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Yet another reason to take Vitamin D while pregnant – fight COVID - meta-analysis May 2023

The Vitamin D Serum Levels in Pregnant Women Affected by COVID-19: A Systematic Review and Meta-Analysis

Nutrients Volume 15 Issue 11 10.3390/nu15112588
Luiza Szarpak 1,Stepan Feduniw 2,3,*ORCID,Michal Pruc 1,4ORCID,Michal Ciebiera 5ORCID,Basar Cander 6,Mansur Rahnama-Hezavah 7 and Łukasz Szarpak 8,9,10 ORCID
1 Research Unit, Polish Society of Disaster Medicine, 05-806 Warsaw, Poland
2 Department of Obstetrics, University Hospital Zurich, Frauenklinikstrasse 10, 8091 Zurich, Switzerland
3 Department of Gynecology, University Hospital Zurich, Frauenklinikstrasse 10, 8091 Zurich, Switzerland
4 Research Unit, International Academy of Ecology and Medicine, 02091 Kyiv, Ukraine
5 Second Department of Obstetrics and Gynecology, Centre of Postgraduate Medical Education, 00-189 Warsaw, Poland
6 Department of Emergency Medicine, Bezmialem Vakif University, Fatih, 34093 Istanbul, Turkey
7 Chair and Department of Oral Surgery, Medical University of Lublin, 20-093 Lublin, Poland
8 Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX 77030, USA
9 Research Unit, Maria Sklodowska-Curie Bialystok Oncology Center, 15-027 Bialystok, Poland
10 Institute of Outcomes Research, Maria Sklodowska-Curie Medical Academy, 00-136 Warsaw, Poland

Vitamin D can modulate immune responses, and its deficiency is linked to increased autoimmunity and susceptibility to infection. In the general population, it has been observed that serum vitamin D levels are connected with the risk of COVID-19 and its severity. Our study aims to examine reported findings on the effect of vitamin D serum levels on infection of COVID-19 during pregnancy. PubMed, Web of Science, Embase, and Cochrane Library were searched for relevant studies. Serum vitamin D serum levels in COVID-19-positive and COVID-19-negative pregnant women were 24.61 ± 20.86 ng/mL and 24.12 ± 17.33 ng/mL, respectively.
In mild vs. moderate to critical COVID-19 pregnant women, vitamin D serum levels were 16.71 ± 9.04 ng/mL vs. 10.7 ± 9.37 ng/mL and severe vs. non-severe were 13.21 ± 11.47 ng/mL vs. 15.76 ± 10.0 ng/mL. Only one study reported vitamin D serum levels in the placenta of COVID-19-positive pregnant women compared with the control and results varied and amounted to 14.06 ± 0.51 ng/mL vs. 12.45 ± 0.58 ng/mL, respectively.
Vitamin D deficiency tends to be common in pregnant women who have COVID-19, and the level of this vitamin has been demonstrated to have a strong correlation with the severity of the illness. As vitamin D serum levels correlate with COVID-19 symptoms and even with its occurrence, appropriate vitamin D supplementation in the prenatal period is suggested.
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VitaminDWiki - Pregnancy category contains

864 items in Pregnancy category

 - see also

VitaminDWiki -Healthy pregnancies need lots of vitamin D contains

0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

17+ VitaminDWiki Pregnancy pages with "COVID" in title

This list is automatically updated

Items found: 17
Title Modified
Yet another reason to take Vitamin D while pregnant – fight COVID - meta-analysis May 2023 10 Jun, 2023
COVID lockdowns reduced Vitamin D levels - should supplement - April 2023 02 May, 2023
Pfizer COVID vaccination during pregnancy clinical trial is still not published - Feb 2023 25 Feb, 2023
Worse COVID during 3Q pregnancy if 2.5 ng lower Vitamin D – meta-analysis Sept 2022 14 Sep, 2022
2.3 X more poor Neurodevelopment in infant if COVID late in pregnancy – June 2022 11 Jun, 2022
Severe COVID while pregnant - none had taken any vitamin D – Oct 2021 01 May, 2022
COVID while pregnant: 2.6 X more likely to be Vitamin D deficient (need to supplement) - March 2022 12 Apr, 2022
COVID breakthru 2X more likely if pregnant (should take Vitamin D) - April 2022 02 Apr, 2022
COVID 2.6 X more likely if low Vitamin D (during pregnancy in this case) – March 2022 26 Mar, 2022
COVID-19 more severe if low Vitamin D (1.8X for pregnancy) – Nov 2021 24 Nov, 2021
Far less vitamin D in breast milk if COVID-19 (no surprise) – Aug 2021 14 Aug, 2021
COVID-21 (COVID-19 with mutations) causing increased pregnancy problems in Brazil and India – May 2021 27 May, 2021
COVID-19, dark skin, pregnancy - Dr. Grimes, etc. - May 2021 27 May, 2021
Increased pregnancy problems with COVID-19 – meta-analysis and letter to editor – April 2021 18 May, 2021
COVID-19 while pregnant increased many infant health problems by 1.5X – April 29, 2021 29 Apr, 2021
COVID-19 while pregnant is not good (increased risk of dying by 22X) – April 2021 26 Apr, 2021
Vitamin D plus Inositol might help pregnancies during COVID-19 – April 2021 26 Jan, 2021

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