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Poor vision associated with poor Vitamin D or poor Vit. D genes – June 2022

Nutrients 2022, 14(11), 2353; https://doi.org/10.3390/nu14112353
by Miłosz Caban and Urszula Lewandowska *ORCID
Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Kosciuszki 4, 90-419 Lodz, Poland

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Chart of vision and genes



The global prevalence of eye diseases continues to grow, bringing with it a reduction in the activity levels and quality of life of patients, and partial or complete blindness if left untreated. As such, there is considerable interest in identifying more effective therapeutic options and preventive agents. One such agent is vitamin D, known to have a range of anti-cancer, anti-angiogenic, anti-inflammatory and anti-oxidative properties, and whose deficiency is linked to the pathogenesis of a range of cardiovascular, cancer, and inflammatory diseases. This review presents the current stage of knowledge concerning the link between vitamin D and its receptor and the occurrence of eye disease, as well as the influence of analogues of calcitriol, an active metabolite of vitamin D. Generally, patients affected by various ocular disorders have vitamin D deficiency. In addition, previous findings suggest that vitamin D modulates the course of eye diseases and may serve as a marker, and that its supplementation could mitigate some disorders. However, as these studies have some limitations, we recommend further randomized trials to clarify the link between vitamin D and its activity with eye disease.
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17756 Vision study8.jpg admin 05 Jun, 2022 14:32 38.92 Kb 123
17755 Vision study7.jpg admin 05 Jun, 2022 14:32 371.46 Kb 131
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17750 Vision study2.jpg admin 05 Jun, 2022 14:30 118.97 Kb 120
17749 Vision study1.jpg admin 05 Jun, 2022 14:30 157.87 Kb 122
17748 Vision ToC.jpg admin 05 Jun, 2022 14:30 45.16 Kb 118
17747 Vision and Vitamin D genes.jpg admin 05 Jun, 2022 14:29 112.40 Kb 133
17746 VDR vision.pdf PDF 2022 admin 05 Jun, 2022 14:29 847.46 Kb 84