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Toggle Health Problems and D

Acne

Did you know?
  • Vitamin D was voted best acne treatment Feb 2011 http://www.acne.org
  • Topical Vitamin D appears help acne (oil, cream, or paste made from capsules)
  • Putting vitamin D on an affected area for a few days often clears up acne
  • An acne clinical trial with Vitamin D intervention is underway   (More acne info below)

Learn how Vitamin D is essential for good health
  Watch a 5 minute video "Does Less Sun Mean more Disease?"
  Browse for other Health Problems and D in left column or here
  see also Supplementing and More in the menu at the top of every page
If you have a disease associated with low Vit D take Vit D
Raising your Vit D levels will substantially prevent other low-Vit D health problems
Often your specific health problem will also be treated

Vitamin D is very good for the skin, acne

Items in both categories Skin and Inflamation are listed here:


Web also shows popularity of vitamin D for the skin, acne


Acne associatd with 7 ng lower level of vitamin D - Meta-analysis March 2021

J Cosmet Dermatol . 2021 Mar 10. doi: 10.1111/jocd publisher wants $8 for the PDF
Vitamin D deficiency and effect of vitamin D supplement to acne patients: A systematic review and meta-analysis
Meng Wang 1, Yuan Zhou 1, Yan Yan 1

Acne vulgaris, a chronic inflammatory dermatosis, affects approximately 85% of adolescents and young adults. The level of vitamin D in acne patients and the effect on acne patients of a vitamin D supplementation have previously been documented; however, it remains to be disputed whether vitamin D deficiency is normal in acne patients. This paper explores the relationship between vitamin D and acne levels and the advantageous implications of vitamin D supplements on acne. From every database start date until December 2020, we checked the PubMed, EMBASE, MEDLINE and the Cochrane libraries. Case-controls or randomized controlled trial reporting on the serum 25(OH)D level and the efficacy of vitamin D supplement to acne patients were included. The serum 25(OH)D levels in acne patients is lower (standardized mean difference = -7.66ng/ml; 95% confidence interval (CI) = -10.92 to -4.40). Articles also revealed the prospect of a therapeutic breakthrough through the supplementing of vitamin D for acne patients. Our research offers a new guide in the field of acne prevention and health care.


  • Way back in 1938 Acne was nicely treated by 8,000 to 14,000 IU daily
  • 2016 Randomized Clinical Trial found that after 8 weeks of treatment, inflammatory lesions in the
    • vitamin D group decreased by 34.6% compared to
      • only 5.8% in the control group.

Woman tried to stop oily skin for decades - 4,000 IU of vitamin D did it - 2018

Acne.org Forum March 2018
"I've tried EVERYTHING including accutane (4 rounds, antibiotics (3 years), spironolactone (3 years), topical tretinoin (10 years, still using), useless lotions and potions.. you name it, i've tried it."


Study found no improvement in chronic eczema with 2,000 IU of vitamin D for 3 months

Serum Vitamin D levels and Vitamin D supplementation do not correlate with the severity of chronic eczema in children March 2015
Results"Vitamin D concentrations in patients with moderate and severe eczema were not statistically different from Vitamin D concentration detected in the serum of patients with mild eczema. Furthermore, we did not find any correlation between Vitamin D levels, total IgEs and SCORAD index, both in the Sensitized and in the Not-Sensitized group. The Vitamin D3 supplementation did not influence the SCORAD severity or the total IgEs concentration."

VitaminDWiki wonders why. Perhaps because they did not use topical vitamin D?


Vitamin D levels do not matter with Eczema until about age 4 - Dec 2015

Associations of maternal and fetal 25-hydroxyvitamin D levels with childhood eczema. The Generation R Study.
Pediatr Allergy Immunol. 2015 Dec 19. doi: 10.1111/pai.12530. [Epub ahead of print]
Gazibara T1,2,3,4, Elbert NJ1,5, den Dekker HT1,2,3, de Jongste JC2, Reiss I6, McGrath JJ7,8, Eyles DW7,8, Burne TH7,8, Tiemeier H3,9,10, Jaddoe VW1,3,11, Pasmans SG5, Duijts L2,3,6.

BACKGROUND:
Exposure to low levels of vitamin D in fetal life might affect the developing immune system, and subsequently the risk of childhood eczema. We examined whether 25-hydroxyvitamin D levels in mid-gestation and at birth were associated with the risk of eczema until the age of 4 years.
METHODS:
In a population-based prospective cohort study of 3,019 mothers and their children, maternal blood samples in mid-gestation and umbilical cord blood samples at birth were used to determine 25-hydroxyvitamin D levels (severely deficient <25.0 nmol/L, deficient 25.0-49.9 nmol/L, sufficient 50.0-74.9 nmol/L, optimal ≥75.0 nmol/L). Eczema was prospectively assessed by annual questionnaires until the age of 4 years. Eczema patterns included never, early (age ≤1 year only), late (age >1 year only), and persistent eczema (age ≤ and >1 year). Data were assessed using generalized estimating equations and multinomial regression models.
RESULTS:
Compared with the optimal 25-hydroxyvitamin D group, sufficient, deficient and severely deficient groups of 25-hydroxyvitamin D level in mid-gestation were not associated with the risk of overall eczema (odds ratios (95%confidence interval): 1.09 (0.82, 1.43), 1.04 (0.87, 1.25) and 0.94 (0.81, 1.10), p-values for trend >0.05), nor with eczema per year or eczema patterns in children up to the age of 4 years. Similarly, we observed no associations of 25-hydroxyvitamin D groups at birth with any eczema outcome.
CONCLUSION:
Our results suggest that levels of 25-hydroxyvitamin D in mid-gestation and at birth are not associated with the risk of overall eczema, eczema per year or eczema patterns among children until the age of 4 years


Atopic dermatitis reduced a bit by 1600 IU of vitamin D - RCT Nov 2020 - FREE PDF

The impact of vitamin D supplementation as an adjuvant therapy on clinical outcomes in patients with severe atopic dermatitis: A randomized controlled trial.
Pharmacology Research & Perspectives, 30 Nov 2020, 8(6):e00679, DOI: 10.1002/prp2.679
Mansour NO1, Mohamed AA2, Hussein M3, Eldemiry E4, Daifalla A5, Hassanin S6, Nassar N7, Ghaith D8, Mohamed Salah E9
Treatment group (with only 1600 IU) got to only 36 ng
Image
 Download the PDF from VitaminDWiki

Vitamin D supplementation with standard treatment yielded positive clinical outcomes in mild and moderate atopic dermatitis; however, the potential benefit of vitamin D in severe cases remains unclear. This study aimed to evaluate the impact of vitamin D supplementation on response to standard treatment in pediatrics with severe atopic dermatitis. The patients were randomized to receive either vitamin D 3 1600 IU/day or placebo, plus baseline therapy of topical 1% hydrocortisone cream twice daily for 12 weeks. The primary endpoints were the change in mean Eczema Area and Severity Index (EASI) score at the end of the study and the mean percent change in EASI score from baseline to week 12. Eighty-six subjects completed the study. The treated group achieved a significant higher level of 25 hydroxy vitamin D (P < .001) compared to control group at week 12. The mean EASI score was significantly lower in the treatment group compared to placebo group (P = .035). The percent change in EASI score from baseline differed significantly between the supplementation (56.44 ± 29.33) and placebo (42.09 ± 19.22) groups after intervention (P = .039). Vitamin D supplementation could be an effective adjuvant treatment that improves the clinical outcomes in severe atopic dermatitis.


Eczema: A Systematic Review and Meta-Analysis - Oct 2019

Assessment of the Effectiveness of Vitamin Supplement in Treating Eczema: A Systematic Review and Meta-Analysis
 Download the PDF from VitaminDWiki 5 Vitamin D Studies


Differences between acne and dermatitis

How to Tell the Difference between Acne and Dermatitis Feb 2017

  • Acne is the result of dead skin and excess oil clogging pores.
  • Dermatitis is an inflammation of the skin caused by contact with allergens, irritants, or other triggers.

Difference Between Rosacea, Acne and Eczema Aug 2017
How to Tell the Difference Between Acne and Dermatitis 2017 ?

Attached files

ID Name Comment Uploaded Size Downloads
15225 Oct 2019.pdf PDF 2019 admin 11 Mar, 2021 12:31 1.12 Mb 68
15224 Atopic RCT 2020.jpg admin 11 Mar, 2021 12:19 27.31 Kb 703
15223 Atopic RCT 2020.pdf PDF 2020 admin 11 Mar, 2021 12:19 1.28 Mb 85
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