Type 1 diabetes 1.6 times more likely if a Vitamin D Receptor problem – Feb 2017

Note: Increased Risk = 1.66 is buried deep inside of the PDF, it is highlighted in yellow

• Type 1 Diabetes association with poor Vitamin D Receptor: 39 studies – April 2017

Overview Diabetes and vitamin D contains the following summary

• Diabetes is 5X more frequent far from the equator
• Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
• Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
• Sedentary people get less sun / Vitamin D
• Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
• Elderly get 4X less vitamin D from the same amount of sun
      Elderly also spend less time outdoors and have more clothes on
• All items in category Diabetes and Vitamin D 529 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

• Appears that >2,000 IU will Prevent
• Appears that >4,000 IU will Treat , but not cure
• 90% less T2 Diabetes in the group having lots of Vitamin D
• Appears that Magnesium helps both Prevention and Treatment
• Many diabetics would be better treated if Gut-Friendly Vitamin D were used

Number of articles in both categories of Diabetes and:
'This list is automatically updated''

• Dark Skin 24;   Intervention 56;   Meta-analysis 38;   Obesity 34;  Pregnancy 43;   T1 (child) 39;  Omega-3 11;  Vitamin D Receptor 23;  Genetics 12;  Magnesium 27    Click here to see details

Some Diabetes studies

• Type 2 Diabetes treated by Vitamin D (often 50,000 IU weekly) – meta-analysis July 2023
• Diabetic inflammation synergistically decreased by Vitamin D and exercise – RCT June 2022
• Incidence of Type-2 Diabetes increased 3X in 30 years (by the way, Vitamin D helps) – July 2022
• Vitamin d treats Type II Diabetes in many ways (14 article review) - Sept 2021
• T2 Diabetes 30 percent more likely if poor Vitamin D Receptor – meta-analysis of 47 studies – July 2021
• Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021

50 ng of Vitamin D fights Diabetes

• Saudi study defines normal Vitamin D level to be 50 to 70 ng (diabetes, etc.) - June 2020
• Diabetes 5X less likely if more than 50 ng of Vitamin D – April 2018

T1 Diabetes

• T1 Diabetes 3X lower risk if high vitamin D (over 40 ng) – Meta-analysis Nov 2020
• Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies – Sept 2019
• Type 1 Diabetes prevention with Vitamin D and Omega-3 – Symposium April 2019

Pre-Diabetes

• 4X reduction in prediabetes progressing to T2D if more than 50 ng of vitamin D – RCT March 2023
• Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021
• Prediabetes 1.5 X more likely to go away if take Vitamin D – meta-analysis July 2020

Diabetes, Metabolic Syndrome and Magnesium - many studies

Pages listed in BOTH of the categories Diabetes and Vitamin D Receptor

Vitamin D Receptor category has the following
Note that T2 diabetes has a similar increased risk

496 studies in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells

See also: 47 studies in the Resveratrol category

It appears that 30% of the population have a poor VDR (40% of the Obese )
Several diseases protect themselves by deactivating the Vitamin D receptor. Example: Breast Cancer
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The Vitamin D Receptor is associated with many health problems

Health problems include: Autoimmune (18 studies), Breast Cancer (20 studies), Colon Cancer (13 studies), Cardiovascular (23 studies), Cognition (16 studies), Diabetes (23 studies), Hypertension (9 studies), Infant (21 studies), Lupus (6 studies), Metabolic Syndrome (3 studies), Mortality (4 studies), Multiple Sclerosis (11 studies), Obesity (15 studies), Pregnancy (24 studies), Rheumatoid Arthritis (10 studies), TB (8 studies), VIRUS (33 studies),   Click here for details
Some health problems, such as Breast Cancer, Diabetes, and COVID protect themselves by reducing VDR activation

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55 health problems associated with poor VDR

A poor VDR is associated with the risk of 55 health problems  click here for details
The risk of 48 diseases at least double with poor VDR as of Jan 2023  click here for details
Some health problem, such as Breast Cancer reduce the VDR

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR

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How to increase VDR activation

Compensate for poor VDR by increasing one or more:

Increasing	Increases
1) Vitamin D supplement  Sun Ultraviolet -B	Vitamin D in the blood and thus in the cells
2) Magnesium	Vitamin D in the blood  AND in the cells
3) Omega-3	Vitamin D in the cells
4) Resveratrol	Vitamin D Receptor
5) Intense exercise	Vitamin D Receptor
6) Get prescription for VDR activator    paricalcitol, maxacalcitol?	Vitamin D Receptor
7) Quercetin (flavonoid)	Vitamin D Receptor
8) Zinc is in the VDR	Vitamin D Receptor
9) Boron	Vitamin D Receptor ?, etc
10) Essential oils e.g. ginger, curcumin	Vitamin D Receptor
11) Progesterone	Vitamin D Receptor
12) Infrequent high concentration Vitamin D Increases the concentration gradient	Vitamin D Receptor
13) Sulfroaphane and perhaps sulfur	Vitamin D Receptor
14)Butyrate especially gut	Vitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above

Far healthier and stronger at age 72 due to supplements Includes 6 supplements that help the VDR

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Increased risk associated with a poor Vitamin D Receptor
   Note: Some diseases reduce VDR activation
those with a * are known to decrease activation

Risk increase	Health Problem
50	Lyme Disease *
28	Leprosy - another says 3X
15	Chronic Heart Failure
15	Temporary hair loss
14,7	Childhood solid cancers
14	Hand, Foot, and Mouth disease
13	Sepsis
12	COVID Death
11	Metabolic Syndrome
9.6	Chronic Periodontitis    and smoke
8	Juvenile Rheumatoid Arthritis
7.6	Crohn's disease
7.5	Respiratory Tract Infections
5.8	Low back pain in athletes
5	Respiratory Distress in preemies
5	Ulcerative Colitis
5	Coronary Artery Disease
5	Asthma Child see also 1.3, 2.0 and 3.6
4.6	Breast Cancer * 16.9 X another study
4.3	Severe COVID in kids
4.1	Vitiligo
4	Polycystic ovary syndrome
3.8	Lupus
3.6	Pneumonia - children
3.3	Pre-term birth
3.1	Colon Cancer survival
3	Multiple Sclerosis
3	Dengue
3	Waist size
3	Ischemic Stroke
3	Alzheimer’s 9X in women
3	Parkinson’s
3	Gestational Diabetes
2.9	Hand, Foot, Mouth Disease
2.8	Osteoporosis & COPD
2.7	Gastric Cancer
2.6	Lupus in children
2.5	Lumbar Disc Degeneration
2.4	Lung Cancer
2.3	Cardio
2.3	Autism
2.2	Juvenile idiopathic arthritis
2.1	Adolescent idiopathic scoliosis in Asians
2	Diabetic Retinopathy
2	Parkinson's
2	Wheezing/Asthma see also 5X
2	Melanoma   Non-melanoma Skin Cancers
2	Myopia
2	Preeclampsia
1.9	Uterine Fibroids
1.9	Early tooth decay
1.8	Diabetic nephropathy
1.8	Sleep Apnea
1.6	Diabetes - Type I
1.6	Prostate Cancer while black
1.5	Diabetes -Type II
1.5	Gout
1.5	Pertussis
1.5	Obesity
1.4	Graves Disease
1.4	Rheumatoid arthritis
1.3	Hypertension
1.3	Childhood asthma see also 5X
1.3	Psoriasis in Caucasians
1.3	Tuberculosis
??	Rickets - Vitamin D resistant