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338 articles in the Genetics category

see also

Vitamin D blood test misses a lot
in Visio for 2023

  • Vitamin D from coming from tissues (vs blood) was speculated to be 50% in 2014, and by 2017 was speculated to be 90%
  • Note: Good blood test results (> 40 ng) does not mean that a good amount of Vitamin D actually gets to cells
  • A Vitamin D test in cells rather than blood was feasible (2017 personal communication)   Commercially available 2019
    • However, test results would vary in each tissue due to multiple genes
  • Good clues that Vitamin D is being restricted from getting to the cells
    1) A vitamin D-related health problem runs in the family
        especially if it is one of 51+ diseases related to Vitamin D Receptor
    2) Slightly increasing Vitamin D shows benefits (even if conventional Vitamin D test shows an increase)
    3) DNA and VDR tests - 120 to 200 dollars $100 to $250
    4) PTH bottoms out ( shows that parathyroid cells are getting Vitamin d)
       Genes are good, have enough Magnesium, etc.
    5) Back Pain
       probably want at least 2 clues before taking adding vitamin D, Omega-3, Magnesium, Resveratrol, etc
      • The founder of VitaminDWiki took action with clues #3&5

Many reasons for the decrease in Vitamin D getting to blood and cells

Click on chart for details

Gene# of pages Location
CYP27A1449 (Sept 2019) Liver
*CYP2R1826 (Sept 2019)Liver & Tissue
CYP27B11430   (Sept 2019) Kidney & Tissue
CYP24A128 in title - May 2022] excrete excess

Sample of studies

CYP450 family includes CYP24 and CYP3A
The first chart on this page until Oct 2017 had been

The following chart triggered the creation of the chart at the top of this page


Note the assumption, which may be correct, that the immune system only responds to tissue Vitamin D, rather than from blood vitamin D

Immune modulation by Vitamin D, food allergy, chart of genes – July 2015 has the following chart
Genes and vitamin D  page 6748

Pancreatic Cancer massively deregulates the local Vitamin D receptors and CPY24A1 – July 2014 is an example of massive gene changes
     shaded text and numbers in the chart were added by VitaminDWiki
Most-visited 10 pages in Genetics category

Id Page Hits Last modification Creator Categories
14350 Gestational Diabetes and Vitamin D - many studies 105466
10 Apr, 2024 10:33
admin Pregnancy
Vitamin D Receptor
14254 CYP2R1 gene reduces response to Vitamin D - many studies 93611
19 Jan, 2024 15:02
admin Genetics
3439 Genetics 91901
23 May, 2024 09:25
ricks99 Genetics
Vitamin D Receptor
Vit D Binding Protein
14180 PTH and Vitamin D - many studies 90569
29 Feb, 2024 20:21
admin Genetics
Thyroid and parathyroid
14555 Telomeres and Vitamin D - many studies 82420
25 Jul, 2023 13:47
admin Genetics
15159 Ischemic Stroke is 18% more likely if poor Vitamin D genes (unless take more Vitamin D) – Feb 2024 57505
21 Mar, 2024 11:37
admin Genetics
7403 Health problems that run in families are often associated with low vitamin D 27920
20 Aug, 2023 15:34
admin Health
Top news
Vitamin D Receptor
Vit D Binding Protein
2269 Pharmacology of vitamin D - April 2011 23397
06 May, 2013 21:02
admin Health
Overview for doctors
3335 Vitamin D levels are strongly associated with genes: overview of twin studies – Nov 2012 21093
17 Dec, 2019 12:45
admin Genetics
Vitamin D Receptor
Vit D Binding Protein
1099 Blacks may not need as much Vitamin D (for their bones) 19783
07 Jul, 2018 10:56
admin Skin - Dark
Bone - Health

Articles in both Pregnancy and Genetics:

Articles in both Multiple Sclerosis and Genetics

Here are all 338 articles

Genes on the web

  • The Genes That Never Go Out of Style Sept 2018
    about 16% of all genes were known by 1991; that same 16% are the focus of half of all Genetics papers in 2015
    25% of all genes have never been the focus of a single scientific paper
    "Even supposedly game-changing techniques like CRISPR have altered the landscape of gene popularity very little"

Short URL= is.gd/vitdgenes

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5859 Genes not noticed.jpg admin 29 Aug, 2015 80.77 Kb 19173