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HbA1c levels (Diabetes) reduced by monthly 50,000 IU of vitamin D – Dec 2017

Association of Glycosylated Hemoglobin Levels With Vitamin D Status

J Clin Med Res. 2017 Dec; 9(12): 1013–1018. doi: 10.14740/jocmr3227w, PMCID: PMC5687907
Badurudeen Mahmood Buhary,a Ohoud Almohareb,a Naji Aljohani,a,b Saleh Alrajhi,a Samer Elkaissi,a Suphia Sherbeeni,a Abdulrahman Almaghamsi,a Shawana Abdulhamid Khan,a and Mussa H. Almalkia,b,c

VitaminDWiki Summary

Note from corresponding author

  • 50,000 IU Vitamin D monthly for all groups for 9 months
  • Deficient groups got an 3 additional 50,000 IU/month for the first 2 months (50,000 IU weekly)

Interestingly the HbA1C dropped similar amounts (10% ==> 8%) for those with low, medium, and good levels of vitamin D


Perspective as to what a drop from 10% to 8% means


See also VitaminDWiki

Pages listed in BOTH the categories Diabetes and Intervention

 Download the PDF from VitaminDWiki

The discovery of vitamin D is one of medicine’s great achievements. Despite all the positive evidence emerging about the beneficial effect of vitamin D, we still find many are vitamin D deficient. The purposes of this study were to examine the association between serum 25-hydroxyvitamin D (25(OH)D) and glycosylated hemoglobin (HbA1c) levels, to test the hypothesis that lower 25(OH)D levels are associated with poorer glucose control in diabetes mellitus (DM) patients and to investigate the effect of vitamin D supplementation on HbA1c levels.

This was a prospective observational cohort study of all patients with type 1 and type 2 diabetes (above 12 years) who attended the outpatient clinics of a tertiary center in Riyadh. HbA1c and vitamin D levels were recorded prior to supplementation and after 9 months of supplementation with vitamin D. All patients were divided into four groups according to their vitamin D level and an association between 25(OH)D and HbA1c was tested.

Results showed that 73.1% of the patients had 25(OH)D levels < 50 nmol/L. We observed lowering of HbA1c after vitamin D supplementation (from mean HbA1c of 10.55 to 7.70). We found HbA1c to be inversely related to serum vitamin D levels (r = -0.14 (P < 0.0000002) before supplementation and -0.16 (P < 0.000001) after supplementation with vitamin D).

Advising patients with higher HbA1c to test their vitamin D level and correct any deficiency will result in better blood glucose control and benefit the patient’s overall health.

Created by admin. Last Modification: Thursday March 1, 2018 16:40:07 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
8995 HbA1C.jpg admin 22 Dec, 2017 22:04 31.97 Kb 82123
8994 HbA1C lowered by Vitamin D.jpg admin 22 Dec, 2017 22:04 23.28 Kb 4202
8993 Glycosylated Hemoglobin.pdf admin 22 Dec, 2017 22:03 635.28 Kb 658