced stage cancer 3X more likely if low level of vitamin D – March 2012
Possible ways that vitamin D does its magic

Breast cancer experience of Carole Baggerly - who survived and created GrassrootsHealth

From Oct 2015 newsletter
In 2005, when I had breast cancer, I learned many things. I truly came to understand that one of the biggest things one faces with a serious disease is a challenge to one's values. At the beginning, when diagnosed with a stage 3 tumor, 2.5 inches in diameter (yes, 2.5 inches), the oncologist said, "of course, you'll do surgery, chemo and radiation."

Value test #1: I have always believed that my body was able to essentially heal itself with some support by me and professionals. This was definitely a test of that. I looked at options but did not know enough to make any decisions other than the "norm." I felt very depressed about these options and suffered the treatments greatly.

Value test #2: During the 2nd round of chemo treatment, I had Paclitaxel which can create a very painful neuropathy, in my case, in the legs and feet. This was extremely debilitating and painful to me. I finally felt "NO! I will not allow this VIOLENCE against my body to continue." The value was non-violence, a very strongly held one. Little did I realize it applied to treatment of my own body.

This feeling of non-violence was so strong that I told my oncologist that I would not complete the last two sessions of this treatment. He tried to persuade me. I said no. He left the room. I still had questions and told the nurse I'd like to see him for my questions. She went out, came back with "He's writing up the charts and said for you to ask me and I'll go get your answers." He wouldn't come back to see me. I changed oncologists.

Value test #3: During radiation, there is definitely scattering of the beams and even though they are more targeted than in the past, there is significant impact on the thyroid (mine is gone), the heart and lung. During one session, I was bleeding from my chest (due to the burning) and again, told the radiologist I would do no more treatments. He was more reasonable, but still wanted me to continue. I did not.

Now, 10 years later, I have experienced demonstrable heart vessel damage, lung function problems. The value here is a re-establishment of the belief in my own body with a very focused effort on constantly learning and implementing nutritional and behavioral actions to keep me healthy.

These values are what led to the establishment of GrassrootsHealth - and, are what leads us to ask you to help us change the game, to change the questions from drug related solutions to the things we can do with appropriate nutrition (a big player, of course, is vitamin D) and actions.

Candidate graphics



derived from Grassroots 2013 Reductions in Vitamin D is.gd/VitDReductions see wikipage http://www.vitamindwiki.com/tiki-index.php?page_id=3057 see page http://is.gd/lowddeath Breast cancer incidence 3X increase.gif see wikipage http://www.vitamindwiki.com/tiki-index.php?page_id=2209 see wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=2563 see wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=396 see wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=1659 For more information, see wiki page http://www.vitamindwiki.com/tiki-index.php?page_id=1586 IU of vitamin D to add vs X Graph of dose vs week see wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=2681 PDF is at tiki-download_file.php?fileId=1480


Still needed

  1. Delete redundant/obsolete information
  2. Link to overviews, categories
  3. Write summary for each section
  4. Add Graphics
  5. Links to information on the web (Grassroots, etc.)
  6. Reduce/combine the number of entries, so as to reduce the amount of reading material.

See also web

See also web - other than Vitamin D

70 % of women with breast cancer have genes which indicate that Chemo is NOT needed - June 2018

  • Good News for Women With Breast Cancer: Many Don’t Need Chemo New York Times
    "The study, called TAILORx, is being published by The New England Journal of Medicine and was to be presented on Sunday (June 3) at a meeting of the American Society of Clinical Oncology in Chicago. The study began in 2006 and was paid for by the United States and Canadian governments and philanthropic groups. Genomic Health, the company that makes the gene test, helped pay after 2016."
    "For every 100 women we were treating, we were probably preventing about 4 distant recurrences.”
    "Of the 9,719 patients with complete follow-up information, 70 percent had scores of 11 to 25 on the gene test. They had surgery and radiation, and then were assigned at random to receive either endocrine therapy alone, or endocrine therapy plus chemo. The median follow-up was more than seven years. Over time, the two groups fared equally well. Chemo had no advantage. After nine years, 93.9 percent were still alive in the endocrine-only group, versus 93.8 percent in those who also got chemo. In the endocrine group, 83.3 percent were free of invasive disease, compared with 84.3 percent who got both treatments. There were no significant differences."

Mammography reduces BC death rate by 1 in 1000, but 10 in 1000 get treatment for no reason - Oct 2016

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Suggestions to help with Breast Cancer Treatment - Sept 2018

Advising Women Undergoing Treatment for Breast Cancer: A Narrative Review.
J Altern Complement Med. 2018 Sep/Oct;24(9-10):902-909. doi: 10.1089/acm.2018.0150.
Lemanne D1,2,3, Maizes V1.

A majority of women undergoing conventional treatment for breast cancer also undertake complementary and integrative approaches. Practitioners knowledgeable about the evidence base behind common integrative approaches can help patients attain improved quality of life, and at times, improved survival. Evidence-based recommendations include the following:

  • a plant-based diet for general health after diagnosis, and
  • carbohydrate restriction for patients with estrogen receptor-positive postmenopausal breast cancer may be prudent.
  • Other dietary recommendations include a 13-h daily overnight fast. Carefully selected patients may choose to fast the day before and the day of chemotherapy to decrease side effects.

Specific food recommendations include

  • avoidance or limitation of alcohol, and liberal culinary use of cruciferous vegetables, coffee, green tea, soy, and flaxseed.

Promising supplements include diindolylmethane and melatonin.
Omega 3 fatty acids may help with bone density in patients on aromatase inhibitors, but may increase chemotherapy resistance.
Findings regarding the usefulness of multivitamins, vitamin D, vitamin C, and vitamin E are weak and/or mixed

different exercise modalities may have different effects and thus play different roles in breast cancer therapy. Aerobic and resistance training combined during breast cancer chemotherapy may confer a survival benefit, while yoga may improve outcome in lymphedema patients.
Current evidence suggests that meditation, yoga, breathing, music therapy, guided imagery, and hypnosis may improve mood and quality of life during breast cancer treatment.
Acupuncture is useful for treating side effects of breast cancer therapies, including hot flushes, aromatase inhibitor-induced joint pain, chemotherapy-induced peripheral neuropathy, and vulvodynia.
Vaginal moisturizers and vaginal rings supplying low-dose estrogen can be useful in the treatment of symptoms of estrogen-deprivation states caused by breast cancer treatments; such symptoms include vaginal dryness, dyspareunia, and sexual dysfunction. Carbon dioxide laser technology can rejuvenate atrophied vaginal mucosa and relieve dyspareunia, allowing avoidance of estrogen therapy. Tertiary sexual health centers are available for referral.

Short url = http://is.gd/vitdbc

Overview Breast Cancer and Vitamin D        

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