Effect of Vitamin D supplementation on symptoms and C-reactive protein in migraine patients
Journal of Research in Medical Sciences
Tayebeh Mottaghi, Gholamreza Askari, Fariborz Khorvash, Mohammad Reza Maracy
Background: Migarine is the most common headache around the world including Iran. In recent years, Vitamin D deficiency has been shown to a global health problem. A few studies have been determined inverse association between serum levels of Vitamin D with a headache. So, in this study, we investigated the effect of Vitamin D supplementation on symptoms and C-reactive protein(CRP) among patients with migraine.
Materials and Methods: This study was randomized, double-blind, and controlled-placebo clinical trial. Sixty-five migraine patients aged 10-61 years were included for analysis. Vitamin D was administrated for 10 weeks with 50,000 IU dosage of Vitamin D per week. Multivariate analysis of covariate and univariate analysis of covariate were done to determine the effects of Vitamin D supplementation on symptoms, including severity, duration, frequency of headache, and the headache diary result (HDR).
Results: Mean headache frequency and HDR had significant difference among two groups (5.9 ± 7.0 vs. 7.0 ± 6.0, P = 0.06 and 85.0 ± 134.2 vs. 132.1 ± 147.1, P = 0.04). But, a mean difference of headache frequency was marginally significant (P = 0.06). These values were lower among the intervention group compared to placebo group. The association was not observed between CRP with migraine disease.
Conclusion: In this study, we shown Vitamin D supplementation may be useful in decreasing frequency of headache attacks and HDR among patients with migraine.
See also VitaminDWiki
Headaches helped by Vitamin D in 7 studies – Jan 2020
Pages listed in BOTH the categories Headache and Magnesium
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- Headache
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48 items along with related searches which has the following Migraine Headaches associated with metal excess/deficiencies - July 2015
Compared blood levels of 25 with migraines to 25 withoutMetal Migraine No Migraine Ratio Cadmium 0.36 ug 0.09 ug 4X MORE Iron 0.97 ug 0.48 ug 2X MORE Lead 1.48 ug 0.78 ug 2X MORE Magnesium 10.6 ug 34.5 ug 3.5X LESS Zinc 0.24 ug 5.77 ug 24X LESS - Zinc and Vitamin D category listing has
90 items along with related searches Speculation by VitaminDWiki
Significant migraine reduction if use 10,000 IU of vitamin D, Magnesium, and perhaps Zinc- Cadmium liver problem 5 X less likely when vitamin D is greater than 40 ng – April 2018
The study found 5X fever Cadium lever problems with vitamin D > 40 ng
See also web
- Vitamin D supplementation may help patients with migraines, according to RCT
Vitamin D Council on this same study
Migraine headaches reduced with 50,000 IU vitamin D weekly – RCT July 2015Printer Friendly Follow this page for updates8210 visitors, last modified 14 Jan, 2021, This page is in the following categories (# of items in each category) - Cadmium liver problem 5 X less likely when vitamin D is greater than 40 ng – April 2018
- Zinc and Vitamin D category listing has