Toggle Health Problems and D

Premature ejaculation associated with low vitamin D – 2018, 2019

There are 2 studies on this page

Serum vitamin D level may be a novel potential risk factor for premature ejaculation: a comparative study - Aug 2018

International Urology and Nephrology, pp 1–6 https://doi.org/10.1007/s11255-018-1975-x
Alaa Mohamed Abd El aalSameh Fayek GamalEl DinLaila Ahmed Rashed Abd El Rahman Bakry Tawfik Mohammed Said El Sheemy mohammedshemy at yahoo.com


36 ng premature vs 60 ng for "mature"
Conclusion: Need > 51 ng avoid premature ejaculation

Fertility and Sperm category contains the following summary

140 items in Fertility or Sperm in VitaminDWiki

See also:
Overview Women and Vitamin D
Overview Pregnancy and vitamin D    Fertility and Vitamin D – several articles
Ensure a healthy pregnancy and baby - take Vitamin D before conception
IVF OR "IN VITRO FERTILIZATION" etc. in 18 VitaminDWiki titles

Personal note by Henry Lahore, founder of VitaminDWiki - Aug 2018

I have always lived in Western Washington, which has the most clouds in the US and had previously suffered from

all of which are associated with low vitamin D,
   some of which are also associated with low Magnesium, Boron, Silica, Exercise
They have all gone away after my getting a good level of vitamin D
Also, I now have more muscle (age 72) than anytime previously in my life

See also web - various supplements to reduce Premature Ejaculation

To compare serum level of vitamin D [25(OH)D] in patients with life-long premature ejaculation (LPE) versus healthy controls.

Healthy married potent males were recruited from February 2017 to January 2018. Group A included 40 patients suffering from LPE who were compared versus 40 healthy controls (Group B ). Participants suffering from hormonal disorders, obesity, neurological, psychological, or chronic diseases or taking medications that may affect ejaculatory function, serum level of vitamin D, or the accuracy of intra-vaginal ejaculation latency time (IELT) were excluded. LPE was self-reported by the patients with subsequent feelings of frustration and measured by premature ejaculation diagnostic tool (PEDT) and IELT using stopwatch handled by their partners. 25(OH)D was measured by obtaining 2 ml of venous blood. Statistical analysis was performed using Student t, Mann–Whitney, Chi square tests, logistic regression analysis, and Spearman correlation.

Sixteen (20%) participants had vitamin D insufficiency/deficiency. All of them were in PE group. 25(OH)D correlated significantly with IELT (r2 = 0.349; p < 0.001) and PEDT (r2 = 0.425; p < 0.001). There was no statistically significant difference in age (p = 0.341), BMI (p = 1) or IIEF-5 (p = 0.408) in both groups. 25(OH)D was significantly lower in patients than controls (35.75 vs. 58.92 ng/ml, p < 0.001). ROC analysis revealed that the best cut-off value of 25(OH)D to detect patients suffering from LPE was 50.65 ng/ml with a sensitivity and specificity of 85% for both. 25(OH)D remained a significant risk factor for LPE in the logistic regression analysis (p < 0.001).

ConclusionsL The current study showed that vitamin D has significant association with LPE and correlates significantly with IELT and PEDT.

Low serum vitamin D is associated with an increased likelihood of acquired premature ejaculation - May 2019

Int Braz J Urol. 2019 May-Jun;45(3):621-628. doi: 10.1590/S1677-5538.IBJU.2018.0887.
Canat L1, Degirmentepe RB1, Atalay HA1, Çakir SS1, Alkan I1, Çulha MG1, Ozbir S1, Canat M2.
 Download the PDF from VitaminDWiki

PURPOSE: To investigate the relationship between 25-hydroxyvitamin D (25 (OH) D) levels and acquired premature ejaculation (PE).

A total of 97 patients with acquired PE and 64 healthy men as a control group selected from volunteers without PE attending our Andrology Outpatient Clinic between November 2016 and April 2017 were included the study. All patients were considered to have acquired PE if they fulfilled the criteria of the second Ad Hoc International Society for Sexual Medicine Committee. Premature ejaculation diagnostic tool questionnaires were used to assessment of PE and all participants were instructed to record intravaginal ejaculatory latency time. Vitamin D levels were evaluated in all participants using high performance liquid chromatography method included in the study.

Compared to men without PE, the patients with acquired PE had significantly lower 25 (OH) D levels (12.0 ± 4.5 ng/mL vs. 18.2 ± 7.4 ng/mL, p < 0.001). In the logistic regression analysis, 25 (OH) D was found to be an independent risk factor for acquired PE, with estimated odds ratios (95% CI) of 0.639 (0.460-0.887, p = 0.007) and the area under curve of the ROC curve of 25 (OH) D diagnosing acquired PE was 0.770 (95% CI: 0.695 to 0.844, p < 0.001). The best cut-off value was 16 ng/mL with a sensitivity of 60.9%, specificity of 83.5%, PPV of 70.9%, and NPV of 76.4% to indicate acquired PE.

This study demonstrates that lower vitamin D levels are associated with the acquired PE. The result of our study showed that the role of serum vitamin D levels should be investigate in the etiology of acquired PE. Perhaps supplementation of vitamin D in men with acquired PE will ameliorate the sexual health of these patients.

Title was revised July 2019 caused the visitor count to reset.
There have actually been 19778 visitors to this page since it was originally made

Attached files

ID Name Comment Uploaded Size Downloads
12404 premature ejaculation May 2019.pdf admin 30 Jul, 2019 787.63 Kb 1042