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Genetics

247 articles in the Genetics category

see also

Vitamin D blood test misses a lot
Blood Test Misses a lot (VDW 3439)

  • Snapshot of the literature by VitaminDWiki as of early 2019
  • Vitamin D from coming from tissues (vs blood) was speculated to be 50% in 2014, andi by 2017 was speculated to be 90%
  • Note: Good results from a blood test (> 40 ng) does not mean that a good amount of Vitamin D actually gets to cells
  • A Vitamin D test in cells rather than blood was feasible (2017 personal communication)
  •    Commercially available 2019
    However test results would vary in each tissue due to multiple genes
  • Good clues that Vitamin D is being restricted from getting to the cells
    1) A vitamin D-related health problem runs in the family
       especially if it is one of 51+ diseases related to Vitamin D Receptor
    2) Slightly increasing Vitamin D show benefits (even if conventional Vitamin D test shows an increase)
    3) Vitamin D Receptor test (<$30) scores are difficult to understand in 2016
        easier to understand the VDR 23andMe test results analyzed by FoundMyFitness in 2018
    4) Back Pain
        probably want at least 2 clues before taking adding vitamin D, Omega-3, Magnesium, Resveratrol, etc
          The founder of VitaminDWiki took action with clues #3&4


Additional information on the Genes in VitaminDWiki

Gene# of pages Location
CYP27A1449 (Sept 2019) Liver
CYP2R1 826 (Sept 2019)Liver & Tissue
CYP27B11430   (Sept 2019) Kidney & Tissue
CYP24A1 1280   (Sept 2019) excrete excess




CYP450 family includes CYP24 and CYP3A
The first chart on this page until Oct 2017 had been
Image

The following chart triggered the creation of the chart at the top of this page

+Image

Note the assumption, which may be correct, that the immune system only responds to tissue Vitamin D, rather than from blood vitamin D

Immune modulation by Vitamin D, food allergy, chart of genes – July 2015 has the following chart
Genes and vitamin D  page 6748

Pancreatic Cancer massively deregulates the local Vitamin D receptors and CPY24A1 – July 2014 is an example of massive gene changes
Image
     shaded text and numbers in the chart were added by VitaminDWiki
Most-visited 10 pages in Genetics category

Id Page Hits Last modification Creator Categories
3439 Genetics 36264
04 Nov, 2019 17:25
ricks99 Genetics
Vitamin D Receptor
Vit D Binding Protein
Category
2269 Pharmacology of vitamin D - April 2011 16084
06 May, 2013 21:02
admin Health
Genetics
Overview for doctors
4017 Vitamin D - Health panacea or false prophet (Klotho gene) – Jan 2013 15775
14 Apr, 2013 01:32
admin Genetics
3335 Vitamin D levels are strongly associated with genes: overview of twin studies – Nov 2012 14645
04 Jan, 2015 02:37
admin Genetics
Vitamin D Receptor
1099 Blacks may not need as much Vitamin D (for their bones) 13803
07 Jul, 2018 10:56
admin Skin - Dark
Bone - Health
Genetics
645 The more the African Ancestry, the lower the vitamin D level – July 2010 12541
10 Jan, 2019 11:15
admin Skin - Dark
Genetics
2248 Possible ways that vitamin D does its magic 12379
03 Jun, 2014 20:45
admin More D topics
Cancer
Genetics
7403 Health problems that run in families are often associated with low vitamin D 11970
13 Feb, 2018 23:52
admin Health
Genetics
Top news
Vitamin D Receptor
Vit D Binding Protein
1447 CYP24A1 enzyme and Vitamin D 11720
22 Jul, 2019 19:57
admin Genetics
1132 Schizophrenia and vitamin D have latitude-related genes – Nov 2010 10944
22 Feb, 2019 16:42
admin Vitamin D Far from equator
Genetics
Cognitive


All articles in both Pregnancy and Genetics:


All articles in both Multiple Sclerosis and Genetics:

Here are all 247 articles


Genes on the web

  • The Genes That Never Go Out of Style Sept 2018
    about 16% of all genes were known by 1991, That same 16% are the focus of half of all Genetics papers in 2015
    25% of all genes have never been the focus of a single scientific paper
    "Even supposedly game-changing techniques like crispr have altered the landscape of gene popularity very little"

Genetics        

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