Many studies show that cardiovascular problems are treated & prevented by Vitamin D
As with many other health problems:
More Vitamin D is needed to treat than to prevent
Omega-3, Magnesium, and Vitamin K2 also probably also help
(More Cardiovascular info below this box)
Learn how Vitamin D is essential for good health
Watch a 5 minute video "Does Less Sun Mean more Disease?"
Browse for other Health Problems and D in left column or here
see also Supplementing and More in the menu at the top of very page
Cardiovascular category listing has 368 items along with related searches
368 items In Cardiovascular category
- Overview Cardiovascular and vitamin D
- Hypertension and vitamin D
- Overview Metabolic Syndrome and vitamin D
- Overview Stroke and vitamin D
- Heart Attack 326 items as of March 2017
- Arrhythmia OR “atrial fibrillation” 215 items as of Oct 2017
- (Arrhythmia OR “atrial fibrillation”) AND Magnesium 101 items as of Sept 2016
- "C-Reactive Protein" 499 items as of March 2017
- TRIGLYCERIDES 421 items as of March 2017
- "Peripheral Artery Disease" 81 items as of Oct 2017
- "Sudden Cardiac Arrest" 35 items as of March 2017
- Search VitaminDWiki for CHF or "HEART FAILURE" 1220 items as of Aug 2017
- Search VitaminDWiki for Atherosclerosis 726 items as of Oct 2017
- Cholesterol is needed to produce both Vitamin D and Cortisol
- Overview Cholesterol and vitamin D
- Statins and vitamin D statins often reduce levels of vitamin D
See also VitaminDWiki: Cardiovascular - general
- Low Vitamin K2 is as risky as smoking for heart disease - Oct 2016
- Yet another heart problem, Cardiac X syndrome, is associated with low vitamin D – 2016
- 800 IU of vitamin D is not enough to help Cardiovascular Disease (found again) – Oct 2016
- Peripheral Arterial Disease 2 percent more likely for every 1 nanogram less Vitamin D – Sept 2016
- Atrial Fibrillation 1.3 times more likely if low vitamin D – meta-analysis Sept 2016
- Chronic Heart Failure improved with 4,000 IU daily for a year – RCT April 2016
- Major heart problems avoided if have high vitamin D – 234,000 people Nov 2015
- Cardiovascular Disease and Diabetes helped by Vitamin D – most 2013-15 studies agree
- Cardiovascular Diseases and Vitamin D – Review Feb 2015
- Vitamin D is not a cardiovascular fad like Vitamins C, E, Folic Acid, selenium, beta-caroteen, etc. – Circulation Nov 2013
- More blood was pumped by those getting 800,000 IU of vitamin D after heart failure – RCT Oct 2013
- Sudden cardiac arrest 6X worse outcome if low vitamin D – Nov 2014
- Coronary artery disease extent is associated with extent of vitamin D deficiency – April 2014
- Chronic Heart Failure helped with 2,000 IU of vitamin D (PRA reduced) – RCT June 2013
- 92 percent had low vitamin D before heart surgery– Oct 2014
- Higher vitamin D levels associated with fewer vein clots decades later– Jan 2013
- Major Heart attacks occur 40 percent more often if vitamin D lower than 7 ng – Feb 2013
- Congestive Heart Failure patients helped with Vitamin D intervention – May 2013
- Inflammatory diseases: review of vitamin D, with many tables – May 2014 which has CVD summary tables
Pages listed in BOTH the categories Vitamin K and Cardiovascular
-
Mortality associated with Vitamin K insufficiency (PREVEND Study) – Nov 2017
-
Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017
-
Decalcify Aortic Valve – 3 year trial with 1 mg of Vitamin K and 5,000 IU of Vitamin D – 2021
-
Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
-
Athletes maximal cardiac output increased 12 percent with Vitamin K2 – RCT July 2017
-
Fast blood flow 6.8 X more likely if high vitamin D AND high vitamin K – Aug 2017
-
Low Vitamin K2 is as risky as smoking for heart disease - Oct 2016
-
Cardiovascular death: 9 percent due to hypertension or air pollution, 7 percent: low Vitamin K2 or smoking – Oct 2016
-
Decreased need for warfarin after Vitamin D levels optimized – RCT May 2016
-
Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
-
If you must take statins and want to avoid hardening of arteries, take vitamin K2 – RCT May 2015
-
Vitamin K2 decreases arterial stiffness (cleans arteries) – RCT Feb 2015
-
Hypothesis: Vitamin K will reduce prostate blood vessel problems – Jan 2015
-
Increased Vitamin K2 reduces the problems of excess Calcium – Nov 2013
-
Cholesterol, Vitamins D3 and K2, heart disease, sulfates, LDL, – Masterjohn Interview Jan 2013
-
Soft Bones, Hard Arteries, Vitamin D, Vitamin K2 and antibiotics – Sept 2012
-
Vitamin D – vitamin K – bittle bones – hardened arteries – LEF Sept 2010
Pages listed in BOTH the categories MORTALITY and Cardiovascular
-
Mortality associated with Vitamin K insufficiency (PREVEND Study) – Nov 2017
-
7X increased chance of death if coronary artery disease and low vitamin D – Oct 2013
-
Fewer heart attacks, hip fractures and deaths if more skin cancer – Sept 2013
-
Vitamin D protects against many types of health problems – review May 2013
-
Almost 6X more likely to die after coronary bypass if vitamin D deficient – Dec 2012
-
Predicted cardiac surgery death associated with low vitamin D levels – Dec 2012
-
3 X increased chance of death if have asthma – study of 200,000 people over 10 years – Nov 2012
-
Low levels of vitamin D associated with all cause mortality – Oct 2012
-
Death in less than 2 years of Heart Failure associated with low vitamin D - April 2012
-
Heart Failure early death 2X more likely if less than 20 nanograms of vitamin D – June 2012
-
Chance of death after heart failure reduced by 1000 IU of vitamin D – Feb 2012
-
Heart patients 10 percent more likely to die for every 4 ng less vitamin D – May 2011
-
Did not find association between vitamin D and cardiovascular mortality – Sept 2010
-
Table of outcomes for seniors vs vitamin D level
All items in Mortality and vitamin D (not just Cardio) 153 items
See also in VitaminDWiki HYPERTENSION
- Hypertension and vitamin D Overview
- Heart disease 2.9 X more likely if essential hypertension person has low vitamin D – Jan 2016
- All items in category Hypertension
115 items
Pages listed in BOTH the categories Hypertension and Cardiovascular
-
Hypothesis - Dysfunction of Autonomic Nervous System is associated with low vitamin D – April 2017
-
Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
-
Heart disease 2.9 X more likely if essential hypertension person has low vitamin D – Jan 2016
-
Major heart problems avoided if have high vitamin D – 234,000 people Nov 2015
-
Cardiovascular Disease and vitamin D – no proof yet – Sept 2015
-
Cardiovascular Diseases and Vitamin D – Review Feb 2015
-
Hypertension experts want still more vitamin D proof – Oct 2012
-
Vitamin D accounts for 25 percent of the racial differences in blood pressure – Oct 2011
See also in VitaminDWiki STROKES
- OVERVIEW of strokes
- All items in category Strokes and Vitamin D
65 items
Items in BOTH of the categories Cardiovascular and Stroke:
-
Stroke or coronary heart disease deaths 30% less likely if had taken more than 440 IU of vitamin D (900,000 patient years) – Jan 2018
-
Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017
-
Major heart problems avoided if have high vitamin D – 234,000 people Nov 2015
-
Cardiovascular Disease and vitamin D – no proof yet – Sept 2015
-
Links between Vitamin D Deficiency and Cardiovascular Diseases – April 2015
-
Cardiovascular Diseases and Vitamin D – Review Feb 2015
-
Low vitamin D is a risk factor for vascular diseases in African Americans - Aug 2012
See also in VitaminDWiki Metabolic Syndrome
Note Metabolic Syndrome = a combination of medical disorders which together increase the risk of developing cardiovascular disease and diabetes.
- Metabolic Syndrome and vitamin D
- All items in category Metabolic Syndrome and Vitamin D
64 items
- Sudden death 6X more likely with Metabolic Syndrome and low vitamin D – March 2012
Items in BOTH of the categories Cardiovascular and Metabolic Syndrome:
-
Cardiometabolic risk reduced by Omega-3 - dissertation Sept 2017
-
High maternal vitamin D resulted in 12 percent less inflammation (CRP) 20 years later – Oct 2016
-
Psoriasis is associated with kidney disease, heart problems, diabetes, etc – Nov 2015
-
More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
-
Links between Vitamin D Deficiency and Cardiovascular Diseases – April 2015
-
Review of role of Vitamin D in Cardiometabolic diseases – Jan 2013
-
1000 IU vitamin D did not reduce cardiovascular risk factors – Aug 2012
-
High triglycerides in Metabolic Syndrome associated with low Vitamin D – July 2012
-
Overview Metabolic Syndrome and vitamin D
See also web
- Cardiovascular benefits of vitamin D - Feb 2014, PDF is attached at the bottom of this page
- Arrhythmias in chronic kidney disease 2011
- Arrhythmias Life Extension date unknown - perhaps 2011
"Food, drugs, and medications. Coffee, tea, chocolate, red wine, or simply overeating may cause rapid heartbeats that may be frightening when felt but are rarely serious"
"Both magnesium and potassium are intricately involved in the heart’s electrical stability (Cybulski J et al 2004); consequently, maintaining normal functional blood levels and ratios of each is important"
- More plaque in monkey coronary arteries having less vitamin D receptors April 2012
- Vitamin D status decline during heart surgery linked to bypass machine Vitamin D Council $5 paywall July 2013
Far less decrease in vitamin D levels in children who did not use the bypass machine.
Wonder about adults as well
- How does vitamin D help heart health? Vitamin D Council Feb 2014
Links to previous blogs on Cardiovascular problems and Vitamin D
Brief review of Renin angiotensin system (RAS); Vascular smooth muscle cells (VSMC); Insulin resistance; Atherosclerosis; Endothelial dysfunction; Cytokines
- Vitamin D deficiency is independently associated with the extent of coronary artery disease May 2014
Deficiency associated with 30% more CAD risk, especially if Vitamin D < 10 ng
- Cholesterol-Slashing Drug Can Protect High-Risk Heart Patients, Study Finds NYT March 2017
Cost of $14,523/year. "Number needed to treat" with Repatha appears to be 69
Number Needed to Treat appears to be 5 - just 800 IU of Vitamin D - for approximately $5 per year
- CVD 2X more prevalent in Korea for those with less than 10 ng of vitamin D May 2012
6,000 people over the age of 50. Full text on-line
Vitamin D Council on related topics
MAYO Clinic April 2012: Pathways from vitamin D Deficiency to CVD
The effect of vitamin D status on risk factors for cardiovascular disease Nature 2013
$4 to rent the PDF - but the following chart from the study is on Google images
Random controlled trial found NO HEART FAILURE BENEFIT with 50,000 IU weekly - Feb 2013 - strange
A randomized controlled trial of high dose vitamin D3 in patients with heart failure.
JACC Heart Fail. 2013 Feb;1(1):84-90. doi: 10.1016/j.jchf.2012.11.003.
Boxer RS1, Kenny AM2, Schmotzer BJ3, Vest M4, Fiutem JJ5, Piña IL6.
OBJECTIVE: To investigate the effect of Vitamin D3 on physical performance in patients with HF.
BACKGROUND: HF is associated with functional decline and frailty. Vitamin D deficiency is associated with loss of muscle strength and poor outcomes in patients with HF.
METHODS: Sixty-four patients participated in a 6-month parallel design double blind RCT to test the hypothesis that oral vitamin D3 would improve physical performance. Vitamin D3 50,000 IU or placebo was given weekly; all received daily calcium. Patients were included regardless of EF and 25OHD ≤ 37.5 ng/ml. The primary outcome was peak VO2, and secondary outcomes were the 6MW, TGUG and knee isokinetic muscle strength. Between group comparisons were made using ANCOVA models that adjust for baseline measures.
RESULTS: Patients were age 65.9 ± 10.4 years old, 48% women, 64% African American, EF 37.6±13.9, 36% NYHA III, the remainder NYHA II.
At baseline the vitamin D group 25OHD was 19.1 ± 9.3 ng/ml and increased to 61.7 ± 20.3 ng/ml; in the placebo group baseline 25OHD was 17.8 ± 9.0 ng/ml and decreased to 17.4 ± 9.8 ng/ml at 6 months (between groups p<0.001).
There was no significant change from baseline to 6 months in peak VO2, 6MW, TGUG or isokinetic muscle strength.
CONCLUSIONS: Vitamin D3 did not improve physical performance for patients with HF despite a robust increase in serum 25OHD.
Vitamin D repletion in patients with HF should conform to standard adult guidelines for vitamin D supplementation.
PMID: 24614995
 Download the PDF from VitaminDWiki.
Strange - seems like the study did things correctly.Good amount of vitamin D, trial lasted long enough, vitamin D levels were raised high enough. Yet no benefit.
INTERVENTION Clinical Trials for (heart OR cardiovascular) and "vitamin D" 265 as of Jan 2017
- Intervention = give vitamin D and see what happens usually testing vitamin D vs placebo
- The majority of these intervention trials are for TREATMENT, rather than prevention
- Vitamin D and cardiovascular disease preventiom May 2016
Large Ongoing Random Controlled CVD trials
No apparent attempt to trial those with low levels of vitamin D,
No Magnesium added,
No Omega-3 added,
Not much vitamin D used - especially since statins used with CVD reduce the vitamin D
No Vitamin K2 to stop Calcium increased by Vitamin D from coating the arteries
83 proofs that Vitamin D works (as of Aug 2017)
Proof that Vitamin D Works has the following Cardio related proofs
Health Problem Treat
Prevent Reduction
click for details RCT = Random Controlled Trial
* = link to additional RCT
CT = Clinical Trial Vitamin
DWiki
#
Hypertension T 149 to 142 mm Hg RCT* *, 2400 IU. 100,000 IU* 1
Cardiovascular after attack T 32 % fewer deaths CT 1000 IU 2
Diabetes T2 T 62 % RCT* *, CRP reduction, 4000 IU 4
Congestive Heart Failure T 90 % RCT, 1000 IU infants (also: Adults, not RCT) 27
After Heart Attack T __ +6% ejection fraction RCT, 800,000 IU one time 34
See also: Omega-3
- Mayo Clinic on methods of dealing with Afib April 2013 at the bottom of this page Includes Vitamin D and Omega-3
- Overview: Omega-3 many benefits include helping vitamin D
- LA Times review of Fish Oil Meta-analysis April 2012
Clinical studies in recent decades have not shown that taking Fish Oil reduces chance of heart attack
Wonder - is it perhaps because you need fish oil AND vitamin D, and many people are now have low vitamin D levels?
CLICK HERE for the meta-analysis study
Items in BOTH of the categories Cardiovascular and Omega-3:
-
Another Nail in the Coffin for Fish Oil Supplements (nope) – JAMA April 2018
-
Omega-3 provides many cardiovascular benefits – April 2018
-
Omega-3 helps the heart, AHA class II recommendation, more than 1 gm may be needed – March 2018
-
3 days of Omega-3 before cardiac surgery reduced risk of post-op bleeding by half – RCT March 2018
-
Perhaps the Omega-3 optimal level is 10 percent, not 8 – Feb 2018
-
Omega-3 Cardiovascular meta-analysis has at least 5 major problems – Jan 2018
-
Benefits of Omega-3 beyond heart health - LEF Feb 2018
-
Higher Omega-3 index (4 to 8 percent) associated with 30 percent less risk of coronary disease (10 studies) July 2017
-
Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
-
Omega-3 reduced time in hospital and atrial fibrillation after cardiac surgery – meta-analysis May 2016
-
For every Omega-3 dollar there is a 84 dollar savings in Cardiovascular costs - Foster and Sullivan April 2016
-
High dose Omega-3 probably reduces heart problems – American Heart Association – March 2017
-
Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis Dec 2016
-
Omega-3 – need more than 1 gram for a short time to reduce Cardiovascular Disease – Nov 2016
-
Omega-3 is vital for health, mail-in test is low cost and accurate
-
Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
-
Atrial fibrillation sometimes treated by Omega-3 – meta-analysis Sept 2015
-
Salmon intervention (vitamin D and Omega-3) improved heart rate variability and reduced anxiety – Nov 2014
-
Omega-7 - in addition to Omega-3
-
Omega-3 reduces Coronary Heart Disease - infographic June 2014
-
Cardiovascular diseases – conflicting data on benefits of Omega-3 and vitamin D – Feb 2014
-
Cardiovascular system benefits from both Omega-3 and vitamin D – Dec 2012
-
Omega-3 does not help heart patients – meta-analysis Sept 2012
Items in BOTH of the categories Cardiovascular and Magnesium:
-
Cardiometaboic problems decreased with increased Vitamin D, unless low Magnesium – Aug 2017
-
Heart problems in obese increase if deficient in BOTH Vitamin D and Magnesium – Aug 2017
-
Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis Dec 2016
-
Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
-
More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
-
Atrial Fibrillation - remineralize your heart - Aug 2015
-
Magnesium Suppresses Formation of Clogged Arteries - May 2014
-
Death from Coronary Heart Disease related to low Magnesium intake – March 2013
-
Magnesium prevents cardiovascular events – Meta-analysis March 2013
-
Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
-
Low Magnesium and Heart Attacks – associated for 40 years – Nov 2012
- See also book on Amazon:Atrial Fibrillation: Remineralize Your Heart Dr. Dean July 2015
$3. has gotten many 5 star reviews
Short url = http://bit.ly/Zczfrw
Overview Cardiovascular and vitamin D
45828 visitors, last modified 17 Aug, 2017, URL:
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- Overview Cardiovascular and vitamin D
- Hypertension and vitamin D
- Overview Metabolic Syndrome and vitamin D
- Overview Stroke and vitamin D
- Heart Attack 326 items as of March 2017
- Arrhythmia OR “atrial fibrillation” 215 items as of Oct 2017
- (Arrhythmia OR “atrial fibrillation”) AND Magnesium 101 items as of Sept 2016
- "C-Reactive Protein" 499 items as of March 2017
- TRIGLYCERIDES 421 items as of March 2017
- "Peripheral Artery Disease" 81 items as of Oct 2017
- "Sudden Cardiac Arrest" 35 items as of March 2017
- Search VitaminDWiki for CHF or "HEART FAILURE" 1220 items as of Aug 2017
- Search VitaminDWiki for Atherosclerosis 726 items as of Oct 2017
- Cholesterol is needed to produce both Vitamin D and Cortisol
- Overview Cholesterol and vitamin D
- Statins and vitamin D statins often reduce levels of vitamin D
See also VitaminDWiki: Cardiovascular - general
- Low Vitamin K2 is as risky as smoking for heart disease - Oct 2016
- Yet another heart problem, Cardiac X syndrome, is associated with low vitamin D – 2016
- 800 IU of vitamin D is not enough to help Cardiovascular Disease (found again) – Oct 2016
- Peripheral Arterial Disease 2 percent more likely for every 1 nanogram less Vitamin D – Sept 2016
- Atrial Fibrillation 1.3 times more likely if low vitamin D – meta-analysis Sept 2016
- Chronic Heart Failure improved with 4,000 IU daily for a year – RCT April 2016
- Major heart problems avoided if have high vitamin D – 234,000 people Nov 2015
- Cardiovascular Disease and Diabetes helped by Vitamin D – most 2013-15 studies agree
- Cardiovascular Diseases and Vitamin D – Review Feb 2015
- Vitamin D is not a cardiovascular fad like Vitamins C, E, Folic Acid, selenium, beta-caroteen, etc. – Circulation Nov 2013
- More blood was pumped by those getting 800,000 IU of vitamin D after heart failure – RCT Oct 2013
- Sudden cardiac arrest 6X worse outcome if low vitamin D – Nov 2014
- Coronary artery disease extent is associated with extent of vitamin D deficiency – April 2014
- Chronic Heart Failure helped with 2,000 IU of vitamin D (PRA reduced) – RCT June 2013
- 92 percent had low vitamin D before heart surgery– Oct 2014
- Higher vitamin D levels associated with fewer vein clots decades later– Jan 2013
- Major Heart attacks occur 40 percent more often if vitamin D lower than 7 ng – Feb 2013
- Congestive Heart Failure patients helped with Vitamin D intervention – May 2013
- Inflammatory diseases: review of vitamin D, with many tables – May 2014 which has CVD summary tables
Pages listed in BOTH the categories Vitamin K and Cardiovascular
- Mortality associated with Vitamin K insufficiency (PREVEND Study) – Nov 2017
- Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017
- Decalcify Aortic Valve – 3 year trial with 1 mg of Vitamin K and 5,000 IU of Vitamin D – 2021
- Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
- Athletes maximal cardiac output increased 12 percent with Vitamin K2 – RCT July 2017
- Fast blood flow 6.8 X more likely if high vitamin D AND high vitamin K – Aug 2017
- Low Vitamin K2 is as risky as smoking for heart disease - Oct 2016
- Cardiovascular death: 9 percent due to hypertension or air pollution, 7 percent: low Vitamin K2 or smoking – Oct 2016
- Decreased need for warfarin after Vitamin D levels optimized – RCT May 2016
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- If you must take statins and want to avoid hardening of arteries, take vitamin K2 – RCT May 2015
- Vitamin K2 decreases arterial stiffness (cleans arteries) – RCT Feb 2015
- Hypothesis: Vitamin K will reduce prostate blood vessel problems – Jan 2015
- Increased Vitamin K2 reduces the problems of excess Calcium – Nov 2013
- Cholesterol, Vitamins D3 and K2, heart disease, sulfates, LDL, – Masterjohn Interview Jan 2013
- Soft Bones, Hard Arteries, Vitamin D, Vitamin K2 and antibiotics – Sept 2012
- Vitamin D – vitamin K – bittle bones – hardened arteries – LEF Sept 2010
Pages listed in BOTH the categories MORTALITY and Cardiovascular
- Mortality associated with Vitamin K insufficiency (PREVEND Study) – Nov 2017
- 7X increased chance of death if coronary artery disease and low vitamin D – Oct 2013
- Fewer heart attacks, hip fractures and deaths if more skin cancer – Sept 2013
- Vitamin D protects against many types of health problems – review May 2013
- Almost 6X more likely to die after coronary bypass if vitamin D deficient – Dec 2012
- Predicted cardiac surgery death associated with low vitamin D levels – Dec 2012
- 3 X increased chance of death if have asthma – study of 200,000 people over 10 years – Nov 2012
- Low levels of vitamin D associated with all cause mortality – Oct 2012
- Death in less than 2 years of Heart Failure associated with low vitamin D - April 2012
- Heart Failure early death 2X more likely if less than 20 nanograms of vitamin D – June 2012
- Chance of death after heart failure reduced by 1000 IU of vitamin D – Feb 2012
- Heart patients 10 percent more likely to die for every 4 ng less vitamin D – May 2011
- Did not find association between vitamin D and cardiovascular mortality – Sept 2010
- Table of outcomes for seniors vs vitamin D level
See also in VitaminDWiki HYPERTENSION
- Hypertension and vitamin D Overview
- Heart disease 2.9 X more likely if essential hypertension person has low vitamin D – Jan 2016
- All items in category Hypertension
115 items Pages listed in BOTH the categories Hypertension and Cardiovascular
- Hypothesis - Dysfunction of Autonomic Nervous System is associated with low vitamin D – April 2017
- Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
- Heart disease 2.9 X more likely if essential hypertension person has low vitamin D – Jan 2016
- Major heart problems avoided if have high vitamin D – 234,000 people Nov 2015
- Cardiovascular Disease and vitamin D – no proof yet – Sept 2015
- Cardiovascular Diseases and Vitamin D – Review Feb 2015
- Hypertension experts want still more vitamin D proof – Oct 2012
- Vitamin D accounts for 25 percent of the racial differences in blood pressure – Oct 2011
See also in VitaminDWiki STROKES
- OVERVIEW of strokes
- All items in category Strokes and Vitamin D
65 items Items in BOTH of the categories Cardiovascular and Stroke:
- Stroke or coronary heart disease deaths 30% less likely if had taken more than 440 IU of vitamin D (900,000 patient years) – Jan 2018
- Intracranial arterial calcification in 85 percent of ischemic strokes (Vitamin K and Vitamin D should help) – Oct 2017
- Major heart problems avoided if have high vitamin D – 234,000 people Nov 2015
- Cardiovascular Disease and vitamin D – no proof yet – Sept 2015
- Links between Vitamin D Deficiency and Cardiovascular Diseases – April 2015
- Cardiovascular Diseases and Vitamin D – Review Feb 2015
- Low vitamin D is a risk factor for vascular diseases in African Americans - Aug 2012
See also in VitaminDWiki Metabolic Syndrome
Note Metabolic Syndrome = a combination of medical disorders which together increase the risk of developing cardiovascular disease and diabetes.
- Metabolic Syndrome and vitamin D
- All items in category Metabolic Syndrome and Vitamin D
64 items - Sudden death 6X more likely with Metabolic Syndrome and low vitamin D – March 2012
Items in BOTH of the categories Cardiovascular and Metabolic Syndrome:
- Cardiometabolic risk reduced by Omega-3 - dissertation Sept 2017
- High maternal vitamin D resulted in 12 percent less inflammation (CRP) 20 years later – Oct 2016
- Psoriasis is associated with kidney disease, heart problems, diabetes, etc – Nov 2015
- More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
- Links between Vitamin D Deficiency and Cardiovascular Diseases – April 2015
- Review of role of Vitamin D in Cardiometabolic diseases – Jan 2013
- 1000 IU vitamin D did not reduce cardiovascular risk factors – Aug 2012
- High triglycerides in Metabolic Syndrome associated with low Vitamin D – July 2012
- Overview Metabolic Syndrome and vitamin D
See also web
- Cardiovascular benefits of vitamin D - Feb 2014, PDF is attached at the bottom of this page
- Arrhythmias in chronic kidney disease 2011
- Arrhythmias Life Extension date unknown - perhaps 2011
"Food, drugs, and medications. Coffee, tea, chocolate, red wine, or simply overeating may cause rapid heartbeats that may be frightening when felt but are rarely serious"
"Both magnesium and potassium are intricately involved in the heart’s electrical stability (Cybulski J et al 2004); consequently, maintaining normal functional blood levels and ratios of each is important" - More plaque in monkey coronary arteries having less vitamin D receptors April 2012
- Vitamin D status decline during heart surgery linked to bypass machine Vitamin D Council $5 paywall July 2013
Far less decrease in vitamin D levels in children who did not use the bypass machine.
Wonder about adults as well - How does vitamin D help heart health? Vitamin D Council Feb 2014
Links to previous blogs on Cardiovascular problems and Vitamin D
Brief review of Renin angiotensin system (RAS); Vascular smooth muscle cells (VSMC); Insulin resistance; Atherosclerosis; Endothelial dysfunction; Cytokines - Vitamin D deficiency is independently associated with the extent of coronary artery disease May 2014
Deficiency associated with 30% more CAD risk, especially if Vitamin D < 10 ng - Cholesterol-Slashing Drug Can Protect High-Risk Heart Patients, Study Finds NYT March 2017
Cost of $14,523/year. "Number needed to treat" with Repatha appears to be 69
Number Needed to Treat appears to be 5 - just 800 IU of Vitamin D - for approximately $5 per year - CVD 2X more prevalent in Korea for those with less than 10 ng of vitamin D May 2012
6,000 people over the age of 50. Full text on-line
Vitamin D Council on related topics
MAYO Clinic April 2012: Pathways from vitamin D Deficiency to CVD
The effect of vitamin D status on risk factors for cardiovascular disease Nature 2013
$4 to rent the PDF - but the following chart from the study is on Google images
Random controlled trial found NO HEART FAILURE BENEFIT with 50,000 IU weekly - Feb 2013 - strange
A randomized controlled trial of high dose vitamin D3 in patients with heart failure.
JACC Heart Fail. 2013 Feb;1(1):84-90. doi: 10.1016/j.jchf.2012.11.003.
Boxer RS1, Kenny AM2, Schmotzer BJ3, Vest M4, Fiutem JJ5, Piña IL6.OBJECTIVE: To investigate the effect of Vitamin D3 on physical performance in patients with HF.
BACKGROUND: HF is associated with functional decline and frailty. Vitamin D deficiency is associated with loss of muscle strength and poor outcomes in patients with HF.
METHODS: Sixty-four patients participated in a 6-month parallel design double blind RCT to test the hypothesis that oral vitamin D3 would improve physical performance. Vitamin D3 50,000 IU or placebo was given weekly; all received daily calcium. Patients were included regardless of EF and 25OHD ≤ 37.5 ng/ml. The primary outcome was peak VO2, and secondary outcomes were the 6MW, TGUG and knee isokinetic muscle strength. Between group comparisons were made using ANCOVA models that adjust for baseline measures.
RESULTS: Patients were age 65.9 ± 10.4 years old, 48% women, 64% African American, EF 37.6±13.9, 36% NYHA III, the remainder NYHA II.
At baseline the vitamin D group 25OHD was 19.1 ± 9.3 ng/ml and increased to 61.7 ± 20.3 ng/ml; in the placebo group baseline 25OHD was 17.8 ± 9.0 ng/ml and decreased to 17.4 ± 9.8 ng/ml at 6 months (between groups p<0.001).
There was no significant change from baseline to 6 months in peak VO2, 6MW, TGUG or isokinetic muscle strength.CONCLUSIONS: Vitamin D3 did not improve physical performance for patients with HF despite a robust increase in serum 25OHD.
Vitamin D repletion in patients with HF should conform to standard adult guidelines for vitamin D supplementation.PMID: 24614995
 Download the PDF from VitaminDWiki.Strange - seems like the study did things correctly.Good amount of vitamin D, trial lasted long enough, vitamin D levels were raised high enough. Yet no benefit.
INTERVENTION Clinical Trials for (heart OR cardiovascular) and "vitamin D" 265 as of Jan 2017
- Intervention = give vitamin D and see what happens usually testing vitamin D vs placebo
- The majority of these intervention trials are for TREATMENT, rather than prevention
- Vitamin D and cardiovascular disease preventiom May 2016
Large Ongoing Random Controlled CVD trials
No apparent attempt to trial those with low levels of vitamin D,
No Magnesium added,
No Omega-3 added,
Not much vitamin D used - especially since statins used with CVD reduce the vitamin D
No Vitamin K2 to stop Calcium increased by Vitamin D from coating the arteries
83 proofs that Vitamin D works (as of Aug 2017)
Proof that Vitamin D Works has the following Cardio related proofs
Health Problem Treat
PreventReduction
click for detailsRCT = Random Controlled Trial
* = link to additional RCT
CT = Clinical TrialVitamin
DWiki
#Hypertension T 149 to 142 mm Hg RCT* *, 2400 IU. 100,000 IU* 1 Cardiovascular after attack T 32 % fewer deaths CT 1000 IU 2 Diabetes T2 T 62 % RCT* *, CRP reduction, 4000 IU 4 Congestive Heart Failure T 90 % RCT, 1000 IU infants (also: Adults, not RCT) 27 After Heart Attack T __ +6% ejection fraction RCT, 800,000 IU one time 34
See also: Omega-3
- Mayo Clinic on methods of dealing with Afib April 2013 at the bottom of this page Includes Vitamin D and Omega-3
- Overview: Omega-3 many benefits include helping vitamin D
- LA Times review of Fish Oil Meta-analysis April 2012
Clinical studies in recent decades have not shown that taking Fish Oil reduces chance of heart attack
Wonder - is it perhaps because you need fish oil AND vitamin D, and many people are now have low vitamin D levels?
CLICK HERE for the meta-analysis study
Items in BOTH of the categories Cardiovascular and Omega-3:
- Another Nail in the Coffin for Fish Oil Supplements (nope) – JAMA April 2018
- Omega-3 provides many cardiovascular benefits – April 2018
- Omega-3 helps the heart, AHA class II recommendation, more than 1 gm may be needed – March 2018
- 3 days of Omega-3 before cardiac surgery reduced risk of post-op bleeding by half – RCT March 2018
- Perhaps the Omega-3 optimal level is 10 percent, not 8 – Feb 2018
- Omega-3 Cardiovascular meta-analysis has at least 5 major problems – Jan 2018
- Benefits of Omega-3 beyond heart health - LEF Feb 2018
- Higher Omega-3 index (4 to 8 percent) associated with 30 percent less risk of coronary disease (10 studies) July 2017
- Cardiovascular problems reduced by low dose aspirin and perhaps Omega-3 (also Vit K) – Sept 2017
- Omega-3 reduced time in hospital and atrial fibrillation after cardiac surgery – meta-analysis May 2016
- For every Omega-3 dollar there is a 84 dollar savings in Cardiovascular costs - Foster and Sullivan April 2016
- High dose Omega-3 probably reduces heart problems – American Heart Association – March 2017
- Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis Dec 2016
- Omega-3 – need more than 1 gram for a short time to reduce Cardiovascular Disease – Nov 2016
- Omega-3 is vital for health, mail-in test is low cost and accurate
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- Atrial fibrillation sometimes treated by Omega-3 – meta-analysis Sept 2015
- Salmon intervention (vitamin D and Omega-3) improved heart rate variability and reduced anxiety – Nov 2014
- Omega-7 - in addition to Omega-3
- Omega-3 reduces Coronary Heart Disease - infographic June 2014
- Cardiovascular diseases – conflicting data on benefits of Omega-3 and vitamin D – Feb 2014
- Cardiovascular system benefits from both Omega-3 and vitamin D – Dec 2012
- Omega-3 does not help heart patients – meta-analysis Sept 2012
Items in BOTH of the categories Cardiovascular and Magnesium:
- Cardiometaboic problems decreased with increased Vitamin D, unless low Magnesium – Aug 2017
- Heart problems in obese increase if deficient in BOTH Vitamin D and Magnesium – Aug 2017
- Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis Dec 2016
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
- Atrial Fibrillation - remineralize your heart - Aug 2015
- Magnesium Suppresses Formation of Clogged Arteries - May 2014
- Death from Coronary Heart Disease related to low Magnesium intake – March 2013
- Magnesium prevents cardiovascular events – Meta-analysis March 2013
- Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
- Low Magnesium and Heart Attacks – associated for 40 years – Nov 2012
- See also book on Amazon:Atrial Fibrillation: Remineralize Your Heart Dr. Dean July 2015
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Overview Cardiovascular and vitamin D
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