Table of contents
- Cholesterol Paradigm Shift in Japan April 2015 - 100 pages
- Death rate and diseases all DECREASE as Cholesterol is increased in 167 countries
- Update Dec 2015 - a reader extracted the data from the spreadsheet
- Suppressed study had found that lowering Cholesterol ==> increased chance of death
- Vitamin D is Synthesized From Cholesterol and Found in Cholesterol-Rich Foods Masterjohn 2006
- Less cholesterol in diet resulted in less vitamin D in blood (in mice) – Feb 2016
- The Relation of Cholesterol to Vitamin D - 1927
- Clinical trial to explore link between vitamin D and cholesterol Jan 2010
- $10.6 billion spent in 2009 in the US on cholesterol lowering foods
- Vitamin D and Cholesterol book by Dr, Grimes reviewed at VitaminDWiki
- Quote on Cholesterol and vitamin D from Vitamin D Council
- There is a lot of concern that decreasing cholesterol is the WRONG thing to do
- High cholesterol is Good
- Decrease in Cholesterol during the last 30 years CDC
- What Is the Connection Between Vitamin D and Cholesterol? WiseGeek
- Very low LDL increases risk of stroke by 2X - April 2019
- See also at VitaminDWiki
- See also on web
Towards a Paradigm Shift in Cholesterol Treatment. A Re-examination of the Cholesterol Issue in Japan
Ann Nutr Metab 2015;66(suppl 4):1-116 (DOI:10.1159/000381654)
Hundreds of charts - here are just two
- Chapter 1 Cholesterol and Mortality
- Chapter 2 Cholesterol and Disease
- Chapter 3 Familial Hypercholesterolemia: The Key to Solving the Cholesterol Myth
- Chapter 4 Japan Atherosclerosis Society (JAS) Guidelines
- Chapter 5 The Latest Edition of the 2012 JAS Guidelines Part I: The Most Important Figure and Table
- Chapter 8 The Latest Edition of the JAS Guidelines (2012) Part IV: The Adverse Effects of Statins
- Chapter 9 Are Statins Effective for Preventing Coronary Heart Disease in Type 2 Diabetes Mellitus in Japan, as the 2012 JAS Guidelines Recommend?
- Chapter 10 Hypertriglyceridemia and Low Levels of High Density Lipoprotein Cholesterol: Are They Treatment Targets?
in 167 countries Death rate, infectious diseases - - - non-communicable , cardio - -
All decrease as Cholesterol is increased
Detailed files are attached at the bottom of this page
and got the resulting simple Mortality vs cholesterol level chart
Suppressed study had found that lowering Cholesterol ==> increased chance of death
- "The study,18 conducted from 1968 to 1973, included 9,423 participants between the ages of 20 and 97, making it the largest trial of its kind."
- "For every 30 point drop in total cholesterol there was a 22 percent increased chance of death."
- Statins continue to be prescribed (to lower cholesterol) even though:
"100 people need to take a statin as a primary preventive for five years in order for one or two people to avoid a heart attack, and none will actually live longer"
- Sources of Vitamin D: Sunlight
- Sources of Vitamin D: Cholesterol-Rich Foods
- Are Plants and Irradiated Mushrooms a Source of Vitamin D?
- The Many Functions of Vitamin D: More Than Just Calcium
- Do Cholesterol-Lowering Statins Inhibit Vitamin D Synthesis?
- Requirements: How Much Vitamin D Do We Need?
- Toxicity: How Much is Too Much?
- Make Sure to Get Your Vitamin A
- Without Cholesterol, There Is No Vitamin D
Newer article by same author
From Seafood to Sunshine: A New Understanding of Vitamin D Safety Dec 2006
Vitamin D and Cholesterol book by Dr, Grimes reviewed at VitaminDWiki
- What is the purpose of cholesterol? 2015 overview by Dr. Grimes
Our most important hormones depend upon adequate reserves of cholesterol for their production and nowhere is this more important than as the precursor substance for the synthesis of Vitamin D, known also as calcitriol. Researchers in this field are sufficiently concerned from the results of their studies to pronounce that we are in the midst of an epidemic of vitamin D deficiency of immense proportion ~ Duane Graveline MD MPH, former NASA Astronaut, former USAF flight surgeon, and retired family doctor.'
A huge number of places on the web describe the problem, such as Cholesterol Skeptics
Study from Israel of heart failure patients Dr. Grimes 2018
Vitamin D and cholesterol are closely linked, both in bodily processes as well as in nutrition. One important role of cholesterol is that is plays a vital part in the synthesis of vitamin D in the body. In the diet, vitamin D is found in foods that have high levels of cholesterol, such as cod liver oil and eggs. Studies have been done to see if there is a correlation between the levels of vitamin D a person has and their cholesterol levels, but results are inconclusive.
There is a close connection in the body between Vitamin D and cholesterol. One of the biggest sources of vitamin D for individuals is contact with sunlight; upon exposure to sunlight the body can synthesize its own vitamin D. Cholesterol is involved in the process of synthesizing vitamin D from sunlight, and without cholesterol, vitamin D synthesis would be impossible.
Dietary sources also provide a connection between Vitamin D and cholesterol. There is typically a correlation between foods that are rich in vitamin D and cholesterol — that being, foods that are high in vitamin D are often also high in cholesterol. For example, cod liver oil is an excellent source of vitamin D, but it is also very high in cholesterol. Other foods that are high in vitamin D are lard and eggs, two foods that are notorious for being high in cholesterol.
Many scientists are researching a possible correlation between an individual’s levels of vitamin D and cholesterol. High cholesterol, also known as hypercholesterolemia, effects many individuals and increases o!ne’s risk for heart disease and stroke. It is important to keep cholesterol levels under control in order to stay healthy, which is why many are searching to see if there is a correlation between these two nutrients.
Studies seem to show that individuals with higher levels of vitamin D have lower cholesterol levels and are generally healthier overall than individuals with low levels of vitamin D. Yet, these studies do not show a direct correlation between the two. For example, vitamin D is involved in calcium absorption, so having higher levels of vitamin D may mean that more calcium is being absorbed and that calcium is the nutrient actually causing an effect on cholesterol. Individuals with high levels of vitamin D also may have these high levels because they spend a lot of time outdoors in the sunlight doing physical activities, which is one way to reduce cholesterol. Although studies indicate that individuals with high levels of vitamin D have lower cholesterol, it is unknown whether or not this result is directly related to vitamin D.
There are many benefits of vitamin D, such as helping to regulate levels of calcium, preventing osteoporosis, and improving moods. If one chooses to take vitamin D supplements to help lower cholesterol or to gain any of the many benefits of this nutrient, they should choose their supplements carefully. Two popular types of vitamin D are vitamin D2 and vitamin D3. Vitamin D3 is naturally occurring and easy for the body to process. Vitamin D2 is difficult for the body to process and may result in toxicity. Vitamin D3 is the safer supplement to choose, and daily recommended dosages should always be followed.
Written by B. Koch, Edited by Jenn Webb, Last Modified: 04 December 2010
- Very Low Cholesterol May Increase Stroke Risk New York Times
- More cholesterol is associated with more vitamin D – June 2013
- Vitamin D increases HDL several items
- Statins and vitamin D
- Vitamin D bioavailability is associated with cholesterol – Jan 2011
- Eating less cholesterol is harmless other than it causes of vitamin D deficiency – June 2011
- "The great cholesterol myth; unfortunate consequences of Brown and Goldstein's mistake."
- Cholesterol is needed to produce both Vitamin D and Cortisol
- Hypothesis: High Cortisol reduces Cholesterol available to produce vitamin D
- Overview Obesity and Vitamin D
- Short treatment with vitamin D did not reduce cholesterol – Sept 2012
8 weeks for those with high BMI did not reduce cholesterol levels
- from Dr. Oz on VitaminDWiki Cholesterol goes up in the winter to increase the amount to convert to vitamin D
- !Vitamin D production was dependent on cholesterol and not skin color – Feb 2010
- Cholesterol scam: Disinformation slowly unraveling among health professionals Natural News Feb 2012
- Heart Disease and Cholesterol Myth Health Skeptic approx 2010 - extensive set of blog posts, lots of links, videos, books,
- Cholesterol and Longevity Mar 2011
- Each 10-mg/dl increment in HDL cholesterol was associated with a 14% (decrease) in risk of mortality before 85 years of age.
- Cholesterol: It’s All Good Green Med Info Sept 2012
Those with highest LDL gained the most muscle mass
Without cholesterol, he points out, we would die. In fact, studies in the elderly have shown that those with the lowest levels of cholesterol are at highest risk of death from all causes.
- Natural Niacin Beats Prescription Zetia for Cholesterol Green Med Info Oct 2012
Vitamin B3 was doing so much better than Zetia that a clinical trial was stopped
$2 billion of Zetia was sold in 2010 to be used with Statins to reduce cholesterol
Nothing about vitamin D - but interesting anyway
- Many reasons why vitamin D deficiency has become epidemic
- How LOW Cholesterol Can Harm Your Health Green Medical Information, Sept 2012
Cholesterol Is Needed To Prevent Aggression:
Cholesterol Is Needed To Fight Cancer:
Cholesterol Is Needed To Prevent Hemorrhagic Stroke:
Cholesterol Is Needed for Memory:.
Cholesterol Helps Us Fight Infection:
- New Drugs for Lipids Set Off Race New York Times Nov 2012
PCSK9 inhibitors can be used in addition to Statins - not expected until 2015
No studies so far of > 100 people nor >12 weeks.
No indication that the new drugs will actually improve life span
New drug has to be injected every 2-4 weeks
- TedEx Video The Big Fat Surprise March 2014
Also: Amazon full Kindle book $12,Insta-read (30 minute) summary by the author $3
- Rise of saturated fat in diet does not raise fats in blood MedNewsToday Nov 2014
Reporting on a recent PLOS ONE study by Jeff Volek
- Systematic Review Finds No Grounds for Current Warnings Against Saturated Fat Mercola Dec 2014
meta-analysis of 49 observational studies and 27 randomized controlled trials
FDA to remove partially hydrogenated oils from the list of "generally recognized as safe"
No change of policy anticipated by American Heart Association
- Evidence to Support Dietary Fat RecommendationsMeta-Analysis Finds Medscape Feb 2015
Not a single RCT has supported the 1977 US recomensation to reduce saturated fats
The recommendation had some bad results:
reducing Vitamin D from the sun (which needs cholesterol),
increasing the use of Omega-6
increasing the use of refinded carohydrates
- Cost-effectiveness of 10-Year Risk Thresholds for Initiation of Statin Therapy for Primary Prevention of Cardiovascular Disease JAMA July 2015
Their simulation "assumes" that cholesterol is bad and that statins are needed and have no side effects
Seems like they have missed cholesterol news of the past 5-10 years
- Bidirectional associations between circulating vitamin D and cholesterol levels: The Rotterdam Study
Two way Interaction between HDL-C and vitamin D Aug 2015.
Increasing Total Cholesterol decreases vitamin D, but not the other way around.
- Cholesterol, Statins, and the Council of Nicaea Oct 2016 Dr. David Grimes
Increased cholesterol increased death rate for ages 30-39
But, did NOT increase death rate for ages 56-65
Scotland Study of pravastatin in 1980's (at peak of CHD epidemic
In the 1980's the “number needed to be treated” (NNT) = 50
Now NNT = about 500
Cost of pravastatin to treat 500 men = £ 60,000 (assuming age of 60 years).
Note: Vitamin D has much lower NNT than statins
Multiple Sclerosis NNNT = 1.3
Asthma NNNT = 27
Premature birth = 10