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Reasons why some Respiratory Allergy studies find that Vitamin D does not help much – June 2020

The Role of Vitamin D in Respiratory Allergies Prevention. Why the Effect Is So Difficult to Disentangle?

Nutrients. 2020 Jun 17;12(6):E1801. doi: 10.3390/nu12061801.
Hanna Sikorska-Szaflik 1, Barbara Sozańska 1

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From the PDF

Study methodology
•dose and formulation of supplemented vitamin D
•duration and time of intervention (winter/summer)
•different laboratory methods to check serum vitamin D levels
•varied approach in defining outcomes (making a diagnose of allergic diseases)
Population included
•age of exposure (fetuses/children/adults)
•pregnancy
•comorbidities
•undertaken treatment
Individual Susceptibility
•skin pigmentation
•time spent outdoors
•family history
•lifestyle factors (smoking)


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 Download the PDF from VitaminDWiki

Asthma and allergic rhinitis are the most common chronic childhood diseases with an increasing prevalence worldwide. There is an urgent need to look for methods of preventing allergic diseases from an early age. The relationship between vitamin D status and allergic diseases has been discussed in several studies recently. 25-hydroxyvitamin D (25(OH)D) is suggested to affect the development and/or severity of asthma and allergic rhinitis. Observational studies have seemed to confirm that vitamin D deficiency may contribute to an increase in allergy and asthma. Following interventional studies, however, have yielded ambiguous results. In this review, we describe recent findings regarding 25(OH)D impact on allergic diseases and provide a systematic analysis of the causes of great variability of the achieved results in different studies.


Created by admin. Last Modification: Sunday June 21, 2020 15:04:31 GMT-0000 by admin. (Version 5)

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ID Name Comment Uploaded Size Downloads
13940 Respiratory Allergies - Difficult to Disentangle.pdf PDF 2020 admin 21 Jun, 2020 13:24 686.05 Kb 8
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