- Efficacy of intermittent versus daily vitamin D supplementation on improving circulating 25(OH)D concentration: A Bayesian network meta-analysis of randomized controlled trials
- VitaminDWiki – Intervention - non daily category has
48 items
Efficacy of intermittent versus daily vitamin D supplementation on improving circulating 25(OH)D concentration: A Bayesian network meta-analysis of randomized controlled trials
Front. Nutr.Sec. Nutritional Epidemiology Volume 10 - 2023 | doi: 10.3389/fnut.2023.1168115 PDF not available initially
Hui Liu1, 2* Haibo Zhou1 Zhicheng Peng1 Haoyue Cheng1 Peihan Chi1 Xing Xin1 Wenliang Luo1 Shuting Si1 Minjia Mo1 Danqing Chen1 Yunxian Yu1*
1 Zhejiang University, China
2 Sir Run run shaw hospital, ChinaNMOL achieved (reminder, need >2 months to get full response)
Background: Vitamin D deficiency is a widespread issue globally, resulting in increased use of vitamin D supplements. However, it is unclear whether intermittent (weekly or monthly) vitamin D supplementation is as effective as daily supplementation in improving circulating 25-hydroxyvitamin D [25(OH)D] levels.Methods: Three databases including Medline, EMBASE, and Cochrane Library were systematically searched up to Nov 10, 2020. Risk of bias was evaluated according to Cochrane Collaboration's tool for rating methodological quality assessment. Direct and indirect comparisons between interventions and controls were performed by a Bayesian network meta-analysis (NMA), where mean difference (MD) and its 95% confidence interval (CI) was used to indicate the efficacy.
Results: This NMA analysis included 116 RCTs with a total of 11,376 participants. Generally, we observed 25(OH)D concentrations were significantly elevated regardless of vitamin D supplementation frequency. Although the findings of SUCRA indicated that daily vitamin D supplementation had a higher rank value than intermittent supplementation when the supplement dosage was similar, no statistically significant pooled mean differences of 25(OH)D concentration were noted between daily supplementation group and intermittent supplementation group.
Additionally, weekly supplementation with a total of 600,000 IU vitamin D supplementation during three months had the best efficacy in elevating 25(OH)D concentration (pooled MD=63 nmol/L, 95%CI: 49-77). To achieve optimal 25(OH)D concentration (>75 nmol/L), we recommended 60,000 IU vitamin D supplementation monthly (~2000 IU/day).Conclusion: To sum up, the efficacy of intermittent vitamin D supplementation was similar to daily supplementation. Coupled with its convenience, frequency and dosage of intermittent vitamin D supplements were recommended to reach optimal 25(OH)D 4 level.
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VitaminDWiki – Better than Daily contains
33 items in BETTER THAN DAILY category Non-daily (Bolus) is better:
- Better compliance for everyone
- Fewer opportunities to forget.
- If happen to forget, just take the dose many days later
- Fewer times to have to take a pill - for those who dislike doing so
- Non-daily gets more vitamin D to the cells for the ~20% who have a poor Vitamin D Receptor
- A high concentration gradient is one of 14+ ways to get past Vitamin D Receptor limitations
- So, while 80% get no extra benefit from non-daily dosing, 20% will get an extra benefit
- Weekly Vitamin D better than daily – lower cost, less pill burden, perhaps 1.5X better response – meta-analysis Oct 2024
- Vitamin D given daily, weekly, or monthly has similar response (116 RCTs) – meta-analysis Aug 2023
- 44 percent of successful RCTs in VitaminDWiki used non-daily dosing - Nov 2020
- Monthly vitamin D dosing better for children than daily (again) - Oct 2023
VitaminDWiki – Intervention - non daily category has
48 items - wiki page:
- Type 1 Diabetic inflammation reduced by 50 ng of Vitamin D - Dec 2024
- Clinically isolated syndrome (a precursor to MS) reduced 34% by bi-weekly 100,000 IU of vitamin D – Sept 2024
- Obese women had larger response to oral v.s. injected Vitamin D – Jan 2024
- Children had a better response to Vitamin D given every 2 weeks than daily – RCT Aug 2024
- Viral infections reduced 40% by monthly 100,000 IU Vitamin D – RCT review Aug 2024
- Long-COVID fatigue, anxiety, and cognition treated by 60,000 IU of vitamin D weekly – RCT July 2024
- 50,000 IU of Vitamin D monthly is safe for 1 year, levels still rising – June 2024
- Single 600,000 IU dose of nanoemulsion Vitamin D is safe and effective to fight COVID, even if delay until enter ICU – RCT May 2024
- Children with ADHD again helped by 50,000 IU weekly Vitamin D – RCT June 2024
- COVID deaths cut in half by a single dose of 600,000 IU of Vitamin D - RCT Jan 2024
- PMS reduced by 50,000 IU every two weeks - RCT Jan 2024
- Vitamin D loading dose of 30,000 IU twice a week is safe and effective – RCT July 2023
- Monthly vitamin D dosing better for children than daily (again) - Oct 2023
- Muscles improved in women with 50,000 IU vitamin D weekly (8 weeks) plus daily Magnesium – RCT Sept 2020
- Fibromyalgia pain, fatigue, etc. reduced by 50,000 IU of Vitamin D for 12 weeks – Sept 2023
- Senior cognition improved in 4 ways by Vitamin D (50,000 IU weekly for 8 weeks) – Sept 2023
- Chronic Periodontitis reduced by Vitamin D (60,000 IU weekly for 8 weeks) – RCT July 2023
- Less morphine recall if preceded by twice a week Vitamin D (400 IU per kg in rats, human weights 80 kg) – Aug 2023
- Breast Cancer survival: 44% with just 10,000 IU of vitamin D per week, 33% with placebo – RCT Dec 2023
- Vitamin D response independent of dosing interval – meta-analysis July 2023
- Pain not reduced by 60,000 IU monthly vitamin D (need 50,000 IU weekly) – RCT Aug 2023
- Depression cost-effectively reduced by 50,000 IU of Vitamin D monthly (Iranian teens) – July 2023
- Cardiovascular events – need more than monthly 60,000 IU vitamin D to prevent other than infarction – June 2023
- Multiple Sclerosis treated equally by UVB and weekly 50,000 IU of Vitamin D – RCT July 2023
- Bone fractures of children not reduced if given little vitamin D, no Calcium etc. – RCT May 2023
- Tuberculosis not prevented by a tiny amount of vitamin D (equiv to 1,400 IU daily) – RCT May 2023
- Chronic tonsillitis virtually eliminated in children by Vitamin D (50,000 IU weekly) – RCT May 2023
- Response to infant 2,000 IU Vitamin D daily was in 194 ng, monthly dosing was 20% less – RCT May 2023
- Smoking does not decrease response to monthly Vitamin D – RCT July 2020
- Depression is especially reduced by large intermittent doses of vitamin D – meta-analysis – April 2023
- Fracture 4X less likely following kidney transplant if high-dose Vitamin D (100,000 every 2 weeks) – RCT Jan 2023
- Lupus: 60,000 IU Vitamin D monthly got to only 34 ng, not enough to help – RCT Jan 2023
- Anxiety and Depression decreased in senior prediabetics with weekly 25,000 IU of Vitamin D – RCT Sept 2022
- Depression decreased by Vitamin D (12th study in VitaminDWiki) – RCT Nov 2022
- Bone biomarkers increased equally by daily, weekly, or monthly Vitamin D (CKD in children in this case) – Nov 2022
- Immune systems of overweight black women improved by monthly 60,000 IU Vitamin D – RCT Oct 2022
- Vitamin D does not help when most are not deficient (cataract surgery in this case) – RCT Sept 2022
- Diabetic inflammation synergistically decreased by Vitamin D and exercise – RCT June 2022
- Vitamin D treatment of Chronic Kidney Disease: monthly better than daily – RCT May 2022
- BPH (PSA) decreased by Vitamin D (50,000 IU bi-weekly) – RCT Nov 2020
- Several rheumatic diseases treated by high-dose vitamin D, but made worse if Calcium was added – April 2022
- Diabetes prevented by 50,000 IU vitamin D monthly (Iran) – Jan 2022
- Monthly vitamin D helped hearts with low vitamin D a bit (need it more frequently) – RCT March 2022
- HIV treatment augmented by high-dose vitamin D, daily or weekly – Dec 2021
- Monthly 120,000 IU of Vitamin D while breastfeeding was good – RCT Jan 2022
- Several smoking problems treated by Vitamin D (bi-weekly, 50,000 IU) - RCT Dec 2021
- Most Diabetics getting 40,000 IU of vitamin D weekly did not get to 30 ng (needed gut-friendly form) - RCT June 2020
- Vitamin D levels in teens restored with 150,000 IU monthly for 3 months (mean 33 ng) – Oct 2021
- Sleep not helped when half got to 35 ng of Vitamin D (may need 60 ng) – RCT Dec 2021
- TB not prevented by a small amount of Vitamin D (2,000 IU daily average, Mongolia) – RCT July 2020
- Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021
- Weekly Vitamin D plus daily Magnesium is great (reduced depression in obese women in this case) – July 2021
- Falls not decreased by 60,000 IU Vitamin D monthly (not a news item) – RCT Aug 2021
- COVID-19 mortality reduced 4X (chart looks like 2X) by large, infrequent doses of Vitamin D in France – July 2021
- Pain reduced by Vitamin D (60K weekly, then monthly) plus daily Calcium in 3 months – May 2021
- Asthma and COPD in a few seniors greatly decreased by monthly 100,000 IU Vitamin D – RCT Feb 2021
- Mild Obstructive Sleep Apnea decreased by 50,000 IU weekly vitamin D – June 2021
- Every schizophrenia measure was improved when vitamin D levels were normalized – June 2021
- Immune systems helped by 50,000 IU of vitamin D (weekly for 3 months) – May 2021
- 54 genes significantly affected by Vitamin D (50,000 IU weekly for 12 weeks) – May 2021
- 50,000 IU of Vitamin D once every 2 weeks achieved 40 ng in 3 months – RCT March 2021
- Fewer children died of pneumonia after 100,000 IU Vitamin D injection – RCT March 2021
- Stroke patients getting weekly 50,000 IU Vitamin D did better – trial March 2021
- 5X less likely to enter ICU with COVID-19 if get Calcifediol (semi-activated vitamin D) - RCT Feb 19, 2021
- calcifediol rct
- Half as many problems if take Vitamin D (300,000 IU) before thyroidectomy – RCT Jan 2021
- Endometriosis treated by Vitamin D (50,000 IU bi-weekly) – RCT Jan 2021
- Smokers helped by Vitamin D (100,000 IU monthly) - RCT Dec 2017
- Weekly response to semi-activated vitamin D slightly better than standard – RCT Nov 2019
- Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021
- Acute respiratory tract infections not reduced by Vitamin D if already have a good level – Jan 2021
- Vitamin D for infants – 100,000 IU monthly is better than 400 IU daily – RCT Oct 2020
- BPH (PSA) decreased by Vitamin D (50,000 IU bi-weekly) – RCT Nov 2020
- COVID-19 defeated 3x faster by 420,000 IU Vitamin D nanoemulsion – RCT Nov 12, 2020
- 44 percent of successful RCTs in VitaminDWiki used non-daily dosing - Nov 2020
- ICU patients greatly helped by Vitamin D loading doses – if gut-friendly – Oct 2020
- In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly – Dec 2024
- Diverticular disease:12X reduction if low Vitamin D and given 100,000 IU monthly – RCT Aug 2020
- Sperm not improved enough by Vitamin D - 50,000 IU weekly for 8 weeks - RCT Aug 2020
- Monthly 100,000 IU of Vitamin D adds about 25 ng - RCT April 2020
- Diabetic inflammation reduced by Vitamin D (30,000 IU weekly) – RCT July 2020
- 50,000 IU Vitamin D weekly was the most popular for Breast Cancer - May 2020
- Weekly 50,000 IU of vitamin D is again found to be good – RCT May 2020
- IBS diarrhea treated by weekly 50,000 IU of Vitamin D – RCT March 2020
- 50,000 IU Vitamin D weekly provided enough benefit for combat sport athletes – March 2020
- Those with Asthma or COPD had half the response to Vitamin D – March 2020
- 53 Multiple Sclerosis patients somewhat helped by 10,000 IU of vitamin D (vs, 30,000 virtually cured by 10X as much) – Jan 2020
- 20,000 IU of Vitamin D weekly gave many benefits – RCT Aug 2019
- Multiple Sclerosis relapses cut in half by 100,000 IU of Vitamin D every 2 weeks– RCT 2019
- Influenza vaccine antibodies not change with Vitamin D – 21 ng or 44 ng – RCT Feb 2019
- 100,000 IU of Vitamin D3 monthly for 4 months to diabetics (D2 bombed) – RCT Dec 2019
- Muscles not improved by just Vitamin D weekly (also need exercise) – Dec 2019
- Yet another study confirms Depression is treated by weekly Vitamin D (50,000 IU)– RCT Dec 2019
- HIV therapy reduces Vitamin D levels, supplementation helps - Nov 2019
- PMS again significantly reduced by 50,000 IU of vitamin D (This time, every two weeks) – RCT Oct 2019
- Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT Oct 2019
- Vitamin D levels in children optimized with six Vitamin D biscuits – RCT Nov 2018
- Hashimoto's thyroiditis helped by weekly 50,000 IU of vitamin D – RCT May 2019
- Obese lost 3X more weight with Vitamin D - July 2018
- Breast Cancer chemo reduces Bone Mineral Density, injecting Vitamin D increases it – Sept 2019
- Colorectal Cancer treatment aided by omega-3 plus weekly Vitamin D – RCT Sept 2019
- Severely Obese not helped much by 50,000 IU of vitamin D weekly for 8 weeks – RCT June 2019
- Athletes helped by weekly 50,000 IU Vitamin D – RCT Aug 2019
- Hay Fever treated by Vitamin D (50,000 IU weekly) – RCT July 2019
- COPD trial to use 80,000 IU of vitamin D weekly – RCT 2021
- Type 2 Diabetes inflammation reduced by 50,000 IU of Vitamin D bi-weekly and resistance training – RCT – June 2019
- Lower back pain treated by 600,000 IU of Vitamin D – RCT June 2019
- Methadone cognition improved by 50,000 IU of vitamin D every 2 weeks – RCT May 2019
- Weekly oral Vitamin D recommended before surgery (Bariatric in this case) – RCT June 2019
- Grip strength following wrist fracture increased by 50,000 IU Vitamin D monthly – May 2019
- Obese responded to weekly vitamin D better than non-obese – RCT March 2018
- Weekly Vitamin D to mother after birth much better than daily - RCT Aug 2018
- Irritable Bowel Syndrome treated by weekly 50,000 IU Vitamin D – RCT Feb 2019
- Prediabetes both prevented and treated by monthly Vitamin D, etc.
- Cystic Fibrosis not helped by 50,000 IU of Vitamin D taken twice a month – RCT Feb 2019
- Schizophrenia reduced by biweekly 50,000 IU Vitamin D and probiotics – RCT Feb 2019
- Vitamin D every 14 weeks is not often enough (asthma in this case)– Feb 2019
- Cognitive function of adult women improved in 3 months of 50,000 IU weekly Vitamin D – Jan 2019
- 450,000 IU of vitamin D over 9 weeks given to 100,000 teenage Iranian girls helped their livers – Feb 2019
- Childhood colds reduced 25 percent by weekly Vitamin D – RCT Jan 2019
- Peripheral diabetic neuropathy helped by weekly 50,000 IU vitamin D – Jan 2019
- Urgency Urinary Incontinence in senior black women decreased 40 percent by weekly 50,000 IU vitamin D – RCT Dec 2018
- Ulcerative Colitis inflammation treated by weekly vitamin D (40,000 IU) – July 2018
- Daily, monthly Vitamin D had similar great benefits, more than 6 months needed – RCT Dec 2018
- 50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014
- Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT Nov 2018
- Rheumatoid Arthritis pain reduced by monthly 100,000 IU of Vitamin D – Oct 2018
- Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT Jan 2019
- Obese lost more weight on diet if added 50,000 IU of vitamin D weekly – many RCTs
- Getting Vitamin D before heart surgery prevented Afib in those who had been deficient – July 2018
- Esophageal Cancer surgery helped by 300,000 IU of Vitamin D – RCT Sept 2018
- Vitamin D dosing - weekly may be better than daily – video Aug 2018
- 50,000 IU of Vitamin D weekly for 9 weeks did not improve CVD – Aug 2018
- Monthly 100,000 IU of vitamin D is safe (and may be better than daily) – RCT Aug 2018
- Vitamin D given weekly better than daily (Nursing home, 5,600 IU weekly) – Aug 2018
- All asthma problems reduced after 1 year of Vitamin D – Nov 2017
- Knee Osteoarthritis benefited by 20 ng of Vitamin D for 5 years – RCT July 2018
- Multiple Sclerosis treated by 50,000 IU Vitamin D bi-weekly plus Omega-3 – RCT July 2018
- Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT June 2018
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018
- Fibromyalgia pain substantially reduced by weekly Vitamin D (50,000 IU) – June 2018
- Pregnancies helped a lot by Vitamin D (injection then 50,000 IU monthly) – RCT May 2018
- 100,000 IU of vitamin D monthly decreases use of NASIDs by 13 percent if low vitamin D – RCT May 2018
- Vitamin D every 25 days may be BETTER than daily – RCT May 2018
- 300,000 IU of Vitamin D is not enough during pregnancy – RCT May 2018
- Cardiovascular risk markers not helped by 20,000 IU of vitamin D weekly – RCT May 2018
- Vitamin D weekly supplementation (Spinal Cord Injury athletes) increased handgrip strength – May 2018
- Gut bacteria of Crohn's disease patients improved by Vitamin D – March 2018
- Response by obese to weekly 50,000 IU of Vitamin D – May 2018
- Far more Vitamin D in breast milk from a 150,000 IU dose than from daily 5,000 IU – RCT May 2018
- Autism treated by Vitamin D (monthly injection of 150,000 IU) – June 2017
- Weekly dosing of vitamin D is far better than single large dose (chronic liver, children) – March 2018
- Monthly vitamin D dosing had higher response than 3 per month – RCT Jan 2018
- Testosterone and erectile function increased after vitamin D supplementation – Jan 2018
- PMS in teens reduced 3X by 50,000 IU vitamin D weekly – Jan 2018
- Waist size reduced 3 cm by Vitamin D in those with Metabolic Syndrome – Jan 2017
- Lupus reduced when half of participants got to 38 ng of Vitamin D (not statistically significant) – RCT Jan 2017
- HbA1c levels (Diabetes) reduced by monthly 50,000 IU of vitamin D – Dec 2017
- Breathing by ever-smokers improved by monthly Vitamin D – RCT 2017
- Ventilator-associated pneumonia death rate cut in half by Vitamin D injection (300,000 IU) – RCT July 2017
- Vitamin D depression RCT canceled: too many were taking Vitamin D supplements, etc. Feb 2018
- Vitamin D changed microbiota in gut and airway, might reduce cystic fibrosis – RCT Nov 2017
- Hypertension not controlled by 26 ng of Vitamin D (50,000 IU bi-weekly A-A) – RCT Nov 2017
- Less bone loss if take 100,000 IU vitamin D monthly – RCT Nov 2017
- Vitamin D toxicity problems from 600,000 IU weekly for 6 weeks – July 2017
- Blood pressure reduced by monthly 100,000 IU of vitamin D in those who were deficient – RCT Oct 2017
- Probably Fractures of the Tibia can be healed with 100,000 IU of vitamin D weekly – RCT 2023
- Promising Vitamin D Clinical Trials - 2017
- Perhaps fewer bone non-unions with 100,000 IU weekly of vitamin D – RCT 2018
- Breast Cancer trial using 50,000 IU Vitamin D weekly cancelled (no funding)
- Delay onset of Multiple Sclerosis with 100,000 IU of vitamin D every two weeks – RCT 2020
- Vitamin D taken daily (4,000 IU) vs weekly (50,000 IU) – RCT 2019
- HIV patients helped by monthly 120,000 IU of Vitamin D – RCT Oct 2017
- Monthly 120,000 IU Vitamin D plus daily Calcium was great during pregnancies – RCT Sept 2017
- Intervention - non daily
- Monthly 80,000 IU of vitamin D safely got half above 40 ng in 6 months – March 2017
- Vitamin D – 91 percent safely got above 30 ng in 2 months with weekly 30,000 IU – Aug 2017
- TB not treated by vitamin D given for only 2 months – RCT Sept 2017
- Monthly vitamin D dosing is better than daily dosing for children and elderly (more likely to be taken) – June 2017
- Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017
- Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D – Jan 2017
- Canadian grant funding lost for prescribing 50,000 IU of vitamin D – July 2017
- Preeclampsia recurrence reduced 2 X by 50,000 IU of vitamin D every two weeks – RCT July 2017
- Chinese women in tropics needed 50,000 IU of Vitamin D monthly to keep above 30 ng – RCT May 2017
- 50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT July 2017
- Many benefits of 50,000 IU vitamin D every two weeks (methadone treatment) – RCT June 2017
- Breastfeeding mothers and Vitamin D: supplement only themselves usually, 4 out of 10 used monthly rather than daily – Jan 2017
- Sleep disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT May 2017
- Vitamin D – 50,000 IU monthly is enough if near the equator and have normal weight – May 2017
- Elite Athletes do well with weekly 35,000 IU of Vitamin D – RCT Feb 2017
- Optimal vitamin D supplementation strategies (D3 - weekly or monthly) – Feb 2017
- Pulmonary hypertension reduced in some people with weekly 50,000 IU vitamin D for 3 months – 2016
- Vitamin D required for breastfed infants – daily or monthly, infant or mother – Jan 2017
- Chronic Back Pain relieved by weekly 60,000 IU of vitamin D – Jan 2017
- 50,000 IU of vitamin D for 8 weeks of pregnancy raised most above 30 nanograms - RCT Jan 2017
- Knee osteoarthritis pain reduced by 60,000 IU monthly vitamin D following loading dose – RCT Nov 2013
- Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – 2016, 2017, 2018, 2019
- Chikungunya virus arthritis pain reduced by weekly 60,000 IU vitamin D – Sept 2016
- Vitamin D – monthly dosing was better than daily with Calcium – RCT Dec 2015
- Multiple sclerosis helped some by 10,000 IU of vitamin D daily avg. for 3 months – RCT Sept 2016
- Gestational Diabetes treated with 50,000 IU every two weeks – RCT Sept 2016
- Mother got 100,000 IU of vitamin D monthly, breastfeeding infant got a little – RCT Aug 2016
- Ischaemic stroke – Vitamin D doubled survival (Injection followed by monthly 60,000 IU) – RCT Aug 2016
- Weekly pizza fortified with 28,000 IU raised Vitamin D by 30 nanograms – RCT Aug 2015
- Pregnancy – adding 35,000 IU Vitamin D weekly was nice, but not enough – RCT April 2016
- Non-Alcoholic Fatty Liver Disease (NAFLD) treated by Vitamin D (20,000 IU weekly after loading dose) – RCT June 2016
- UTI associated with low Vitamin D as well as treated - many studies
- Falls cut in half by 100,000 IU vitamin D monthly - RCT 2016
- Nursing home residents need Vitamin D 4,000 IU daily or 50,000 IU weekly – Jan 2016
- Infant infection reduced by half with vitamin D supplementation – RCT May 2016
- IBS quality of life improved by vitamin D (50,000 IU every two weeks) – RCT May 2016
- Vitamin D daily or weekly dosing resulted in similar response -RCT Jan 2016
- 5,000 IU daily or 50,000 IU Vitamin D weekly repleted many dark skinned adolescents – RCT Dec 2015
- Vitamin D loading dose then weekly 50,000 IU not help (COPD) if very deficient – Oct 2015
- Preeclampsia reduced by Vitamin D (50,000 IU bi-weekly) and Calcium – Oct 2015
- Common cause of dizziness (BPPV) reduced 5 X by several doses of 50,000 IU of vitamin D – 2015, 2016
- Children getting 60,000 IU monthly got to vitamin D level of 33 ng – Sept 2015
- Graph of weekly response to monthly vitamin D supplementation – Aug 2015
- 2X fewer Senior falls in group getting 100,000 IU vitamin D monthly via Meals-on-Wheels – RCT Aug 2015
- Migraine headaches reduced with 50,000 IU vitamin D weekly – RCT July 2015
- 50,000 IU of vitamin D weekly (D3 or D2) got two thirds of cystic fibrosis patients to 30 nanograms – RCT July 2015
- Vitamin D levels of HIV and non HIV equally restored with 50,000 IU twice a week - July 2015
- Hives treatment augmented by 60,000 IU Vitamin D weekly – RCT June 2015
- No multiple sclerosis relapses during pregnancy if 50,000 IU of Vitamin D weekly – RCT April 2015
- Non-alcoholic fatty liver disease (NAFLD) reduced somewhat by 50,000 IU vitamin D every 2 weeks – RCT Sept 2014
- Knee osteoarthritis treated with vitamin D, weekly 50,000 IU – May 2015
- Juvenile Lupus fatigue reduced by vitamin D ( 50,000 IU weekly for 6 months) – RCT May 2015
- Prediabetes reduced by monthly 60,000 IU of vitamin D – RCT May 2015
- Respiratory infections (RTI) cut in half by 20,000 IU weekly vitamin D if initially deficient – RCT March 2015
- Pain of Diabetic Neuropathy reduced with weekly 50,000 IU vitamin D– CT Feb 2015
- Response and adverse effects of 20,000 and 30,000 IU Vitamin D weekly - Feb 2015
- 50,000 IU of Vitamin D every 2 weeks reduced gestational diabetes – RCT Feb 2015
- T-cells increased with monthly doses of 140,000 IU vitamin D – April 2014
- Angina dramatically reduced by injections of vitamin D twice a month (300,000 IU) – Jan 2015
- Response to 150,000 IU vitamin D once vs 5,000 IU daily – RCT May 2014
- Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks – Nov 2014
- Growing pains reduced 60 percent by monthly Vitamin D – March 2014
- Fibromyalgia pain with trazodone reduced by 50 percent with weekly 50,000 IU of vitamin D – RCT Nov 2014
- Vitamin D restored in teens by doses totalling 300,000 IU – Nov 2014
- ICU survival increased with vitamin D single 540K IU loading dose - JAMA Sept 2014
- Asthma reduced by weekly 50,000 IU of vitamin D – RCT Aug 2014
- Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT June 2014
- Optic neuritis progession into Multiple Sclerosis reduced 68 percent by 50,000 IU of vitamin D weekly
- Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT Jan 2014
- One pill every two weeks gives you all the vitamin D most adults need
- Vitamin D update – 40-60 ng ideal, 50K biweekly maintenance – Jan 2014
- Can get 50,000 IU Vitamin D anywhere on the globe
- Rickets prevented by single injection of vitamin D or weekly supplementation – RCT Jan 2014
- 50,000 IU of vitamin D monthly in winter gets most above 20 ng – RCT Nov 2013
- Breast milk resulted in 20 ng of vitamin D for infant if mother had taken 5,000 IU daily – RCT Dec 2013
- 40,000 IU vitamin D weekly reduced depression in many obese subjects – RCT 2008
- COPD fought by Vitamin D - many studies
- HIV – recommend 100,000 IU vitamin D monthly to get levels 30 ng – May 2013
- Antibiotic use cut in half by elderly (over 70) after monthly 60,000 IU of vitamin D – RCT Dec 2013
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
- Prenatal Vitamin D (35,000 weekly, 3rd trimester) resulted in 1 cm taller infants at age 1 year – RCT Aug 2013
- Insulin resistance during pregnancy improved with 50,000 IU of vitamin D every 2 weeks – RCT April 2013
- 50,000 IU vitamin D 1-3 times per week helped obese patients in rehab. – May 2013
- Near the end of pregnancy 50,000 IU vitamin D weekly was great – RCT April 2013
- 35,000 IU vitamin D weekly during 3rd quarter pregnancy – RCT March 2013
- 50,000 IU vitamin D weekly is safe and effective for Primary Hyperparathyroidism – Jan 2013
- Venous ulcers healed 4X faster with weekly 50,000 IU vitamin D – RCT Oct 2012
- 7100 IU (50000 weekly) got most women to 30 ng of vitamin D - Aug 2012
- 7100 IU (50000 weekly) restored vitamin D levels for those with Chronic Kidney Disease – July 2012
- 7 improvements in lives of veterans with chronic pain with 50,000 IU vitamin D weekly – June 2012
- Raynaud's pain decreased with 600,000 IU monthly vitamin D – RCT May 2012
- Take vitamin D3 daily, weekly, or bi-weekly
- Proof that Vitamin D Works
- Muscle strength in youth increased with 60,000 IU vitamin D per week and 1 g Calcium – April 2010
Vitamin D response independent of dosing interval – meta-analysis July 2023(Cached) Printer Friendly Follow this page for updates2617 visitors, last modified 13 Dec, 2023, This page is in the following categories (# of items in each category)Attached files
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