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The CYP27B1 gene activates Vitamin D in the Kidney,    Skin,    Lungs,    Brain,   Eyes   Breasts   etc.
Poor CYP27B1 is assocated with COVID, Miscarriage,   Lupus,   Alz, Parkinson, MSA,   Rickets

CYtochrome P450 family 27 subfamily B member 1    = 25-Hydroxyvitamin D3 1-alpha-hydroxylase

What can be done if have a poor CYP27B1

  • Larger doses of Vitamin D
  • More Bio-available: Gut-friendly form, Topical form, taken with fatty meal, taken with evening meal
  • Additional sources: UV
  • Increase Vitamin D metabolism: additional Magnesium, Omega-3
    • All cytochrome P450 enzymes require Mg++ as a cofactor
  • Increase the amount of Vitamin D in the blood that gets to cells: increase activation of VDR

Vitamin D blood test misses CYP27B1 and other genes
in Visio for 2023

Here are all of the CYP27B1 articles

See also web

  • Gene therapy for CYB27B1extended the lives of mice with acute myeloid leukemia - compared to placebo
    • A novel vitamin D gene therapy for acute myeloid leukemia
    • Behind paywall DOI: 10.1016/j.tranon.2020.100869 Sept 2020
  • Higher risk of Atrial fibrilation of poor CYP27B1
    • Vitamin D Status in Patients with Atrial Fibrillation and Heart Failure - Is there a Link? - June 2021
    • Details are behind a paywall @ DOI: 10.7754/Clin.Lab.2020.200902

CYP27B1 Associations: Genetics 37, Vitamin D Receptor 33, Vit D Binding Protein 21, Cancer - Breast 4, Pregnancy 4, Vision 3 Cognitive 3, UV 3

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