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More lung capacity (bronchial asthma, FEV1) associated with higher vitamin D – July 2013

Vitamin D and phenotypes of bronchial asthma

Egyptian Journal of Chest Diseases and Tuberculosis. Available online 5 July 2013
R. Eman Shebl a, emanshebl3000 at yahoo.com
Samah M. Shehata a,
Maha Elgabry a,
Salah A.I. Ali b,
Hanaa H. Elsaid b
a Department of Chest Diseases, Faculty of Medicine, Zagazig University, Egypt
b Department of Clinical Pathology, Faculty of Medicine, Zagazig University, Egypt

Background
Many studies have suggested the role of vitamin D deficiency in both T-helper1 and T-helper2 diseases. The existence of associations of vitamin D with asthma and allergy remains uncertain. While some suggest that vitamin D may be protective, others suggest that vitamin D supplementation may increase the risk of allergy.

Aim of the work
The aim of the study was to evaluate the state of vitamin D in asthmatic patients and its potential relationship with asthma phenotypes.

Patients and methods
This study was conducted on 66 nonsmoker asthmatic patients and 30 healthy controls. Serum 25-hydroxy vitamin D3 levels were determined and compared between the two groups.
The relationship between serum vitamin D levels and asthma phenotypes were examined.

Results
Vitamin D level was significantly lower in asthmatic patients than in control group, in asthmatic patients, vitamin D levels had a significant positive correlation with FEV1% predicted and a significant negative correlation with body mass index, the number of atopic patients was significantly higher in bronchial asthma patients with vitamin D insufficiency than those with sufficient vitamin D.

Conclusion
Vitamin D deficiency was highly prevalent in asthmatic patients and it was associated with atopy and asthma severity.

Volume of breath exhaled in 1 second vs. vitamin D

Image


PDF is attached at the bottom of this page

See also VitaminDWiki

Attached files

ID Name Comment Uploaded Size Downloads
2760 Volume vs vitamin D.jpg admin 09 Jul, 2013 15:41 20.86 Kb 1000
2759 asthma.pdf PDF 2013 admin 09 Jul, 2013 15:40 481.26 Kb 1027
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