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Poor sleep 1.5 X more likely if less than 20 ng of Vitamin D – meta-analysis Oct 2018

The Association between Vitamin D Deficiency and Sleep Disorders: A Systematic Review and Meta-Analysis

Nutrients 2018, 10(10), 1395; https://doi.org/10.3390/nu10101395 (registering DOI)
Qi Gao 1, Tingyan Kou 1, Bin Zhuang 2, Yangyang Ren 1, Xue Dong 1 and Qiuzhen Wang 1,*qdwangqiuzhen@126.com
1 Department of the College of Public Health, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China
2 Department of the medical college of Qingdao University, Qingdao 266021, China


Sleep category starts with

55 items in sleep category

Sleep Apnea 253 items as of Oct 2018
Search VitaminDWiki for (sleep OR insomnia) Magnesium 228 items as of June 2019

See also Sleep problems cured by vitamin D, etc. – workshops and patient workbooks – Gominak 2018

Sleep is aided by Vitamin D + Vitamin Bs

Items in both categories Sleep and Omega-3 are listed here:

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Epidemiology studies have investigated the association between vitamin D and the risk of sleep disorders, but the results remain controversial. Therefore, we conducted this meta-analysis with the goal of clarifying the association between vitamin D and sleep disorders risk. All relevant studies were searched using PubMed, EMBASE, and Web of Science from inception to January 2018. Pooled odds ratios (ORs) and 95% confidence interval (CIs) were calculated using a fixed-effect model A total of nine studies (6 cross-sectional, 2 case-control, and 1 cohort studies) involving 9397 participants were included.
By comparing the lowest verse highest levels of serum vitamin D, we found that participants with vitamin D deficiency (VDD) had a significantly increased risk of s

  • sleep disorders (OR: 1.50, 95% CI: 1.31, 1.72).

Subgroup analysis showed that VDD also was associated with

  • poor sleep quality (OR: 1.59, 95% CI: 1.23, 2.05),
  • short sleep duration (OR: 1.74, 95% CI: 1.30, 2.32), and
  • sleepiness (OR: 1.36, 95% CI: 1.12, 1.65).

Subgroup analyses further indicated that serum 25(OH)D <20 ng/mL could significantly increase the risk of unhealthy sleep.
This meta-analysis suggest that vitamin D deficiency is associated with a higher risk of sleep disorders. More high-quality cohort studies and randomized controlled trials (RCTs) are needed to verify this association.

Created by admin. Last Modification: Saturday June 22, 2019 16:02:33 GMT-0000 by admin. (Version 8)

Attached files

ID Name Comment Uploaded Size Downloads
10634 Sleep meta-min.pdf PDF 2018 admin 01 Oct, 2018 14:42 408.88 Kb 19
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