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Overview Asthma and Vitamin D

Did you know?
  • Asthma is one of the most prevalent chronic diseases worldwide
  • Most asthmatics have low Vitamin D levels
  • Adding Vitamin D decreases asthma: proven by many random controlled trials
          (More Asthma info below)

Learn how Vitamin D is essential for good health
  Watch a 5 minute video "Does Less Sun Mean more Disease?"
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If you have a disease associated with low Vit D take Vit D
Raising your Vit D levels will substantially prevent other low-Vit D health problems
Often your specific health problem will also be treated


See VitaminDWiki

The worse the bronchial asthma, the lower the vitamin D – Jan 2017
Related pages in VitaminDWiki

Meta-Analyses in VitaminDWiki


20 Recent studies in Breathing and Intervention categories (give vitamin D and see what happens) in VitaminDWiki:

20 Recent studies in Breathing and non-daily Intervention in VitaminDWiki:

Breathing and Vitamin D Binding Protein:

Items in both VitaminDWiki categories of Breathing and Magnesium:


Asthma worse if poor Vitamin D Receptor (not get to cells):

This list is NOT automatically updated


VitaminDWiki pages containing ASTHMA in title (127 pages as of July 2021)

Items found: 127
Title Modified
Poor response to Asthma inhaler if poor Vitamin D Receptor – Dec 2019 01 Jul, 2021
Overview Asthma and Vitamin D 01 Jul, 2021
Asthma and COPD in a few seniors greatly decreased by monthly 100,000 IU Vitamin D – RCT Feb 2021 28 Jun, 2021
Asthma treated by monthly 100,000 IU of Vitamin D if person had very low levels – RCT Feb 2021 06 Feb, 2021
Small vitamin D doses given during pregnancy do not reduce childhood asthma – meta-analysis Dec 2020 12 Dec, 2020
Childhood asthma problems eliminated for months by 600,000 IU of Vitamin D injection – June 2017 25 Jul, 2020
Those with Asthma or COPD had half the response to Vitamin D – March 2020 19 Mar, 2020
Antibiotics increased the risk of asthma by 47%, and allergies by 25% - Dec 2019 31 Dec, 2019
Asthma worse if lower Vitamin D – Dec 2019 10 Dec, 2019
Respiratory Disease exacerbations (Asthma, CF, COPD) may be treated by Vitamin D – July 2019 26 Nov, 2019
Asthma 3.7X higher risk of poor Vitamin D Receptor (teens in Taiwan in this case) – Nov 2019 07 Nov, 2019
Asthma is 20 percent more likely with a poor Vitamin D Receptor gene – meta-analysis Oct 2019 23 Oct, 2019
Asthma more closely associated with poor VDBP gene than with poor Vitamin D level – June 2014 15 Oct, 2019
Interactions of Asthma Vitamin D, Pollution and Obesity – July 2019 07 Jul, 2019
Babies 3.6X more likely to go to hospital for asthma if asthmatic mother had low vitamin D while pregnant – June 2019 22 Jun, 2019
Childhood Asthma risk greatly reduced if mothers were given 4,400 IU Vitamin D daily – RCT 2019 20 Jun, 2019
Asthma is poorly controlled if have 4 ng less Vitamin D – April 2019 25 May, 2019
Asthma supplementation by Vitamin D (any amount) reduced attacks by 25 percent – meta-analysis April 2019 11 May, 2019
Perhaps reduce asthma exacerbations with Vitamin D – April 2019 28 Apr, 2019
Not all Vitamin D levels follow the season – Asthma, Rhinitis, … – March 2019 31 Mar, 2019
Risk of infant Asthma cut in half if mother supplemented Vitamin D to get more than 30 ng – RCT Oct 2017 12 Mar, 2019
Childhood Asthma somewhat reduced by 2400 IU vitamin D late in pregnancy (néed more, earlier) March 2019 12 Mar, 2019
Asthma 3X more likely if have Multiple Sclerosis (both have low Vitamin D) – March 2019 08 Mar, 2019
Vitamin D every 14 weeks is not often enough (asthma in this case)– Feb 2019 21 Feb, 2019
Adult-onset asthma 2X more likely if low vitamin D and not hyperallergenic – May 2018 08 Jan, 2019
Vitamin D and allergy, asthma, atopic dermatitis, food allergy, autoimmune... 145 slides- 2017 30 Dec, 2018
Asthma in child 2.3 X more likely if both parents asthmatic (unless add Vitamin D) – VDAART Nov 2018 22 Nov, 2018
Asthma may be treated by Vitamin D if more than 40 ng for 12 months – Sept 2018 03 Nov, 2018
Asthma risk reduced by 67 percent with Vitamin D supplementation if level was initially low– meta-analysis Nov 2017 01 Aug, 2018
All asthma problems reduced after 1 year of Vitamin D – Nov 2017 10 Jul, 2018
Vitamin D and allergy, asthma, atopic dermatitis, food allergy, autoimmune, etc – slides May 2017 02 Jul, 2018
More lung capacity (bronchial asthma, FEV1) associated with higher vitamin D – July 2013 01 Jul, 2018
Asthma treated by daily 50,000 IU of Vitamin D – April 2018 24 Jun, 2018
Traffic pollution increases asthma unless supplement with Vitamin D (mice) June 2018 24 Jun, 2018
Both parents smoke – child’s vitamin D level was 30 percent lower and worse asthma – May 2018 26 Apr, 2018
Child Asthma increased 2.1 X by antibiotics, Child milk allergy increased 4.4 X by PPI – April 2018 02 Apr, 2018
Asthma 7 percent less likely for every 40 IU increase in (early) maternal diet – Feb 2018 23 Feb, 2018
Cesarean (associated with low Vitamin D) increased asthma, obesity, miscarriage and stillbirth – meta-analysis Jan 2018 26 Jan, 2018
Influenza reduced by 1.7 with 1200 IU D3, also reduced related asthma by 6X – RCT May 2010 10 Jan, 2018
Lots of sugar while pregnant doubles asthma risk – 2017 08 Dec, 2017
Decreased vitamin D in children taking asthma drugs - April 2010 18 Jul, 2017
Asthma attacks reduced in half if Vitamin D level higher than 42 nanograms – RCT May 2014 18 Jul, 2017
Acetaminophen (Tylenol) increases asthma 13 Jun, 2017
Reduction of infant asthma may require good vitamin D when lung development starts (4 weeks) – March 2017 02 May, 2017
Asthma reduced 60 percent with vitamin D supplementation – meta-analysis 2014, 2015 15 Jan, 2017
Asthma exacerbations in children decrease by 60 percent with vitamin D supplementation – meta-analysis – 2015 15 Jan, 2017
The worse the bronchial asthma, the lower the vitamin D – Jan 2017 11 Jan, 2017
Severity of adult asthma associated with less vitamin D – Feb 2013 08 Jan, 2017
Asthma not helped by less than 2,000 IU of vitamin D - meta-analysis Aug 2015 08 Jan, 2017
3 X increased chance of death if have asthma – study of 200,000 people over 10 years – Nov 2012 04 Jan, 2017

See asthma and Vitamin D on the web

5X less likely to be hospitalized for Asthma if adequate vitamin D
 Download the PDF from VitaminDWiki
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Children born with higher vitamin D less likly to get asthma later - May 2021

The correlation between neonatal vitamin D levels and the risk of childhood asthma attacks
Transl Pediatr. 2021 Apr;10(4):914-920. doi: 10.21037/tp-21-92.
Wenlin Li 1, Jin Zhou 2, Shen Liu 2, Kaihui Xing 1, Ling Yang 1, Lihua Zhong 1, Qiuli Chen 2, Wei Zhang 1
 Download the PDF from VitaminDWiki
Image

Background: To explore the correlation between neonatal vitamin D levels and the risk of asthma in children aged 3-9 years.

Methods: A total of 1,534 subjects were selected, and clinical and laboratory test data of all subjects were collected at birth, including 25-hydroxyvitamin D3 [25(OH)D3] levels, gender, season of birth, birth weight; whether delivery was premature, cesarean section, or primipara; and parental details including maternal age, ethnicity, level of education, history of smoking, and history of maternal or paternal asthma. The level of 25(OH)D3 was used as a continuous variable to analyze its correlation with the risk of asthma using the Cox proportional regression model. In addition, subjects were divided into four groups according to their 25(OH)D3 quartiles, and the first quantile group was used as a reference to analyze the risk of asthma in the other groups. Further subgroup analysis was conducted according to the patients' gender and birth season.

Results: Among the 1,534 subjects included, there were 107 cases in the asthma-affected group and 1,427 cases in the normal control group. Compared with the control group, the level of 25(OH)D3 in the asthma group was significantly lower (P=0.03), the mother's education level was lower (P=0.002), but the preterm birth rate, cesarean section rate, and parental asthma prevalence rate were significantly higher (all P<0.05). When the neonatal 25(OH)D3 was divided into quartiles to perform a categorical variable analysis, we found that compared with the first quantile (Q1, 0.0-25.1 mmol/L), the risk of asthma in Q4 was reduced by 50% (HR=0.50, 95% CI: 0.38-0.76). The second quantile group (Q2) and the third quantile group (Q3) showed no significant difference in the risk of disease compared with Q1 but showed a trend of decreasing risk as the quantile group increased (the trend P values were both <0.05). This correlation was still valid when a stratified analysis was made based on gender and birth season.

Conclusions: There is a significant correlation between a reduced vitamin D level in newborns and the subsequent risk of asthma in children aged 3-9 years. Moreover, the level of vitamin D is an independent risk factor for childhood asthma.


The worse the asthma in children, the lower their vitamin D level - Feb 2019

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Serum 25-hydroxy vitamin D in asthmatic children and its relation to disease severity
International Journal o fCommunity Medicine and Public Health, DOI: http://dx.doi.org/10.18203/2394-6040.ijcmph20185510
Ihab Hafez El Sawy, Passant Al-Said Moaz, Ghada Mohamed Farouk El Deriny, Mohamed Sami Abd El Moniem El Kholy

Background: Asthma is a chronic immunological disorder of the lungs. Vitamin D has several effects on the innate and adaptive immune systems. Little is known about vitamin D level and its impact on severity of asthma in children. This study aimed to determine vitamin D levels in asthmatics versus control children; studying the relation if any between these levels and asthma severity.

Methods: This cross-sectional study was conducted on 60 asthmatic children and 20 apparently healthy children as controls. Asthma patients were divided into 3 groups (mild, moderate, severe; 20 each). Asthma severity was based on GINA criteria. Vitamin D level was measured to all study group.

Results: The difference between the mean values of vitamin D level in control and asthmatic patients was statistically significant (p<0.001). This difference between control group and each asthma subgroup and between asthma subgroups versus each other were statistically significant being highest in control and lowest in patients with severe asthma (p<0.001). Differences in vitamin D status in control and all asthmatic patients were statistically significant (p<0.001). The difference between control group and each asthma subgroup according to vitamin D status were statistically significant (p<0.001). Concerning asthma subgroups the difference in vitamin D status between severe versus mild and moderate asthma were statistically significant (p<0.001), while between mild and moderate asthma it was not.

Conclusions: Significantly lower vitamin D level in asthmatic children compared to controls and a differential decrease in vitamin D levels in asthmatic children being lowest in severe asthma was confirmed.
 Download the PDF from VitaminDWiki


Asthma Drug Therapy (nothing about Vitamin D)

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Asthma is the most common health problem in children, inhalers not used properly - March 2019

Using an Asthma Inhaler Correctly NYT

  • "Asthma is the most common chronic disease of childhood, and using an asthma inhaler is often a first step toward medical autonomy for a child with asthma"
  • "Once or twice a day, children may take what are called controller therapies, most often inhaled corticosteroids which decrease chronic inflammation in the lungs and make exacerbations less likely. And then, when they feel symptoms coming on, or find themselves in a situation where symptoms seem likely, they use what are called rescue medications, bronchodilators which relax the smooth muscle so that air can move through those tubes."
  • "You have to take off the cap, shake the inhaler for three to five seconds and connect it to the spacer (a chamber between the inhaler and the patient’s mouth that holds the drug suspended and makes it easier to breathe it in). Then you are supposed to exhale completely, and put the mouthpiece or mask in or around your mouth correctly, forming a tight seal. Then you release the medication from the inhaler by pressing the canister down, breathe in slowly and deeply through the spacer (for spacers with a whistle, you do not want to hear the whistle), and hold your breath for 10 seconds. Finally, you exhale again — and then you wait a minute and repeat the process."
  • "Eighty-four percent of the patients did not wait the 30 seconds that the researchers felt was the absolute minimum time between inhalations. More than 50 percent waited less than 15 seconds."

Asthma reduced by Diet, Magnesium, Vitamin D, Tumeric, Breathing Exercises, Pine Bark, Vit B6

8 Proven Ways To Relieve Asthma Naturally GreenMed Info Jan 2019

  • "Asthma affects about 300 million people worldwide.It is growing by 50 percent every decade and causes upwards of 180,000 deaths per year"
  • "In a study of 1,531 children in Manitoba, Canada, researchers found that the risk of developing asthma by the age of seven was cut in half when the first diphtheria, pertussis, tetanus (DPT) immunization was delayed by more than two months. Delaying all three doses of DPT vaccines cut asthma risk by 60 percent."

Factoids from The Body by Bill Bryson, 2019

  • The U.K.:30 percent of children have shown asthma symptoms.
    • The lowest rates are in China, Greece, Georgia, Romania, and Russia, with just 3 percent.
  • Pearce. “I have spent thirty years studying asthma, and the main thing I have achieved is to show that almost none of the things people think cause asthma actually do. They can provoke attacks if you have asthma already, but they don’t cause it. We have very little idea what the primary causes are. We can do nothing to prevent it.”
  • with some asthmatics if you put their feet in a bucket of ice water, they begin to wheeze immediately. Now, that can’t be due to inflammation, because it happens too fast.
  • Asthma is very different from other lung disorders in that it is normally present only some of the time.
  • Even when there are no symptoms present, other diseases will nearly always be evident in blood or sputum tests. In asthma, in some cases, the disease just vanishes.”
Overview Asthma and Vitamin D        
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ID Name Comment Uploaded Size Downloads
15615 Asthma.jpg admin 21 May, 2021 12:40 32.49 Kb 158
15614 childhood asthma attacks.pdf PDF 2021 admin 21 May, 2021 12:40 254.20 Kb 19
15048 There’s No ‘One Size Fits All’ Treatment for Asthma - The New York Times.pdf admin 15 Feb, 2021 11:59 114.33 Kb 76
15047 Asthma guidelines.pdf PDF 2021 admin 15 Feb, 2021 11:48 1.21 Mb 122
11142 Asthma Feb 2019.jpg admin 04 Jan, 2019 02:34 31.14 Kb 3821
11141 Asthma.pdf PDF 2019 admin 04 Jan, 2019 02:30 373.00 Kb 603
10990 Asthma Drug Therapy.jpg admin 06 Dec, 2018 12:57 108.66 Kb 4803
9778 Asthma 2018.pdf PDF 2018 admin 26 Apr, 2018 20:27 336.88 Kb 802
9777 MEF25 percent.jpg admin 26 Apr, 2018 20:27 16.03 Kb 4674
3277 Astham types.jpg admin 15 Nov, 2013 12:24 96.71 Kb 3757
3003 Asthma Sept 2013.jpg admin 15 Sep, 2013 12:40 47.55 Kb 17938
3002 Asthma Sept 2013.pdf PDF 2013 admin 15 Sep, 2013 12:40 237.74 Kb 2375
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