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An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022

Journals Nutrients Volume 14 Issue 11 10.3390/nu14112353
by Milosz Caban andUrszula Lewandowska *ORCID
Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Kosciuszki 4, 90-419 Lodz, Poland

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Ocular gene problems

The global prevalence of eye diseases continues to grow, bringing with it a reduction in the activity levels and quality of life of patients, and partial or complete blindness if left untreated. As such, there is considerable interest in identifying more effective therapeutic options and preventive agents. One such agent is vitamin D, known to have a range of anti-cancer, anti-angiogenic, anti-inflammatory and anti-oxidative properties, and whose deficiency is linked to the pathogenesis of a range of cardiovascular, cancer, and inflammatory diseases. This review presents the current stage of knowledge concerning the link between vitamin D and its receptor and the occurrence of eye disease, as well as the influence of analogues of calcitriol, an active metabolite of vitamin D. Generally, patients affected by various ocular disorders have vitamin D deficiency. In addition, previous findings suggest that vitamin D modulates the course of eye diseases and may serve as a marker, and that its supplementation could mitigate some disorders. However, as these studies have some limitations, we recommend further randomized trials to clarify the link between vitamin D and its activity with eye disease.
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VitaminDWiki - Genetics category contains

313 articles in the Genetics category

see also

Vitamin D blood test misses a lot
Blood Test Misses a lot (VDW 3439)

  • Vitamin D from coming from tissues (vs blood) was speculated to be 50% in 2014, and by 2017 was speculated to be 90%
  • Note: Good blood test results (> 40 ng) does not mean that a good amount of Vitamin D actually gets to cells
  • A Vitamin D test in cells rather than blood was feasible (2017 personal communication)
  •    Commercially available 2019
    • However, test results would vary in each tissue due to multiple genes
  • Good clues that Vitamin D is being restricted from getting to the cells
    1) A vitamin D-related health problem runs in the family
    2) Slightly increasing Vitamin D shows benefits (even if conventional Vitamin D test shows an increase)
    3) Vitamin D Receptor test (<$30) scores are difficult to understand in 2016
    • easier to understand the VDR 23andMe test results analyzed by FoundMyFitness in 2018

    4) Back Pain

VitaminDWiki - Vision category contains

89 Vision and Vitamin D items

VitaminDWiki - 7 studies in both categories Vision and Vitamin D Receptor

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VitaminDWiki - 6 studies in both categories Vision and Genetics

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VitaminDWiki - 3 studies in both categories Vision and CYP27B1

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Created by admin. Last Modification: Sunday July 24, 2022 01:34:23 GMT-0000 by admin. (Version 5)

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18172 Ocular genes.jpg admin 24 Jul, 2022 01:26 43.28 Kb 105
18171 ToC Ocular.jpg admin 24 Jul, 2022 01:25 44.84 Kb 130
18170 D VDR Ocular.pdf PDF 2022 admin 24 Jul, 2022 01:24 847.46 Kb 82