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Zinc and Vitamin D

It appears that
  • Low Zinc results in poor Vitamin D Receptor function
  • Colds can be stopped by taking Zinc every 2-3 hours
  • Zinc improves the immune system and influences 300 enzymes
  • Zinc deficiency has increased due to lack of Zinc in fertilizers and Roundup problems
  • Zinc taste tests kindof sortof work
  • No agreement as to the best Zinc supplement
  • Not much zinc is needed - 10 mg seems OK for most people,
       20 mg has been proven to cut in half the progression of prediabetes to diabetes
  • Founder of VitaminDWiki buys zinc bulk supplements from Amazon
  • Added to my morning cereal (prepared 2 weeks at a time) 10mg of daily Zinc costs much less that 1 cent/day

Learn how Vitamin D is essential for good health
  Watch a 5 minute video "Does Less Sun Mean more Disease?"
  Browse for other Health Problems and D in left column or here
  see also Supplementing and More in the menu at the top of very page
If you have a disease associated with low Vit D take Vit D
Raising your Vit D levels will substantially prevent other low-Vit D health problems
Often your specific health problem will also be treated

Some hints that Zinc is important

See also Zinc in VitaminDWiki

See also web

  • Zinc Top Ten Home Remedies 2017

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  • Zinc Is Crucial for Heart Health Mercola Jan 2016
    "Zinc May Help Regulate Your Heartbeat"
    "Your Body Contains More Than 300 Zinc-Dependent Enzymes"
    "How Much Zinc Do You Need?" RDA is 11 mg/day (men) 8 mg/day (women)
    Deficient due to lack of Zinc in fertilizers, glyphosate which binds to Zinc
    ACE inhibitors and thiazide diuretics consume Zinc
  • Zinc decreases potency of some antibiotics if taken concurrently
    • No problem with potency if take antibiotics 2 hour before or 4 hours after the Zinc
  • Zinc Mercola Feb 2018 -"While zinc and selenium deficiencies can occur at any age, by the time you reach 60, your risk can soar as high as 40 percent."
    signs of zinc deficiency:If food doesn't taste or smell as good as it used to, Brain fog and decreased alertness. Frequent respiratory illnesses. Difficulty sleeping. Slow wound healing, Lack of appetite, Leaky gut and gastrointestinal complaints, Occasional moodiness and feeling blue. Impaired hearing, Reduced libido, Occasional loose stools, Increased food and environmental allergies, Hair loss, rashes and other skin issues
    "The fact that these signs mimic other conditions is one of the reasons many people never suspect a zinc deficiency. None of these stand out as a “zinc” red flag all by itself!"
  • Mercola Dec 2018
    "Second after iron, zinc is the most common mineral found in your body"
    "Also, if you’re dealing with any type of chronic illness, ask your health practitioner about zinc."
    "Emotional stress is one of the biggest factors behind zinc deficiency."
  • Modern Day Zinc Deficiency Epidemic March 2013
    lots of great information - but they do not permit copy/paste
  • Linus Pauling Institute
    Lots of information, such as "zinc deficiency has been estimated to cause more than 450,000 deaths in children under the age of 5 annually"
  • Vitamin D and other vitamins and minerals VitaminD Council
    Nice section on ZINC
  • Zinc Deficiency taste test
  • Quackery or Solid Science: The Zinc Tally Test - Does it Work? How Does It Work? And How Reliable is It? Suppversity Jan 2014
    Many reviews conclude the Zinc taste test does not work (but low Zinc does make for poorer taste)
  • https://examine.com/supplements/zinc/ excellent with lots of links to clinical research
    "Superloading zinc by taking up to 100mg zinc a day is confirmed to be safe in the short term (2-4 months), but because this dose is higher than the 40mg Tolerable Upper Limit (TUL) of zinc, prolonged superloading is not advised. Zinc’s intestinal uptake is hindered by other minerals, including Calcium, Magnesium, and Iron, since they all use the same transporter. If the transporter’s uptake limit (800mg) is exceeding between these four minerals, absorption rates will fall. Taking less than 800mg of these four minerals at the same time is fine."
  • ConsumerLabs on Zinc updated Oct 2017
    No consistant differerences in bio-availability of the different Zinc compounds
    They have excellent supplementation information on virtually all supplements $42/year - but has a 5 day free trial
  • Behavioral impairments in animal models for zinc deficiency - Jan 2015
     Download the PDF from VitaminDWiki
    has the following pentagon

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+  Download the Jan 2015 PDF from VitaminDWiki

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  • Estimating the Global Prevalence of Zinc Deficiency PLOS ONE Nov 2012
    Image
     Download the PDF from VitaminDWiki
  • Zinc Deficiency chapter WHO, date unknown
     Download the PDF from VitaminDWiki
  • Zinc Deficiency Wikipedia
    "Central Anatolia, in Turkey, was a region with zinc-deficient soils and widespread zinc deficiency in humans. In 1993, a research project found that yields could be increased by 6 to 8-fold and child nutrition dramatically increased through zinc fertilization."
  • http://www.zinc.org/crops/
    "A study for the Food and Agricultural Organization (FAO) by Sillanpää found that zinc was the most commonly deficient micronutrient in the world. The study, which examined 190 field trials in fifteen countries, found that zinc deficiency occurred in one out of every two trials."
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Note: Taking Zinc acetate every 2 hours with vitamin C stops most colds


Do You Have A Copper and Zinc Imbalance?

Nice article has the following charts and many references
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Zinc and the immune system - 2000

Proc Nutr Soc. 2000 Nov;59(4):541-52.
Rink L1, Gabriel P.
1Institute of Immunology and Transfusion Medicine, University of Lübeck School of Medicine, Ratzeburger Allee 160, D-23538 Lübeck, Germany. rink at immu.mu-luebeck.de

Zn is an essential trace element for all organisms. In human subjects body growth and development is strictly dependent on Zn. The nervous, reproductive and immune systems are particularly influenced by Zn deficiency, as well as by increased levels of Zn. The relationship between Zn and the immune system is complex, since there are four different types of influence associated with Zn.

  • (1) The dietary intake and the resorption of Zn depends on the composition of the diet and also on age and disease status.
  • (2) Zn is a cofactor in more than 300 enzymes influencing various organ functions having a secondary effect on the immune system.
  • (3) Direct effects of Zn on the production, maturation and function of leucocytes.
  • (4) Zn influences the function of immunostimulants used in the experimental systems.

Here we summarize all four types of influence on the immune function. Nutritional aspects of Zn, the physiology of Zn, the influence of Zn on enzymes and cellular functions, direct effects of Zn on leucocytes at the cellular and molecular level, Zn-altered function of immunostimulants and the therapeutic use of Zn will be discussed in detail.
PMID: 11115789
 Download the PDF from VitaminDWiki


Zinc National Institute of Health (US)

https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/
has the following Zinc AI and RDA

AgeMaleFemalePregnancyLactation
0–6 months2 mg*2 mg*
7–12 months3 mg3 mg
1–3 years3 mg3 mg
4–8 years5 mg5 mg
9–13 years8 mg8 mg
14–18 years11 mg9 mg12 mg13 mg
19+ years11 mg8 mg11 mg12 mg

* Adequate Intake (AI)
 Download the NIH PDF from VitaminDWiki

  • "In a randomized, double-blind, placebo-controlled clinical trial, 50 subjects (within 24 hours of developing the common cold) took a zinc acetate lozenge (13.3 mg zinc) or placebo every 2–3 wakeful hours. Compared with placebo, the zinc lozenges significantly reduced the duration of cold symptoms (cough, nasal discharge, and muscle aches) [67]."

Zinc half life in the body - a day or 4 months?


8 major uses of Zinc in the body

Science Daily reporting on a 2014 study

  • Brain: The blood zinc level is less in patients with Alzheimer's and Parkinson's disease (Brewer, and others 2010).In a rodent study, it was observed that zinc behaves like an antidepressant (Nowak and others, 2005).
  • Cardiovascular System: Zinc performs a noteworthy role in the regulation of arterial blood pressure. Males and females were reported to metabolize zinc differently when suffering from hypertension (Tubek, 2007).
  • Liver: Zinc deficiency in the liver occurs not only in those with liver cirrhosis, but also in less advanced alcoholic and nonalcoholic liver disease (Bode and others, 1998).
  • Pregnancy: A mild deficiency of zinc during a pregnancy can cause increased maternal morbidity, abnormal taste sensation, prolonged gestation, inefficient labor, atonic bleeding, and an increased risk to fetuses (Jameson, 1993).
  • Diabetes: Zinc is very important in the synthesis, storage, and secretion of insulin (Chausmer 1998). A low level of zinc has been shown to play a role in diabetics with associated disease conditions such as coronary artery disease and several related risk factors including hypertension, and elevated levels of triglycerides (Singh and others, 1998).
  • Endocrine System: Studies show a correlation between zinc deficiency in geriatric patients and reduced activity of the thymus gland and thymic hormones, decreased response to vaccinations, and reduced immunity (Haase and Rink, 2009).
  • Healing: Zinc deficiency has been linked with delayed wound healing, and has been found to be crucial to the healing of gastric ulcers especially at the early stage (Kennan and Morris, 1993; Andrews and Gallagher-Allred, 1999; Watanabe, 1995).
  • Pneumonia: Zinc may shorten the duration of severe pneumonia and time in the hospital (Brooks, 2004).

Animal doctors know more about Zinc than human doctors (similar to Vitamin D knowledge)

Behavioral impairments in animal models for zinc deficiency - Jan 2015
 Download the PDF from VitaminDWiki
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Frequent Zinc shortens colds by 30% - meta-analysis 2017

Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage
 Download the PDF from VitaminDWiki


World Health Organization - Zinc

WHO as of 2018

  • "Using food availability data, it is estimated that zinc deficiency affects about one-third of the world's population, with estimates ranging from 4% to 73% across subregions"
  • "Worldwide, zinc deficiency is responsible for approximately 16% of lower respiratory tract infections, 18% of malaria and 10% of diarrhoeal disease"
  • "Attributable DALYs were higher, with zinc deficiency accounting for about 2.9% of worldwide loss of healthy life years"

Zinc and Vitamin D        

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10828 Zinc humans.jpg admin 11 Nov, 2018 15:53 22.36 Kb 288
10827 Zinc animals.jpg admin 11 Nov, 2018 15:52 33.85 Kb 276
10826 Behavioral impairments in animal models for zinc deficiency.pdf admin 11 Nov, 2018 15:52 1.77 Mb 6
10823 Zinc shortens lenght of colds by 30 percent.pdf admin 11 Nov, 2018 09:41 383.18 Kb 7
10670 Zinc Deficiencies.jpg admin 12 Oct, 2018 15:56 48.71 Kb 573
9469 Zinc top 10.jpg admin 08 Mar, 2018 22:45 61.94 Kb 2855
6724 Zinc and immune system.pdf PDF admin 02 Jun, 2016 14:51 266.81 Kb 1116
6723 Zinc excess and deficiency.jpg admin 02 Jun, 2016 14:37 54.66 Kb 8022
6722 Zinc immune.jpg admin 02 Jun, 2016 14:37 61.67 Kb 7128
6425 Zinc crops.jpg admin 25 Feb, 2016 21:52 13.00 Kb 7105
6424 WHO Zinc Deficiency.pdf admin 25 Feb, 2016 18:45 96.91 Kb 1426
6423 Low Zinc, stunting.jpg admin 25 Feb, 2016 18:36 38.76 Kb 7379
6422 Estimating the Global Prevalence of Zinc Deficiency - Nov 2012.PDF admin 25 Feb, 2016 18:36 915.20 Kb 1270
6421 Zinc pentagon.jpg admin 25 Feb, 2016 17:22 75.28 Kb 7604
6420 Zin Deficiency Jan 2015.pdf PDF 2015 admin 25 Feb, 2016 17:21 1.77 Mb 1444
6419 Zinc deficiency test.jpg admin 25 Feb, 2016 17:14 23.45 Kb 1870
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