Loading...
 
Toggle Health Problems and D

Risk of enveloped virus infection is increased 50 percent if poor Vitamin D Receptor - meta-analysis Dec 2018

Vitamin D Receptor polymorphisms and risk of enveloped virus infection: A meta-analysis
Gene. 2018 Dec 15;678:384-394. doi: 10.1016/j.gene.2018.08.017. Epub 2018 Aug 6.
Laplana M1, Royo JL2, Fibla J3.

  • 1 Dept of Basic Medical Sciences, University of Lleida and Institute of Biomedical Research of Lleida (IRBLleida), Lleida, Spain. marinalaplana at cmb.udl.cat.
  • 2 Dept of Basic Medical Sciences, University of Lleida and Institute of Biomedical Research of Lleida (IRBLleida), Lleida, Spain.
  • 3 Dept of Basic Medical Sciences, University of Lleida and Institute of Biomedical Research of Lleida (IRBLleida), Lleida, Spain. joan.fibla at cmb.udl.cat.
VitaminDWiki

Items in both categories Virus and Vitamin D Receptor are listed here:


The risk of 44 diseases at least double with poor Vitamin D Receptor as of Oct 2019

Vitamin D Receptor activation can be increased by any of: Resveratrol,  Omega-3,  MagnesiumZinc,   Quercetin,   non-daily Vit D,  Curcumin, intense exercise,   Ginger,   Essential oils, etc  Note: The founder of VitaminDWiki uses 10 of the 12 known VDR activators


15 most recently CHANGED items in Virus Category

Id Page Hits Last modification Creator Categories
11821 Nursing homes could reduce risk of COVID-19 with Vitamin D – June 30, 2020 183
14 Jul, 2020 21:30
admin Seniors
High Risk
Shut-in
Virus
11580 COVID-19 Coronavirus can most likely be fought by Vitamin D 244617
14 Jul, 2020 21:17
admin Virus
11842 COVID-19 antibodies mostly gone in 2 months (2 Chinese studies) – June 2020 17
14 Jul, 2020 20:30
admin Virus
11728 COVID-19 treated by Vitamin D - studies, reports, videos 6344
14 Jul, 2020 13:46
admin Virus
11727 COVID-19 more frequent and deadly for those with dark skins (high risk of low vitamin D) 2420
14 Jul, 2020 12:39
admin Skin - Dark
Virus
11840 Covid-19, T cells, and Vitamin D 110
13 Jul, 2020 20:24
admin Immunity
Virus
11838 COVID-19 linked to low vitamin D in 6 of 7 PubMed studies (as of April) – June 2020 97
11 Jul, 2020 16:41
admin Virus
11837 COVID-19 might be treated with Mg IV and Potassium – July 2020 69
11 Jul, 2020 14:26
admin Vitamin D and Magnesium
Virus
11833 Vitamin D and COVID-19 - VitaminD3World - July 2020 96
07 Jul, 2020 17:35
admin Virus
11828 Risk of dying of COVID-19 was 3.7 X higher if less than 8 ng of VItamin D - Mexico May 2020 233
07 Jul, 2020 15:26
admin Virus
11827 ICU was 2X less likely for COVID-19 hospitalization if Vitamin D more than 20 ng – July 2020 111
06 Jul, 2020 11:09
admin Trauma and surgery
Virus
11766 Fight COVID-19 with Vitamin D, Vitamin C, Zinc, Selenium, Resveratrol, etc. - Sardi May 12, 2020 874
05 Jul, 2020 16:46
admin Virus
Zinc
Resveratrol
11682 Reduce Coronavirus risk with Vitamin D (50,000 IU once a week) 5806
05 Jul, 2020 01:24
admin Virus
11823 COVID-19 deaths strongly correlated with percent having less than 10 ng of Vitamin D in a country– July 1 2020 148
04 Jul, 2020 19:49
admin Virus
11736 COVID-19 was 19X more likely if low vitamin D (may be invalid data)– April 2020 6169
04 Jul, 2020 14:17
admin Virus

 Download the PDF from Sci-Hub via VitaminDWiki
Image

Image

INTRODUCTION:
Vitamin-D plays a role regulating the immune response against to viral infection. In this sense, vitamin-D deficiency may confer increased susceptibility to enveloped virus infection such as

  • HIV,
  • Hepatitis,
  • Dengue and
  • Respiratory Syncytial virus infection, among others.

Vitamin D activity is mediated by its receptor (VDR), which acts as a transcription factor modulating the expression of genes triggering the response against viruses. To date, six major VDR polymorphisms (Cdx, A1012G, FokI, BsmI, ApaI and TaqI) have been studied in the context of viral infection susceptibility. Reported studies show controversial results probably due to statistical lack of power and population genetic differences.

AIMS: To do a systematic review of the published data and to perform a meta-analysis examining the role of six VDR polymorphisms on infection susceptibility to enveloped virus.

RESULTS: From all markers and virus considered an association of FokI polymorphism with RSV infection emerges as significant. The worldwide distribution of risk T-allele reveals a lower prevalence in African populations that runs parallel with the relative lower incidence of RSV-associated severe ALRI in children <1 year described in African samples.

CONCLUSION: The results disclose FokI polymorphism as a relevant variant capturing the association of VDR polymorphisms with viral infection.


Created by admin. Last Modification: Tuesday March 10, 2020 10:03:09 GMT-0000 by admin. (Version 8)

Attached files

ID Name Comment Uploaded Size Downloads
13441 VDR RSV.jpg admin 03 Feb, 2020 21:21 26.59 Kb 692
13440 VDR vs Virus.jpg admin 03 Feb, 2020 21:21 29.35 Kb 699
13439 VDR Enveloped.pdf PDF 2018 admin 03 Feb, 2020 21:21 6.01 Mb 125
See any problem with this page? Report it (FINALLY WORKS)