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Epigenetics - PDFs and links, with and without Vitamin D

Human Epigenetics: How Science Works - PDF of 2019 book

New textbook explains human epigenetics to undergraduates
Carlberg, Carsten, Molnár, Ferdinand, DOI 10.1007/978-3-030-22907-8
Chromatin
DNA Methylation
Histone Modifications|
Chromatin Modifying Proteins and RNAs
Embryogenesis and Cellular Differentiation
Population Epigenetics and Aging
Cancer Epigenetics
Neuroepigenetics
Nutritional Epigenetics
Epigenetics of Immune Function
Epigenome-Environment Interactions and Their Therapy
 Download the PDF from Sci-Hub via VitaminDWiki

Strangely, "Vitamin D" is not mentioned in his book even once

A few images from the book
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A few of Carlberg, Carsten Vitamin D Studies

  • Vitamin D Signaling in the Context of Innate Immunity: Focus on Human Monocytes – Sept 2019 Free PDF doi: 10.3389/fimmu.2019.02211
    • “Thus, the epigenome of human monocytes is at multiple levels sensitive to vitamin D”
  • Vitamin D and evolution: Pharmacologic implications – Aug 2019 doi: 10.1016/j.bcp.2019.07.024
  • Vitamin D Nutrigenomics - High, Medium, and Low Responders - March 2019 on VitaminDWiki

Vitamin D: a Review of its Effects on Epigenetics and Gene Regulation – 2020

Folia Med (Plovdiv) . 2020 Dec 31;62(4):662-667. doi: 10.3897/folmed.62.e50204..
Violeta Snegarova 1, Darina Naydenova 2

Vitamin D is a secosteroid hormone with known beneficial effects on several body systems other than the musculoskeletal system. Both 25 dihydroxy vitamin D [25(OH)2D] and its active hormonal form, 1,25-dihydroxyvitamin D [1,25(OH)2D] are essential for hu-man physiological functions, including damping down inflammation and the excessive intracellular oxidative stresses. In the present study we set out to review all available literature on vitamin D and the role it plays in epigenetics and gene regulation. We searched the PubMed/Medline electronic database for studies published in the English language up to January 2020. The Medical Subject Headings (MeSH) database was searched with the keywords 'vitamin D', 'DNA methylation', 'nutritional supplements', 'epigenome' and 'pregnancy'. Observational studies, supplementation studies, and meta-analyses dealing with the effect of vitamin D on epigenetics and gene regula-tion were included in the review. The obtained information from the databases such as PubMed, Google Scholar, and ResearchGate was analysed and summarized.
We found that hypovitaminosis D increases the incidence and severity of several age-related common diseases such as the oxidative stress-associated metabolic disorders.
These include

  • obesity,
  • insulin resistance,
  • type 2 diabetes,
  • hypertension,
  • pregnancy complications,
  • memory disorders,
  • osteoporosis,
  • autoimmune diseases,
  • certain cancers, and
  • systemic inflammatory diseases.

New understandings of vitamin D-related advances in metabolomics, transcriptomics, epigenetics, in relation to its ability to control oxidative stress in conjunction with micronutrients, vitamins, and antioxidants, following normalization of serum 25(OH)D and tissue 1,25(OH)2D concentra-tions, are likely to promise better cost-effective clinical outcomes in humans. There is a strong reciprocity between the vitamin D system and epigenetic mechanisms. The vitamin D system is, on the one hand regulated by epigenetic mechanisms and, on the other hand, is involved in regulating epigenetic events.
 Download the PDF from VitaminDWiki


Some Epigenetic items on the web - Dec 2019

Title revision of Dec 2019 caused the visitor count to reset.
There have actually been 1524 visitors to this page since it was originally made


Created by admin. Last Modification: Thursday February 25, 2021 14:36:04 GMT-0000 by admin. (Version 17)

Attached files

ID Name Comment Uploaded Size Downloads
15119 Epigenetics and Gene Regulation 2020.pdf PDF 2020 admin 25 Feb, 2021 14:28 171.68 Kb 75
13213 Vitamin D, Testosterone, Epigenetics RG.pdf admin 23 Dec, 2019 13:18 2.11 Mb 254
13212 VDR Epi.pdf admin 23 Dec, 2019 13:14 1.54 Mb 224
13211 Vitamin D and the epigenome June 2014.pdf admin 23 Dec, 2019 13:07 710.22 Kb 213
13210 Epigenetics June 2018.pdf PDF 2018 admin 23 Dec, 2019 13:01 1.10 Mb 251
12810 Epi changes.jpg admin 17 Oct, 2019 10:18 28.49 Kb 430
12809 Epi mechanisms.jpg admin 17 Oct, 2019 10:18 84.66 Kb 413
12808 Epi modifiers.jpg admin 17 Oct, 2019 10:17 74.49 Kb 387
12807 Epi 10.6.jpg admin 17 Oct, 2019 10:17 50.75 Kb 395
12806 Epigenetics sci-hub_compressed.pdf PDF 2019 admin 17 Oct, 2019 10:01 9.39 Mb 441
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