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Some Rickets is due to poor genes - Vitamin D needed lifelong – June 2020

Diagnosis and Management of Vitamin D Dependent Rickets

Front. Pediatr., 12 June 2020 | https://doi.org/10.3389/fped.2020.00315
Michael A. Levine*
Center for Bone Health and Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States


Rickets almost eradicated in counties giving free Vitamin D, perhaps the world can learn – Dec 2019

Overview of Rickets and vitamin D contains the following summary
Rate of rickets is usually < 0.1% of births, unless dark skin or breastfed
Rate of rickets has greatly increased with the drop in vitamin D levels during the past 40 years
400 IU can prevent/treat most rickets Turkey gave vitamin D to EVERY child and eliminated Rickets
A low serum level of vitamin D does not indicate rickets
Sometimes rickets is also associated with a poor vitamin D receptor
Giving enough Vitamin D to the mother PREVENTS Rickets
Rate of rickets in some countries varies from 10% to 70% (typically poor health overall)
Rickets has been more than doubling in many countries
Rickets is strongly associated with severe breathing problems (weak ribs)
Bowed legs is not the primary indication of rickets (3 other indications of rickets are seen more often)
Vitamin D and Rickets consensus took 80 years

Rickets category has 122 items

Genetics has the following chart
Blood Test Misses a lot (VDW 3439)

The items in both Rickets and Genetics are listed here:

The items in both Rickets and Vitamin D Receptor are listed here:

 Download the PDF from VitaminDWiki

Note by VitaminDWiki - Vitamin D values seem to be about 40X too large - perhaps should be IU, not micrograms

The term “vitamin D dependent rickets” describes a group of genetic disorders that are characterized by early-onset rickets due to the inability to maintain adequate concentrations of active forms of vitamin D or a failure to respond fully to activated vitamin D. Although the term is now admittedly a pathophysiological misnomer, there remains clinical relevance for its continued use, as patients have a lifelong “dependency” on administration of specialized regimens of vitamin D replacement. This review provides an update on the molecular bases for the three forms of vitamin D dependent rickets, and summarizes current protocols for management of affected subjects.

Created by admin. Last Modification: Wednesday July 1, 2020 17:34:33 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
13972 Rickets T2.jpg admin 01 Jul, 2020 17:15 97.97 Kb 127
13971 Rickets diagnostic.jpg admin 01 Jul, 2020 17:15 74.94 Kb 135
13970 Rickets Vit D and continue thru life.pdf PDF 2020 admin 01 Jul, 2020 17:09 564.64 Kb 162
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