Revue d'Épidémiologie et de Santé Publique, Volume 66, Supplement 5, July 2018, Page S237
Telomere length is seen as marker for healthy ageing, as accelerated shortening is involved in the development of age-related diseases, including cardiovascular disease. Vitamin D might influence telomere length due to anti-inflammatory activities, because inflammation could decrease telomere length. Evidence supporting this theory is mainly from studies in adults, whether vitamin D in children is a predictor of telomere length is unknown. Therefore, this study investigated the role of vitamin D on telomere length in the transition from childhood to (early) adolescence.
Healthy Belgian children (n = 142) were followed-up between 2010–2015 (aged 4.7–10.7 years old at baseline, 50.4% boys). Serum vitamin D (25-hydroxy vitamin D) concentrations were measured at baseline and in 2015 using standardized protocols. Average relative telomere lengths were measured in blood samples using a quantitative real-time PCR method. Cross-sectional and longitudinal age and sex adjusted mixed linear regression models addressed the association between vitamin D and telomere length.
This study over a 5-year period suggests that higher vitamin D concentrations are associated with longer telomere length in boys. These findings highlight the potential beneficial effects of vitamin D on ageing, especially since vitamin D concentrations might be easily adjustable through nutritional supplements.
- Telomeres (which extend life) appear to be extended by Vitamin D - March 2015
- Telomere 254 items in VitaminDWiki as of July 2018
- Genetics category listing has
277 items along with related searches
- Telomeres improved when obese blacks took 2000 IU of vitamin D daily – Oct 2011
- Vitamin D extends lifespan about 60 percent (for worms in a lab) – Oct 2016
- 60 percent chance of longer white blood cell (leukocyte) telomere if have lots of vitamin D – May 2013
Items in both categories Genetics and Mortality are listed here:
Telomeres in boys were 2.5% longer if 9 ng higher vitamin D – July 2018
- Vitamin D appears to keep telomeres long (longer life) – Jan 2021
- Live longer if have more than 40 ng of Vitamin D (gene analysis of 10,500 people) – Jan 2019
- Telomeres in boys were 2.5% longer if 9 ng higher vitamin D – July 2018
- 5.8 X more likely to die in 15 year followup if low vitamin D and poor methylation – July 2018
- Increased mortality associated with low vitamin D genes – Nov 2014
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