- Better total hip replacement if have high vitamin D
- More pain after knee surgery if low vitamin D – Oct 2015
- Hip fracture outcome 5X more likely to be poor if low vitamin D – Jan 2015
- Knee Arthroplasty complications were 2 X more likely if low vitamin D -May 2018
- Guideline following hip fracture – 50000 IU vitamin D daily for 7 days – Jan 2013
- Vitamin D and fractures – 24 meta-analyses and counting – Dec 2014
- Fewer Complications Following Revision Hip and Knee Arthroplasty in Patients with Normal Vitamin D Levels – March 2017
The items which are in both Intervention and Trauma/Surgery are listed here
- Half as much AFIB after bypass if 600,000 IU of vitamin D before surgery – RCT April 2022
- Half as many problems if take Vitamin D (300,000 IU) before thyroidectomy – RCT Jan 2021
- Those getting an injection of 300,000 IU Vitamin D got out of the ICU a week sooner – RCT Dec 2020
- Traumatic Brain Injury – 120,000 IU of Vitamin D resulted in 3 fewer days on ventilators – RCT March 2020
- Better Surgical outcomes if preceded by Vitamin D loading dose – Oct 2018
- Knee replacement not helped by 2,000 IU of vitamin D (both too late and too little) – RCT July 2018
- Heart attack ICU costs cut in half by Vitamin D – Oct 2018
- Urinary sepsis – a single Vitamin D injection reduced hospital days by 40 percent – RCT April 2018
- Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT July 2017
- ICU cost reduced by at least 27,000 dollars if get high dose vitamin D in first week - April 2017
- Vitamin D and Glutamine reduced Trauma Center deaths by half – March 2017
- Hospital ICU added high dose vitamin D - malpractice lawsuit costs dropped from 26 million dollars to ZERO - Oct 2016
- Vitamin D and exercise after hip fracture surgery – far fewer deaths – July 2016
- 18 fewer hospital days if given 500,000 IU of vitamin D while ventilated in ICU – RCT June 2016
- ICU death rate reduced 3X when a vitamin D injection changed the PTH – Nov 2015
- Heart Attack ICU costs reduced $37,000 by $20 of Vitamin D – Nov 2015
- Vitamin D intervention increased by 20 percent the survival of critically ill patients- RCT June 2014
- Vitamin D aided progesterone in reducing traumatic brain injury – RCT Dec 2012
- Sepsis is both prevented and treated by Vitamin D - many studies
Having enough vitamin D minimizes the need for hip/knee replacement
- Hip fracture 50 percent more likely if low in both vitamin D and vitamin K1 – Dec 2015
- Hip fracture 3X more likely if low vitamin D – Dec 2015
- Knee joint space narrowing (Osteoarthritis) 1.5X worse with low vitamin D – meta-analysis Sept 2015
- Knee pain in seniors predicted by low vitamin D 5 years before – Feb 2014
- Hip fractures reduced 2X to 6X with just 10 minutes of sunlight daily – RCT 2003-2010
Is there an association between low serum 25-OH-D levels and the length of hospital stay in orthopaedic patients after arthroplasty?
J Orthop Traumatol. 2016 Jun 13. [Epub ahead of print]
Maier GS1, Maus U2, Lazovic D2, Horas K3, Roth KE4, Kurth AA5.
1University Hospital of Orthopaedic Surgery, Pius-Hospital, Carl von Ossietzky University, Medizinischer Campus Universität, Georgstrasse 12, 26121, Oldenburg, Germany. gerrit.maier at uni-oldenburg.de.
2University Hospital of Orthopaedic Surgery, Pius-Hospital, Carl von Ossietzky University, Medizinischer Campus Universität, Georgstrasse 12, 26121, Oldenburg, Germany.
3ANZAC Research Institute, University of Sydney, Sydney, Australia.
4Department of Orthopaedic Surgery, Johannes Gutenberg University, Mainz, Germany.
5Department of Orthopaedic Surgery, Themistocles Gluck Hospital, Ratingen, Germany.
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The purpose of this observational study was to evaluate serum levels of 25-OH-D in patients scheduled to undergo elective hip or knee arthroplasty. We hypothesised that 25-OH-D level is an independent risk factor for length of stay in orthopaedic patients after elective hip or knee arthoplasty.
MATERIALS AND METHODS:
25-OH-D levels were measured in 1083 patients admitted to an orthopaedic surgery department to undergo elective hip or knee arthroplasty. Comparisons were performed using Chi square or Student's t test, followed by univariate and multiple linear regression analysis examining the correlation between the length of stay in the orthopaedic department and 25-OH-D level while adjusting for possible confounders.
Overall, 86 % of patients had insufficient serum levels of 25-OH-D, and over 60 % were vitamin D deficient. The mean length of stay was 13.2 ± 8.3 days. In patients with hypovitaminosis D, the length of stay was significantly longer compared to patients with normal serum 25-OH-D levels (15.6 ± 7.2 compared to 11.3 ± 7.9 days, P = 0.014). In univariate analyses, serum 25-OH-D level was inversely related to the length of stay in our orthopaedic department compared to patients with normal vitamin D levels (r = -0.16; P = 0.008). In multivariate analyses, the length of stay remained significantly associated with low 25-OH-D levels (P = 0.002), indicating that low vitamin D levels increase the length of stay.
We found a high frequency of hypovitaminosis D among orthopaedic patients scheduled to undergo elective arthroplastic surgery. Low vitamin D levels showed a significant inverse association to the length of stay in our orthopaedic department. Patients with vitamin D levels in the target range were hospitalised 4.3 days less than patients with hypovitaminosis D. Level 3 of evidence according to "The Oxford 2011 levels of evidence".
Vitamin D Status and Patient Outcomes after Knee or Hip Surgery: A Meta-Analysis
Ann Nutr Metab 2018;73:121–130, https://doi.org/10.1159/000490670
Zhang H.a · Zhu X.b · Dong W.c · Wang Q.-M.d
Background: This study evaluates the effect of vitamin D status in patient outcomes after hip or knee joint surgery.
Method: Literature search was carried out in electronic databases, and study selection followed predetermined eligibility criteria. Data were extracted from relevant studies and meta-analyses of standardized mean differences between hypovitaminosis D (vitamin D deficiency or insufficiency) and euvitaminosis D in assessment scores of patient-reported outcomes were performed.
Results: A total of 12 studies (2,593 patients; age 69.89 years [95% CI 68.07–71.70]; 35.95% [29.43–42.46] males) were included in the meta-analysis. The prevalence of hypovitaminosis D (vitamin D deficiency or insufficiency) was 33.18% [25.10–41.26], but the combined prevalence of deficiency and insufficiency was 46.99 [34.02–59.96].
Hospital stay was 1.09 days [–0.39 to 2.56] longer in the hypovitaminosis D group compared to the euvitaminosis D group.
Preoperatively, Harris Hip Score (HHS) and Knee Society Score were significantly lower (p = 0.001 and p = 0.00001, respectively) in the hypovitaminosis D group than in the euvitaminosis D group.
Postoperatively, HHS (p = 0.004) score was significantly lower in the hypovitaminosis D group than in the euvitaminosis D group.
Conclusion: The prevalence of hypovitaminosis D is high in osteoarthritis patients undergoing knee or hip surgery. Vitamin D deficiency may affect the outcomes of orthopedic joint surgery. However, randomized trial/s will be required to confirm these findings.