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50,000 IU of Vitamin D every 2 weeks reduced gestational diabetes – RCT Feb 2015


Supplementation of Vitamin D in Pregnancy and its Correlation with feto-maternal outcome

Clinical Endocrinology, DOI: 10.1111/cen.12751
Aanchal Sablok1,*, Aruna Batra1, Karishma Thariani1, Achla Batra1, Rekha Bharti1, Abha Rani Aggarwal2, BC Kabi3 and Harish Chellani4
1 Department of Obstetrics and Gynaecology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India
2 National Institute of Medical Statistics, All India Institute of Medical Sciences, New Delhi, India
3 Department of Biochemistry, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India
4 Department of Paediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India

  • Corresponding author: Dr. Aanchal Sablok, Senior Resident, Department of Obstetrics and Gynaecology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi. 110029, India. aanchalsablok54 at gmail.com

VitaminDWiki Summary
ControlIntervention
Vitamin D Level 18 ng 32 ng
Preterm labor
or Pre-eclampsia
or Gestational Diabetes
44 % 20 %
Birth weight 2.4 kg2.6 kg

 Download the PDF from VitaminDWiki

Context: Vitamin D deficiency is widely prevalent throughout the world. Pregnant women, neonates, and infants form the most vulnerable groups for vitamin D deficiency.

Objective: 1) To find the prevalence of vitamin D deficiency in pregnant women. 2) To evaluate the effect of supplementation with cholecalciferol in improving vitamin D levels in pregnant women and evaluate its correlation with feto-maternal outcome.

Design: Randomized control trial from the years 2010-2012.

Setting: Tertiary care center, Delhi, India.

Participants: 180 pregnant women. The study population was divided randomly into 2 groups; Group A: non-intervention (60 women) and Group B: intervention (120 women).

Intervention: The intervention group received supplementation of vitamin D in dosages depending upon 25(OH)-D levels.

Main Outcome Measures: Risk of maternal complications like Preterm labor, pre-eclampsia, and gestational diabetes associated with Vitamin D deficiency and risk of Low birth weight and poor APGAR score in infants of mothers with Vitamin D deficiency.

Results: Adjusted serum 25(OH)-D concentration was lower in group A as compared to group B (mean 46.11 ± 74.21 nmol/L vs 80 ± 51.53 nmol/L). 44% of patients in group A and 20.3% of patients in group B developed Pre-term labor/Pre-eclampsia/Gestational Diabetes. New-borns of mothers in group A had lower cord blood levels of 25(OH)-D levels as compared to group B (mean 43.11 ± 81.32 nmol/L vs 56.8 ± 47.52 nmol/L). They also had lower birth weight of mean 2.4 ± 0.38 kg as compared to group B 2.6 ± 0.33 kg.

Conclusions: Vitamin D supplementation reduces the risk of maternal comorbidities and helps improve neonatal outcomes.


See also VitaminDWiki

Healthy pregnancies need lots of vitamin D the following summary

Problem
ReducesEvidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial


VitaminDWiki with GESTATIONAL DIABETES in the title (36 as of July 2022)

This list is automatically updated

Items found: 38
Title Modified
Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT June 2014 17 Jul, 2023
50,000 IU of Vitamin D every 2 weeks reduced gestational diabetes – RCT Feb 2015 12 Jul, 2023
Poor placental Vitamin D genes associated with gestational diabetes and preeclampsia - April 2023 01 May, 2023
Gestational Diabetes Mellitus 10X more-likely if low vitamin D in first trimester – July 2022 07 Aug, 2022
Gestational Diabetes 2.1 X more likely if less than 30 ng of Vitamin D - July 2022 14 Jul, 2022
Gestational diabetes risk reduced 1.5X by Vitamin D – meta-analysis March 2021 14 Jul, 2022
Vitamin D reduces preeclampsia, gestational diabetes and hypertension - 38th meta-analysis Dec 2021 31 May, 2022
Gestational Diabetes – increased risk if poor Vitamin D Receptor – 2 Meta-Analyses 2021 14 Dec, 2021
300,000 IU injection loading dose of vitamin D3 stopped gestational diabetes in RCT – Oct 2011 25 Jul, 2020
Vitamin D cuts pregnancy risks in half – low birth weight, preeclampsia, gestational diabetes – Cochrane July 2019 12 Sep, 2019
Gestational Diabetes 2.4X more likely if poor Vitamin D Receptor (region in China) – June 2019 24 Jun, 2019
Vitamin D food fortification during pregnancy reduced gestational diabetes in daughters by 13 percent – Nov 2018 14 Jun, 2019
Gestational Diabetes 3 X more likely if poor Vitamin D receptor (Turkey) – May 2019 18 May, 2019
Gestational diabetes 60 percent more likely below 20 ng of vitamin D – meta-analysis Feb 2012 23 Mar, 2019
Vitamin D treats Gestational Diabetes, decreases hospitalization and newborn complications – meta-analysis March 2019 23 Mar, 2019
Gestational Diabetes 39 percent more likely if insufficient Vitamin D – Meta-analysis March 2018 17 Mar, 2018
Gestational Diabetes Mellitus 1.5X more likely if low vitamin D – meta-analysis Oct 2015 07 Feb, 2018
Gestational diabetes treated by Vitamin D plus Omega-3 – RCT Feb 2017 02 Jan, 2018
Gestational Diabetes increasing, especially in dark skinned women (low vitamin D) - 2007 30 Dec, 2017
Gestational Diabetes 1.9 X more likely if low vitamin D – review Dec 2017 15 Dec, 2017
Congenital Heart Disease is associated with gestational diabetes in first trimester (need Vitamin D and Omega-3 early) Dec 2017 15 Dec, 2017
Vitamin D Receptor is associated with preeclampsia, gestational diabetes and preterm birth – Nov 2017 10 Nov, 2017
Gestational Diabetes Mellitus associated with 4 Vitamin D genes – Oct 2015 09 Nov, 2017
Gestational diabetes 30 percent less likely if consumed more than 400 IU of vitamin D daily – Oct 2017 04 Oct, 2017
Low vitamin D plus gestational diabetes resulted in increased ICU use, SGA – Oct 2016 07 Jun, 2017
Gestational Diabetes 3.7 X more likely if smoke and have low vitamin D (no surprise) – Feb 2016 04 Jan, 2017
Gestational Diabetes reduce 3 times by 5,000 IU of Vitamin D – RCT Jan 2016 10 Dec, 2016
Gestational Diabetes treated with 50,000 IU every two weeks – RCT Sept 2016 03 Sep, 2016
Infant much healthier if Gestational Diabetic mother got 2 doses of vitamin D – RCT Nov 2014 09 Apr, 2016
Gestational Diabetes helped by Vitamin D and Calcium (also less C-section and LGA) – RCT Jan 2016 16 Jan, 2016
Gestational diabetes – Vitamin D and Calcium provided huge benefits – RCT March 2015 13 Jan, 2016
Gestational diabetes reduced by just two 50,000 IU doses of vitamin D – RCT Nov 2014 02 Oct, 2015
Increased Gestational Diabetes and poorer infant health associated with low vitamin D – June 2015 01 Jul, 2015
Gestational Diabetes in 10 percent of pregnancies, vitamin D probably helps – Jan 2014 14 Apr, 2015
Gestational Diabetes reduced 40 percent by 5,000 IU of vitamin D – RCT April 2014 02 Mar, 2015
Gestational Diabetes mostly treated with just 2 doses of 50,000 IU of vitamin D – RCT Dec 2013 26 Jun, 2014
Will 1600 IU vitamin D prevent gestational diabetes – no, not enough, July 2013 31 Aug, 2013
Gestational diabetes 2.2X more likely below 10 ng of vitamin D – June 2012 15 Nov, 2012

229+ VitaminDwiki pages have 50,000 or 60,000 IU in their title

Note: India uses 60,000 IU capsules

Items found: 241
Title Modified
Depression in seniors greatly reduced by Vitamin D (e.g. 50,000 IU) – meta-analysis June 2023 06 Nov, 2023
Consensus: 60,000 IU of Vitamin D weekly for 2-6 months can fight COVID, etc, – India April 2022 13 Oct, 2023
50,000 IU of Vitamin D - many studies 12 Oct, 2023
Fibromyalgia pain, fatigue, etc. reduced by 50,000 IU of Vitamin D for 12 weeks – Sept 2023 04 Oct, 2023
Hospital costs higher for those with low vitamin D (7,000 Germans in their 50's) – Nov 2017 03 Oct, 2023
Muscles improved in women with 50,000 IU vitamin D weekly (8 weeks) plus daily Magnesium – RCT Sept 2020 16 Sep, 2023
Venous ulcers healed 4X faster with weekly 50,000 IU vitamin D – RCT Oct 2012 08 Sep, 2023
Senior cognition improved in 4 ways by Vitamin D (50,000 IU weekly for 8 weeks) – Sept 2023 06 Sep, 2023
Chronic Periodontitis reduced by Vitamin D (60,000 IU weekly for 8 weeks) – RCT July 2023 01 Sep, 2023
Muscle pain in obese women reduced by aerobic exercise plus 50,000 IU Vitamin D - RCT May 2021 27 Aug, 2023
Type 2 Diabetes treated by Vitamin D (often 50,000 IU weekly) – meta-analysis July 2023 21 Aug, 2023
IBS reduced by 50,000 IU of Vitamin D (weekly or bi-weekly) – Meta-analysis July 2023 16 Aug, 2023
Sleep greatly improved by 50,000 IU of vitamin D once every two weeks – RCT Sept 2018 07 Aug, 2023
Pain not reduced by 60,000 IU monthly vitamin D (need 50,000 IU weekly) – RCT Aug 2023 22 Jul, 2023
How often might 50,000 IU vitamin D be taken - results of clinical trials 18 Jul, 2023
Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT June 2014 17 Jul, 2023
Menstrual pain reduced by weekly 50,000 IU of Vitamin D – meta-analysis June 2023 15 Jul, 2023
Multiple Sclerosis fatigue reduced by weekly Vitamin D (50,000 IU) – June 2023 15 Jul, 2023
Cardiovascular events – need more than monthly 60,000 IU vitamin D to prevent other than infarction – June 2023 13 Jul, 2023
60,000 IU vitamin D weekly with daily Calcium was safe but not enough in the winter – 2012 13 Jul, 2023
50,000 IU of Vitamin D every 2 weeks reduced gestational diabetes – RCT Feb 2015 12 Jul, 2023
Cognition improved in 5 ways after Vitamin D increased to 32 ng (50,000 weekly) – June 2023 03 Jul, 2023
Multiple Sclerosis treated equally by UVB and weekly 50,000 IU of Vitamin D – RCT July 2023 18 Jun, 2023
Mild Obstructive Sleep Apnea decreased by 50,000 IU weekly vitamin D – June 2021 20 May, 2023
Chronic tonsillitis virtually eliminated in children by Vitamin D (50,000 IU weekly) – RCT May 2023 20 May, 2023
Breast Cancer trial using 50,000 IU Vitamin D weekly cancelled (no funding) 18 Apr, 2023
Breast Cancer trial using 50,000 IU Vitamin D weekly cancelled (no funding) 18 Apr, 2023
Health can be greatly improved by weekly 50,000 IU of Vitamin D - video and charts - March 2023 02 Apr, 2023
Health can be greatly improved by weekly 50,000 IU of Vitamin D - video and transcript - March 2023 01 Apr, 2023
Urinary Incontinence reduced by 50,000 IU of vitamin D weekly (details behind paywall) – RCT Feb 2023 24 Feb, 2023
50,000 IU and other high dose vitamin studies 15 Jan, 2023
Lupus: 60,000 IU Vitamin D monthly got to only 34 ng, not enough to help – RCT Jan 2023 04 Jan, 2023
Can get 50,000 IU Vitamin D anywhere on the globe 21 Dec, 2022
50,000 IU Vitamin D weekly is often recommended 30 Nov, 2022
COVID US deaths: 116,000 fewer if everyone had been taking 50,000 IU Vitamin D – Campbell transcript Nov 2022 21 Nov, 2022
50,000 weekly increased vitamin D levels in breast cancer patients – Mar 2011 06 Nov, 2022
Diabetes prevented by 50,000 IU vitamin D monthly (Iran) – Jan 2022 03 Nov, 2022
Immune systems of overweight black women improved by monthly 60,000 IU Vitamin D – RCT Oct 2022 14 Oct, 2022
Number needed to vaccinate to prevent 1 Omicron death: 30,000 for age 60-70 - Sept 2022 29 Sep, 2022
60,000 IU of vitamin D monthly is healthy and safe – RCT Aug 2022 19 Aug, 2022
10,000 IU Vitamin D raised basketball player levels (more than 50 ng need to improve performance) – June 2022 01 Aug, 2022
Long-term Psoriasis cured by 30,000 to 60,000 IU of Vitamin D daily (pictures and video) – early 2022 22 Jul, 2022
COVID etc. prevented and treated with 50,000 IU Vitamin D capsules - July 2022 22 Jul, 2022
50,000 IU of Vitamin D weekly for 6 months after cardiac failure helps – RCT May 2022 11 Jun, 2022
50,000 IU capsules of Vitamin D can be obtained everywhere - Jan 2022 26 Jan, 2022
Poor odor detection if low Vitamin D, better after 50,000 IU weekly - July 2021 23 Jan, 2022
Take 50,000 IU of Vitamin D weekly for 2 months, then get a test - Dec 2021 20 Jan, 2022
Resistance training can be aided by Vitamin D, 50,000 IU monthly is not often enough – RCT Dec 2021 11 Jan, 2022
Mortality reduction needs more than monthly 60,000 IU of Vitamin D - RCT Jan 2022 11 Jan, 2022
Several smoking problems treated by Vitamin D (bi-weekly, 50,000 IU) - RCT Dec 2021 29 Dec, 2021
Sleeps disorders nicely treated by Vitamin D (50,000 IU twice a month) – RCT May 2017 27 Oct, 2021
50,000 IU Vitamin D weekly was the most popular for Breast Cancer - May 2020 30 Aug, 2021
Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021 19 Aug, 2021
Falls not decreased by 60,000 IU Vitamin D monthly (not a news item) – RCT Aug 2021 02 Aug, 2021
Vitamin D for infections and COVID (50,000 IU weekly for 3 months) – July 2021 02 Aug, 2021
Vitamin D home tester wanted – 50, 000 dollar prize offered by Nestlé – Feb 2019 16 Jul, 2021
Yet another study confirms Depression is treated by weekly Vitamin D (50,000 IU)– RCT Dec 2019 09 Jul, 2021
Cognitive function of adult women improved in 3 months of 50,000 IU weekly Vitamin D – Jan 2019 09 Jul, 2021
Melanoma not treated by small doses of vitamin D (100,000 IU every 50 days) – RCT June 2021 30 Jun, 2021
Immune systems helped by 50,000 IU of vitamin D (weekly for 3 months) – May 2021 03 Jun, 2021
Peripheral diabetic neuropathy helped by weekly 50,000 IU vitamin D – Jan 2019 25 May, 2021
COVID-19 inflammation extinguished by 60,000 IU of vitamin D nanoemulsion daily for a week – RCT May 2021 22 May, 2021
54 genes significantly affected by Vitamin D (50,000 IU weekly for 12 weeks) – May 2021 12 May, 2021
Depression treated by 50K IU Vitamin D weekly (but not 1,000 IU daily) – meta-analysis Jan 2021 25 Apr, 2021
50,000 IU of Vitamin D once every 2 weeks achieved 40 ng in 3 months – RCT March 2021 24 Apr, 2021
Reduce COVID-19 risks with 50,000 IU Vitamin D doses 14 Mar, 2021
Stroke patients getting weekly 50,000 IU Vitamin D did better – trial March 2021 12 Mar, 2021
Ischaemic stroke – Vitamin D doubled survival (Injection followed by monthly 60,000 IU) – RCT Aug 2016 05 Mar, 2021
Vitamin D reduced COVID-19 inflammation (60,000 IU daily for 8 days) - RCT Feb 2021 24 Feb, 2021
Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021 23 Feb, 2021
Weekly 50,000 IU was the most succesful way to restore vitamin D levels (football) - Aug 2020 08 Feb, 2021
Endometriosis treated by Vitamin D (50,000 IU bi-weekly) – RCT Jan 2021 30 Jan, 2021
Bone density improved by monthly 50,000 IU of vitamin D for 6 months – RCT Jan 2021 19 Jan, 2021
Migraine headaches reduced with 50,000 IU vitamin D weekly – RCT July 2015 14 Jan, 2021
Take 50,000 IU of Vitamin D weekly before and after COVID-19 vaccination 27 Dec, 2020
Influenza prevented by 40 ng levels or treated with vitamin D hammer (50,000 IU) – June 2015 26 Dec, 2020
Trial: Can 50,000 IU of Vitamin D weekly help with Breast Cancer Chemotherapy - Early 2021 21 Dec, 2020
A call to action: Vitamin D for hip fracture (50,000 weekly for 8 weeks, then bi-weekly – Holick July 2020 11 Dec, 2020
50,000 IU vitamin D weekly to avoid Osteroporosis after Breast Cancer - May 2020 26 Nov, 2020
BPH (PSA) decreased by Vitamin D (50,000 IU bi-weekly) – RCT Nov 2020 21 Nov, 2020
60,000 IU dose of VItamin D (weekly, monthly) is popular in India 17 Nov, 2020
In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly – Dec 2024 14 Sep, 2020
Only 1 NCAA basketball player getting 10,000 IU vitamin D daily achieved 50 ng goal – Jan 2020 01 Sep, 2020
Sperm not improved enough by Vitamin D - 50,000 IU weekly for 8 weeks - RCT Aug 2020 27 Aug, 2020
Newborn Vitamin D - single 50,000 IU is better than daily – RCT Sept 2016 25 Jul, 2020
Weekly 50,000 IU of vitamin D is again found to be good – RCT May 2020 27 May, 2020
COVID-19 might be prevented in 2 months by 50,000 IU weekly – May 12, 2020 12 May, 2020
Reduce Coronavirus risk with Vitamin D (50,000 IU once a week) 27 Mar, 2020
IBS diarrhea treated by weekly 50,000 IU of Vitamin D – RCT March 2020 25 Mar, 2020
50,000 IU Vitamin D weekly provided enough benefit for combat sport athletes – March 2020 21 Mar, 2020
Response by obese to weekly 50,000 IU of Vitamin D – May 2018 12 Feb, 2020
Irritable Bowel Syndrome treated by weekly 50,000 IU Vitamin D – RCT Feb 2019 18 Jan, 2020
Hip surgery with multiple doses of 50,000 IU of vitamin D weekly both before and after – RCT 2023 16 Jan, 2020
Low Vitamin D symptoms, need 50-80 ng, he takes 5,000 IU – Matthews interview Dec 2019 29 Dec, 2019
Obese lost more weight on diet if added 50,000 IU of vitamin D weekly – many RCTs 25 Dec, 2019
Obese taking 50,000 IU of vitamin D weekly lost more weight (again) – RCT Dec 2019 25 Dec, 2019
General Anxiety Disorder treated by weekly Vitamin D (50,000 IU -Omega-3, Mg also help) – Sept 2019 09 Dec, 2019
Cystic Fibrosis not helped by 50,000 IU of Vitamin D taken twice a month – RCT Feb 2019 01 Nov, 2019
Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – 2016, 2017, 2018, 2019 19 Oct, 2019
PMS again significantly reduced by 50,000 IU of vitamin D (This time, every two weeks) – RCT Oct 2019 19 Oct, 2019
Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT Oct 2019 17 Oct, 2019
Long-term neck and back pains greatly reduced by 50,000 IU of Vitamin D – 4 cases – Sept 2019 14 Sep, 2019
Hashimoto's thyroiditis helped by weekly 50,000 IU of vitamin D – RCT May 2019 10 Sep, 2019
Preeclampsia 2.7 X less likely if 50,000 IU of Vitamin D every 2 weeks – meta-analysis Sept 2019 06 Sep, 2019
Severely Obese not helped much by 50,000 IU of vitamin D weekly for 8 weeks – RCT June 2019 21 Aug, 2019
Athletes helped by weekly 50,000 IU Vitamin D – RCT Aug 2019 10 Aug, 2019
Hay Fever treated by Vitamin D (50,000 IU weekly) – RCT July 2019 02 Aug, 2019
Vitamin D less costly if give 100,000 IU monthly (but 50,000 IU biweekly should save more money) – July 2019 16 Jul, 2019
Urgency Urinary Incontinence in senior black women decreased 40 percent by weekly 50,000 IU vitamin D – RCT Dec 2018 07 Jul, 2019
Diabetic inflammation reduced by Calcium and 50,000 IU of vitamin D in 8 weeks – RCT 2014 01 Jul, 2019
Type 2 Diabetes inflammation reduced by 50,000 IU of Vitamin D bi-weekly and resistance training – RCT – June 2019 01 Jul, 2019
Treating Vitamin D deficiency in senior women – such as 50,000 IU daily for 15 days then twice a month – Review April 2019 14 Jun, 2019
Methadone cognition improved by 50,000 IU of vitamin D every 2 weeks – RCT May 2019 13 Jun, 2019
Grip strength following wrist fracture increased by 50,000 IU Vitamin D monthly – May 2019 09 May, 2019
PMS in teens reduced 3X by 50,000 IU vitamin D weekly – Jan 2018 23 Mar, 2019
Schizophrenia reduced by biweekly 50,000 IU Vitamin D and probiotics – RCT Feb 2019 21 Feb, 2019
Poor Vitamin D binding had 30 percent less response to Vitamin D (50,000 IU weekly) – Feb 2019 04 Feb, 2019
Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018 12 Jan, 2019
Sleep improved with 50,000 IU Vitamin D every two weeks – RCT Oct 2018 20 Dec, 2018
Depression probably treated by bi-weekly 50,000 IU of vitamin D - RCT 2020 05 Dec, 2018
50,000 IU of vitamin D weekly following cardiac failure helps – RCT 2014 24 Nov, 2018
Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT Nov 2018 21 Nov, 2018
Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT Jan 2019 17 Nov, 2018
Diabetes treated if given enough vitamin D (example: 50,000 IU weekly) – review of RCT - Jan 2017 02 Nov, 2018
Depression in seniors treated by weekly 50,000 IU of vitamin D – RCT Sept 2018 15 Oct, 2018
Preterm birth cost for employers approximately 50,000 dollars – Oct 2017 28 Sep, 2018
50,000 IU of Vitamin D weekly for 9 weeks did not improve CVD – Aug 2018 28 Aug, 2018
Multiple Sclerosis and Vitamin D ~ 50,000 Facebook members in 13 languages – Jan 2017 23 Aug, 2018
Osteoporosis in men increased their risk of Dementia by 1.3 (60,000 Germans) – July 2018 21 Aug, 2018
Multiple Sclerosis treated by 50,000 IU Vitamin D bi-weekly plus Omega-3 – RCT July 2018 06 Jul, 2018
Asthma treated by daily 50,000 IU of Vitamin D – April 2018 24 Jun, 2018
Fibromyalgia pain substantially reduced by weekly Vitamin D (50,000 IU) – June 2018 23 Jun, 2018
Vitamin D - at least 4,000 IU to achieve 40-60 ng and reduce risk of early death – Holick June 2018 04 Jun, 2018
Pancreatic Cancer stabilized by a woman taking 50,000 IU of vitamin D daily - 2016 03 Jun, 2018
Pregnancies helped a lot by Vitamin D (injection then 50,000 IU monthly) – RCT May 2018 28 May, 2018
Concussion which caused unconsciousness increased risk of Parkinson's by 50 percent (300,000 military) - May 2018 07 May, 2018
Knee pain and depression reduced by monthly 50,000 IU vitamin D – RCT April 2018 21 Apr, 2018
50,000 IU vitamin D routinely given monthly in New Zealand senior homes since 2011– Dec 2016 07 Apr, 2018
IBS quality of life improved by vitamin D (50,000 IU every two weeks) – RCT May 2016 14 Mar, 2018
Pain not relieved by monthly 100,000 IU of vitamin D (need 50,000 IU weekly) – RCT Feb 2018 02 Mar, 2018
HbA1c levels (Diabetes) reduced by monthly 50,000 IU of vitamin D – Dec 2017 01 Mar, 2018
Common cause of dizziness (BPPV) treated by several doses of 50,000 IU of vitamin D – 2015, 2016 11 Feb, 2018
Common cause of dizziness (BPPV) reduced 5 X by several doses of 50,000 IU of vitamin D – 2015, 2016 11 Feb, 2018
Cystic Fibrosis got some benefit from 50,000 IU of vitamin D weekly (need gut-friendly form) – Feb 2018 03 Feb, 2018
Sleep disorders treated with 50,000 IU Vitamin D every 2 weeks – RCT May 2017 07 Dec, 2017
Hypertension not controlled by 26 ng of Vitamin D (50,000 IU bi-weekly A-A) – RCT Nov 2017 18 Nov, 2017
Vitamin D taken daily (4,000 IU) vs weekly (50,000 IU) – RCT 2019 23 Oct, 2017
Vitamin D supplementation for newborns – 400 IU daily vs 50,000 IU dose – RCT Sept 2016 21 Oct, 2017
Dry eye decreased with weekly 50,000 IU vitamin D injection for 8 weeks – Sept 2017 07 Sep, 2017
Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017 01 Sep, 2017
Sleep quality improved with 50,000 IU of vitamin D every two weeks – RCT May 2017 23 Aug, 2017
Preeclampsia reoccurred half as often if get 50,000 IU of Vitamin D every two weeks – Aug 2017 22 Aug, 2017
Vitamin D supplementation guidelines (adults – 50,000 IU per week) – Feb 2017 21 Aug, 2017
Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D – Jan 2017 27 Jul, 2017
Canadian grant funding lost for prescribing 50,000 IU of vitamin D – July 2017 23 Jul, 2017
Cervical lesions (precancerous, identified by pap smear) treated by bi-weekly 50,000 IU of vitamin D – RCT Feb 2017 22 Jul, 2017
Type 1 diabetes helped with 50,000 IU of vitamin D every two weeks – Nov 2014 20 Jul, 2017
Knee osteoarthritis treated with vitamin D, weekly 50,000 IU – May 2015 20 Jul, 2017
50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013 20 Jul, 2017
Preeclampsia recurrence reduced 2 X by 50,000 IU of vitamin D every two weeks – RCT July 2017 17 Jul, 2017
Chinese women in tropics needed 50,000 IU of Vitamin D monthly to keep above 30 ng – RCT May 2017 14 Jul, 2017
50,000 IU of vitamin D every two weeks – Jordan conclusion - RCT July 2017 08 Jul, 2017
Fertility marker (Anti-Müllerian Hormone) improved in a week by a single dose to 50,000 IU of vitamin D – RCT July 2017 08 Jul, 2017
Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – Nov 2016 27 Jun, 2017
Many benefits of 50,000 IU vitamin D every two weeks (methadone treatment) – RCT June 2017 21 Jun, 2017
Don’t take a PRESCRIPTION of 50,000 IU of vitamin D – June 2017 05 Jun, 2017
Vitamin D – 50,000 IU monthly is enough if near the equator and have normal weight – May 2017 25 Apr, 2017
50,000 IU of vitamin D weekly (D3 or D2) got two thirds of cystic fibrosis patients to 30 nanograms – RCT July 2015 22 Apr, 2017
Single dose (up to 60,000 IU) vitamin D raised levels in 87 percent of Cystic fibrosis patients – RCT March 2013 04 Apr, 2017
Prediabetes reduced by monthly 60,000 IU of vitamin D – RCT May 2015 15 Mar, 2017
50,000 IU vitamin D weekly is safe and effective for Primary Hyperparathyroidism – Jan 2013 23 Jan, 2017
Pulmonary hypertension reduced in some people with weekly 50,000 IU vitamin D for 3 months – 2016 16 Jan, 2017
Chronic Back Pain relieved by weekly 60,000 IU of vitamin D – Jan 2017 10 Jan, 2017
50,000 IU of vitamin D for 8 weeks of pregnancy raised most above 30 nanograms - RCT Jan 2017 28 Dec, 2016
Knee osteoarthritis pain reduced by 60,000 IU monthly vitamin D following loading dose – RCT Nov 2013 24 Dec, 2016
Juvenile Lupus fatigue reduced by vitamin D ( 50,000 IU weekly for 6 months) – RCT May 2015 24 Nov, 2016
Antibiotic use cut in half by elderly (over 70) after monthly 60,000 IU of vitamin D – RCT Dec 2013 06 Oct, 2016
Chikungunya virus arthritis pain reduced by weekly 60,000 IU vitamin D – Sept 2016 29 Sep, 2016
Gestational Diabetes treated with 50,000 IU every two weeks – RCT Sept 2016 03 Sep, 2016
Vitamin D trial – 60,000 IU monthly to reduce death and colon cancer – results due 2025 12 Aug, 2016
5,000 IU daily or 50,000 IU Vitamin D weekly repleted many dark skinned adolescents – RCT Dec 2015 06 Aug, 2016
Free Vitamin D in New Zealand to prevent falls in nursing homes (50,000 IU monthly) – June 2016 30 Jul, 2016
Non-alcoholic fatty liver disease (NAFLD) reduced somewhat by 50,000 IU vitamin D every 2 weeks – RCT Sept 2014 13 Jul, 2016
A group of 6,000 people have vitamin D levels higher than 50 ng – GrassrootsHealth 29 Jun, 2016
50,000 IU vitamin D daily in ICU greatly reduces number and cost of heart attacks – Nov 2015 24 Jun, 2016
Nursing home residents need Vitamin D 4,000 IU daily or 50,000 IU weekly – Jan 2016 25 May, 2016
Insulin resistance during pregnancy improved with 50,000 IU of vitamin D every 2 weeks – April 2013 23 May, 2016
Insulin resistance during pregnancy improved with 50,000 IU of vitamin D every 2 weeks – RCT April 2013 23 May, 2016
IBS quality of life improved by vitamin D (50,000 IU weekly) – RCT May 2016 17 May, 2016
Monthly 60,000 IU of Vitamin D did not reduce mortality (too infrequent)- Feb 2022monthly) will reduce mortality – results due 2024 19 Apr, 2016
Prediabetics not helped by 50,000 IU of vitamin D weekly and Calcium– Jan 2013 03 Apr, 2016
New Zealand – new 50,000 IU vitamin D capsule has soy which can cause allergic reactions – March 2016 09 Mar, 2016
Knee osteoarthritis reduced somewhat by 50,000 IU vitamin D monthly (need more) – RCT Aug 2015 08 Mar, 2016
50,000 IU of dry vitamin D needed at least daily following obesity surgery – forum Jan 2016 16 Feb, 2016
Pain of Diabetic Neuropathy reduced with weekly 50,000 IU vitamin D– CT Feb 2015 22 Oct, 2015
Vitamin D loading dose then weekly 50,000 IU not help (COPD) if very deficient – Oct 2015 16 Oct, 2015
Preeclampsia reduced by Vitamin D (50,000 IU bi-weekly) and Calcium – Oct 2015 15 Oct, 2015
Gestational diabetes reduced by just two 50,000 IU doses of vitamin D – RCT Nov 2014 02 Oct, 2015
Vitamin D is very important during pregnancy – 4,000 daily or 50,000 weekly - review Jan 2015 02 Oct, 2015
Vitamin D more than 40 ng: 1300 IU 50% chance: 5,000 IU 80% chance - Aug 2014 13 Sep, 2015
Children getting 60,000 IU monthly got to vitamin D level of 33 ng – Sept 2015 10 Sep, 2015
Hives treatment augmented by 60,000 IU Vitamin D weekly – RCT June 2015 22 Aug, 2015
Vitamin D levels of HIV and non HIV equally restored with 50,000 IU twice a week - July 2015 24 Jul, 2015
Diabetes not treated by MONTHLY 50,000 IU vitamin D (which is not quite enough) – May 2015 12 Jul, 2015
Diabetes RCT we expect to fail just 50,000 IU monthly - July 2014 12 Jul, 2015
No multiple sclerosis relapses during pregnancy if 50,000 IU of Vitamin D weekly – RCT April 2015 21 Jun, 2015
Near the end of pregnancy 50,000 IU vitamin D weekly was great – RCT April 2013 08 Jun, 2015
Vitamin D video: calcification, narrow-band UV, 4,000 IU, 50 ng – Dr. DeLuca May 2015 04 Jun, 2015
Vitamin D toxicity after 50,000 IU daily for 2 years (no surprise) – April 2015 26 Apr, 2015
Pregnant mothers in Quatar needed more than weekly 50,000 IU Vitamin D – Nov 2013 28 Mar, 2015
Peripheral Neuropathy in type II Diabetes reduced a bit by 50,000 IU weekly of vitamin D – RCT Feb 2015 28 Mar, 2015
Lupus not treated by monthly 50,000 IU vitamin D (no surprise) – RCT April 2015 23 Mar, 2015
Pregnancy helped by single dose of 60,000 IU of Vitamin D – RCT March 2015 15 Mar, 2015
50,000 IU Vitamin D one time after birth helped – RCT Jan 2015 14 Jan, 2015
50,000 IU monthly safe to take without any vitamin D testing – RCT Dec 2013 22 Dec, 2014
Fibromyalgia pain with trazodone reduced by 50 percent with weekly 50,000 IU of vitamin D – RCT Nov 2014 22 Nov, 2014
Will vitamin D loading dose and 50,000 IU monthly will help after melanoma surgery – Oct 2014 24 Oct, 2014
Diabetes treated by 50,000 IU of vitamin D weekly with 1 g Calcium daily – RCT July 2014 14 Sep, 2014
Bronchial Asthma reduced with 60,000 IU monthly vitamin D – RCT Nov 2013 14 Sep, 2014
Vitamin D levels of seniors restored with 50,000 IU weekly for 8 weeks – April 2014 01 Sep, 2014
7 improvements in lives of veterans with chronic pain with 50,000 IU vitamin D weekly – June 2012 20 Aug, 2014
Asthma reduced by weekly 50,000 IU of vitamin D – RCT Aug 2014 03 Aug, 2014
Vitamin D repaired nerve in rat (50,000 IU daily dose equivalent for human) – June 2013 28 Jun, 2014
Gestational Diabetes mostly treated with just 2 doses of 50,000 IU of vitamin D – RCT Dec 2013 26 Jun, 2014
Death rate 2X higher at age 60 if low vitamin D - 180,000 in Israel May 2012 13 Jun, 2014
Optic neuritis progession into Multiple Sclerosis reduced 68 percent by 50,000 IU of vitamin D weekly 08 May, 2014
COPD helped by weekly 50,000 IU Vitamin D – Aug 2013 03 May, 2014
Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT Jan 2014 10 Apr, 2014
7100 IU vitamin D (50,000 weekly) significantly reduced fibromyalgia – 2009 20 Jan, 2014
Need to adjust cofactors if take 50,000 IU of vitamin D weekly – Nov 2013 12 Jan, 2014
50,000 IU of vitamin D monthly in winter gets most above 20 ng – RCT Nov 2013 21 Dec, 2013
50,000 IU vitamin D weekly increased levels by 52 ng normally, but only 28 ng if obese – Oct 2013 13 Nov, 2013
At least 5,000 IU Vitamin D to get to optimal 50 ng - LEF Nov 2013 11 Nov, 2013
60,000 IU vitamin D monthly with Calcium was safe but not enough in the winter – 2012 02 Nov, 2013
60,000 IU vitamin D monthly with daily Calcium was safe but not enough in the winter – 2012 02 Nov, 2013
Muscle strength in youth increased with 60,000 IU vitamin D per week and 1 g Calcium – April 2010 10 Aug, 2013
50,000 IU vitamin D 1-3 times per week helped obese patients in rehab. – May 2013 01 Aug, 2013
60,000 IU vitamin D weekly for 3 months lasts for another 3 months - April 2013 14 Jul, 2013
Fibromalgia reduced with 50,000 IU weekly vitamin D2 – Sept 2011 14 Dec, 2011
50,000 IU DAILY Vitamin D2 mistake detected after 2 months - March 2010 30 Nov, 2010
50,000 IU vitamin D suggested to prevent osteoporosis (weekly then monthly)– April 2019 No value for 'modification_date_major'


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