Loading...
 
Toggle Health Problems and D

Low Vitamin D associated with preeclampsia - meta-analysis Feb 2022


Vitamin D Levels in Early and Middle Pregnancy and Preeclampsia, a Systematic Review and Meta-Analysis

Nutrients 2022, 14(5), 999; https://doi.org/10.3390/nu14050999

Vitamin D (VitD) shows a beneficial role in placentation, the immune system, and angiogenesis, and thus, VitD status may link to the risk of preeclampsia. A meta-analysis was conducted to investigate the association between VitD status in early and middle pregnancy and the risk of preeclampsia. A total of 22 studies with 25,530 participants were included for analysis.

  • Women with VitD insufficiency or deficiency had a higher preeclampsia rate compared to women with replete VitD levels (OR 1.58, 95% CI 1.39–1.79).
  • Women with VitD deficiency had a higher preeclampsia rate compared to women with replete or insufficient VitD levels (OR 1.35, 95% CI 1.10–1.66).
  • Women with insufficient VitD levels had a higher preeclampsia rate compared to women with replete VitD levels (OR 1.44, 95% CI 1.24–1.66).
  • Women with deficient VitD levels had a higher preeclampsia rate compared to women with replete VitD levels (OR 1.50, 95% CI 1.05–2.14).

Sensitivity analysis showed the results were stable after excluding any one of the included studies. In conclusion, our systematic review suggested that VitD insufficiency or deficiency was associated with an increased risk of preeclampsia.
No such attachment on this page


VitaminDWiki Meta-analysis pages with PREECLAMPSIA in title

This list is automatically updated

Items found: 9

Articles in both Pregnancy AND Meta-analysis


Articles in both Pregnancy and Hypertension (preeclampsia)


Created by admin. Last Modification: Thursday March 24, 2022 21:45:51 GMT-0000 by admin. (Version 3)

Attached files

ID Name Comment Uploaded Size Downloads
17109 Preeclampsia meta.pdf PDF 2022 admin 27 Feb, 2022 10:40 1.90 Mb 26
See any problem with this page? Report it (WORKS NOV 2021)