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An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022

Journals Nutrients Volume 14 Issue 11 10.3390/nu14112353
by Milosz Caban andUrszula Lewandowska *ORCID
Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Kosciuszki 4, 90-419 Lodz, Poland

PDF Table of Contents


Ocular gene problems

The global prevalence of eye diseases continues to grow, bringing with it a reduction in the activity levels and quality of life of patients, and partial or complete blindness if left untreated. As such, there is considerable interest in identifying more effective therapeutic options and preventive agents. One such agent is vitamin D, known to have a range of anti-cancer, anti-angiogenic, anti-inflammatory and anti-oxidative properties, and whose deficiency is linked to the pathogenesis of a range of cardiovascular, cancer, and inflammatory diseases. This review presents the current stage of knowledge concerning the link between vitamin D and its receptor and the occurrence of eye disease, as well as the influence of analogues of calcitriol, an active metabolite of vitamin D. Generally, patients affected by various ocular disorders have vitamin D deficiency. In addition, previous findings suggest that vitamin D modulates the course of eye diseases and may serve as a marker, and that its supplementation could mitigate some disorders. However, as these studies have some limitations, we recommend further randomized trials to clarify the link between vitamin D and its activity with eye disease.
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VitaminDWiki - Genetics category contains

332 articles in the Genetics category

see also

Vitamin D blood test misses a lot
in Visio for 2023

  • Vitamin D from coming from tissues (vs blood) was speculated to be 50% in 2014, and by 2017 was speculated to be 90%
  • Note: Good blood test results (> 40 ng) does not mean that a good amount of Vitamin D actually gets to cells
  • A Vitamin D test in cells rather than blood was feasible (2017 personal communication)   Commercially available 2019
    • However, test results would vary in each tissue due to multiple genes
  • Good clues that Vitamin D is being restricted from getting to the cells
    1) A vitamin D-related health problem runs in the family

    especially if it is one of 51+ diseases related to Vitamin D Receptor

+2) Slightly increasing Vitamin D shows benefits (even if conventional Vitamin D test shows an increase) +3) DNA and VDR tests - 120 to 200 dollars $100 to $250 +4) PTH bottoms out ( shows that parathyroid cells are getting Vitamin d)

   Genes are good, have enough Magnesium, etc.

+4) Back Pain

   probably want at least 2 clues before taking adding vitamin D, Omega-3, Magnesium, Resveratrol, etc

      • The founder of VitaminDWiki took action with clues #3&4

VitaminDWiki - Vision category contains

Vision problems having many studies on VitaminDWiki

103 items in Vision category

VitaminDWiki - 8 studies in both categories Vision and Vitamin D Receptor

This list is automatically updated

VitaminDWiki - 6 studies in both categories Vision and Genetics

This list is automatically updated

VitaminDWiki - 3 studies in both categories Vision and CYP27B1

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Created by admin. Last Modification: Sunday July 24, 2022 01:34:23 GMT-0000 by admin. (Version 5)

Attached files

ID Name Comment Uploaded Size Downloads
18172 Ocular genes.jpg admin 24 Jul, 2022 43.28 Kb 245
18171 ToC Ocular.jpg admin 24 Jul, 2022 44.84 Kb 287
18170 D VDR Ocular.pdf admin 24 Jul, 2022 847.46 Kb 254