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Vitamin D supplementation guidelines (adults – 50,000 IU per week) – Feb 2017

The Journal of steroid biochemistry and molecular biology · Feb 2017, DOI: 10.1016/j.jsbmb.2017.01.021
Pawel Pludowski, Michael F. Holick, William B., Grant, Jerzy Konstantynowicz, Mario R. Mascarenhas, Afrozul Haq, Vladyslav Povoroznyuk, Nataliya Balatska, Ana Paula Barbosa, Tatiana Karonova, Ema Rudenka, Waldemar, Misiorowski, Irina Zakharova, Alena Rudenka, Jacek Łukaszkiewicz, Ewa Marcinowska-Suchowierska, Natalia Łaszcz, Pawel Abramowicz, Harjit P. Bhattoa, Sunil J. Wimalawansa

Neonates < 1 month 1,000 IU25 mcg
Infants 1 - 12 months 2000-3000 IU50-75 mcg/
Children and adolescents 1 - 18 years3000-5000 IU75–125 mcg
Adults and the elderly 18+ years7000–10,000 IU
50,000 IU/week
175–250 mcg

 Download the SciHub PDF (accepted manuscript) via VitaminDWiki

Clips from PDF

  • “It is generally accepted that a serum 25(OH)D concentration of up to 100 ng/mL is safe for children and adults, with the exception of those who have a hypersensitivity to vitamin D.”
  • ““The Endocrine Society guidelines concluded that vitamin D toxicity is not only extremely rare, but 25(OH)D concentration of at least 150 ng/mL is required before there would be evidence of vitamin D toxicity.”
  • “25(OH)D concentrations of 30-50 ng/mL (75-125 nmol/L) are beneficial for overall health

This study does not address

  1. Increased vitamin D needs for Overweight/Obese, Pregnant, Premies, Sick, etc.
  2. People with genes (5 kinds) which restrict blood vitamin D from getting to the cells
  3. Cofactor adjustments when Vitamin D level is > 30 ng for > 1 year
  4. Loading dose - to quickly restore vitamin D levels
  5. Other types of vitamin D - for those with poor guts, vegitarians, . .
  6. Other forms of vitamin D: topical, injection, inhaled, Calcitriol, etc.
  7. Hypersensitivity is often due to low levels of Magnesium
  8. When to take the vitamin D (with largest meal of the day)

Getting Vitamin D into your body has the following chart


See also VitaminDWiki

see wikipage http://www.vitamindwiki.com/tiki-index.php?page_id=3057

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Vitamin D supplementation guidelines (adults – 50,000 IU per week) – Feb 2017        
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