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Meta-analysis of Vitamin D

474 Meta-analyses

See also Overview Meta-analysis of Vitamin D
Unfortunately, a meta-analysis will frequently fail to consider one or more of the following

  1. Dose size (Some gave the same importance to 40 IU as 10,000 IU)
  2. Dose frequency (Some ignore differences between daily, weekly, monthly, and annual dosing)
  3. Duration, (Some gave same importance to 4 weeks as 4 years)
       It takes 3 to 12 months for vitamin D levels to come to a new plateau
       and it often takes months for the body to then utilize it
  4. Pre-existing Vitamin D blood level
       adding vitamin D does not provide much benefit if person alrady has a good level
  5. Cofactors (Most meta-analyses ignore the importance of Magnesium, Omega-3, Vitamin K2, etc)
  6. Type of Vitamin D - D3 far better than D2
  7. Those with poor guts need a different type of vitamin D
  8. Those who are Obese need 2.5 X more vitamin D
  9. Many drugs, such as statins deplete vitamin D or the Magnesium needed by Vitamin D
  10. For some health problems pulsed vitamin D, not daily, is far better (gets over possible Vitamin D receptor limitation)

See also Proof that Vitamin D Works

See also All items in category Intervention Vitamin D 636 items

See also Clinical Trials of vitamin D can have “biological flaws” – Jan 2015
See also Nice description of Meta-Analysis in Scientific American Jan 2014
See also The Misuse of Meta-analysis in Nutrition Research JAMA Sept 2017
". . . they have mixed apples and oranges—and sometimes “apples, lice, and killer whales”—yielding meaningless conclusions"
"In a 2007 review of 111 industry-funded (nutrition) studies, funding source was significantly related to study conclusions"

VitaminDWiki Comment on Scientific American article

It does not mention the major problems of Vitamin D Meta-analyses.
1) Dose sizes are ignored: Studies assume benefit from 400 IU is the same as for 4,000 IU
2) Durations are ignored: Studies assume benefit of 1 month dosing is the same as 1 year dosing
3) Existing Vitamin D levels are often ignored.
  Studies ignore that a 20 ng addition to a 10 ng person has vastly more benefit than a 20 ng addition to a 40 ng person
A rare example of a good meta-analysis is: one on depression - April 2014

Really great medical studies do not blindly give a single supplement/drug to a group, but rather treat the patients as individuals and provide extra Magnesium, Vitamin K2, Omega-3, Vitamin C, etc as needed. These studies, which have the best results, are not Random Controlled Trials and are virtually never included in a meta-analysis.

Likewise, the trials which give vitamin D to an entire country, or to all of the patients (immoral not to do so) are never considered by any meta-analysis

Vitamin D has climbed the pyramid for decades, but has not yet reached the top

Vitamin D Pyramid

International prospective register of on-going systematic reviews: 569 reviews of Vitamin D as of March 2020

PROSPERO

Intervention - Vitamin D includes the following:
Studies in VitaminDWiki

Year Randomized
Controlled
Trials
Interventions Meta-
analyses
2017- 4852
2016- 5140
2015698235
2014646348
2013816337
2012413839

Note: Govt recommendations in 2015 often ignored data after 2011

Table of contents

20 Most-visited pages in Meta-analysis category in VitaminDWiki

Id Page Hits Last modification Creator Categories
7021 Epileptic children have low levels of vitamin D – VitaminDWiki 27117
17 Mar, 2020 13:09
admin Overviews
Meta-analysis of Vitamin D
Category
Epilepsy
5913 Meta-analysis of Vitamin D 23732
14 Mar, 2020 10:58
admin Meta-analysis of Vitamin D
Category
3265 Alzheimer's Disease more likely with low vitamin D – meta-analysis Oct 2012 16983
13 Dec, 2015 23:20
admin Meta-analysis of Vitamin D
Top news
Cognitive
5322 Cancer survival 4 percent more likely with just a little more vitamin D (4 ng) - meta-analysis July 2014 15638
24 Feb, 2019 14:51
admin Mortality and D
Cancer - Colon
Cancer - Breast
Cancer
Meta-analysis of Vitamin D
Cancer - Lymphoma
3052 Cognitive Impairment 2.4X more likely if low vitamin D – meta-analysis July 2012 15081
21 Oct, 2016 09:53
admin Meta-analysis of Vitamin D
Top news
Cognitive
10573 Diabetic Foot Ulcer 3.2 X or 3.6 X more likely if low vitamin D – meta-analyses 2019 12881
28 Nov, 2019 11:36
admin Diabetes
Meta-analysis of Vitamin D
4808 Sports benefits from up to 50 ng of Vitamin – meta-analysis - Nov 2012 12201
04 Aug, 2020 16:30
admin Sports and Vitamin D
Meta-analysis of Vitamin D
Optimum
5252 Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014 11588
09 Oct, 2016 08:35
admin Depression
Meta-analysis of Vitamin D
Top news
4700 Elderly lower limb muscle strength improved with Vitamin D supplementation - Meta-analysis Oct 2013 11103
09 Mar, 2018 15:36
admin Seniors
Sports and Vitamin D
Meta-analysis of Vitamin D
4213 Vitamin D and Respiratory Tract Infections – meta-analysis with charts June 2013 11001
23 Jan, 2018 18:40
admin Breathing
Meta-analysis of Vitamin D
Inflammation
4936 Parkinson’s Disease and the “Sunshine” Vitamin (vitamin D) – July 2013 10722
08 Jan, 2018 10:13
admin Parkinson
Meta-analysis of Vitamin D
4267 Overview Meta-analysis of Vitamin D 9835
08 Jul, 2019 00:53
admin Overviews
Meta-analysis of Vitamin D
4651 Vitamin D deficiency diseases in dark skinned people living far from equator – Meta-analysis Oct 2013 9685
01 Feb, 2017 16:40
admin Skin - Dark
Rickets
Vitamin D Far from equator
Meta-analysis of Vitamin D
Top news
2979 Low vitamin D increased probability of low birth weight by 60 percent – meta-analysis June 2012 9596
13 Dec, 2016 18:39
admin Pregnancy
Meta-analysis of Vitamin D
Top news
7053 Chronic Widespread Pain associated with Vitamin D under 10 ng – meta-analysis Oct 2015 9469
12 Dec, 2015 00:28
admin Pain - chronic
Meta-analysis of Vitamin D
3044 Shift workers 23 percent more likely to have cardiovascular events – meta-analysis July 2012 9230
11 Nov, 2015 01:57
admin Cardiovascular
Meta-analysis of Vitamin D
High Risk
3445 Acute respiratory infection treated by vitamin D in 6 of 12 clinical trials – review Nov 2012 8997
10 Aug, 2020 17:48
admin Breathing
Meta-analysis of Vitamin D
Top news
5679 Vitamin D supplementation improves muscle strength in healthy adults – meta-analysis of 6 RCT Aug 2014 8822
11 Nov, 2019 16:08
admin Sports and Vitamin D
Meta-analysis of Vitamin D
3941 2X more preeclampsia when vitamin D less than 30 ng, etc. - meta-analysis March 2013 8546
16 Jan, 2016 02:59
admin Pregnancy
Meta-analysis of Vitamin D
Hypertension
6003 1.5X increased infection, sepsis, and death if in ICU with low vitamin D - Meta-analysis Dec 2014 8325
20 Oct, 2015 13:33
admin Trauma and surgery
Meta-analysis of Vitamin D

The Meta-analysis of Autism and Vitamin D

2

The Meta-analysis of BREATHING and Vitamin D

See also PubMed: Vitamin D and asthma in children: A systematic review and meta-analysis of observational studies
July 2017 3.4X more often in low vitamin D


The Meta-analysis of CANCER and Vitamin D

The Meta-analysis of Breast Cancer and Vitamin D

The Meta-analysis of Bladder Cancer and Vitamin D

The Meta-analysis of Colon Cancer and Vitamin D

The Meta-analysis of Prostate Cancer and Vitamin D

The Meta-analysis of Cardiovascular and Vitamin D

See also PubMed (behind paywallSerum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies
April 2017, 34 publications with 180,667 participants, 10% less likely for each 10ng higher level of vitamin D


The Meta-analysis of Cognition and Vitamin D

The Meta-analysis of Depression AND Vitamin D

The Meta-analysis of Diabetes and Vitamin D

The Meta-analysis of Falls/Fractures

The Meta-analysis of Gut and Vitamin D 

The Meta-analysis of Hypertension and Vitamin D

The Meta-analysis of Infant-Child and Vitamin D

The Meta-analysis of Inflammation and Vitamin D

The Meta-analysis of Kidney and Vitamin D 

The Meta-analysis of Loading Dose of Vitamin D

The Meta-analysis of Mortality and Vitamin D

The Meta-analysis of Multiple Sclerosis and Vitamin D

The Meta-analysis of Obesity and Vitamin D

The Meta-analysis of Pregnancy and Vitamin D

See also PubMed: Pregnancy outcome and ultraviolet radiation; A systematic review May 2017 Free PDF online


The Meta-analysis of Psoriasis and Vitamin D (see also Skin)

The Meta-analysis of Rheumatoid Arthritis and Vitamin D

The Meta-analysis of Seniors and Vitamin D

The Meta-analysis of Sports and Vitamin D

See also PubMed 3,000 IU of vitamin D for 12 weeks did not help Sports Performance - Meta-analysis June 2017

The Meta-analysis of Stroke and Vitamin D

The Meta-analysis of Trauma/Surgery and Vitamin D

The Meta-analysis of Tuberculosis and Vitamin D (see also Breathing)

The Meta-analysis of Vitamin D Receptor

All of the articles in Meta-Analysis - sorted by date


Short URL =https://is.gd/MetaD

Meta-analysis of Vitamin D        
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