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Vitamin D receptor is activated somewhat by ginger, thyme, coriander, and lemongrass – March 2018

Assessment of endocrine disruption potential of essential oils of culinary herbs and spices involving glucocorticoid, androgen and vitamin D receptors

Food and Function Journal, 10.1039/C7FO02058A
Iveta Bartonkova and Zdenek Dvorak

VitaminDWiki

I wish I knew how strongly the herbs increase the amount of vitamin D getting to cells
I suspect that increasing the Vitamin D dose size provides more benefit than the increasing the herbs
Henry Lahore, founder of VitaminDWiki


Vitamin D Receptor category has the following

370 studies in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells
It appears that 30% of the population has a poor VDR (40% of the Obese )

A poor VDR increases the risk of 55 health problems  click here for details
The risk of 44 diseases at least double with poor Vitamin D Receptor as of Oct 2019

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR

Compensate for poor VDR by increasing one or more:

IncreasingIncreases
1) Vitamin D supplement
  Sun, Ultraviolet -B
Vitamin D in the blood
and thus in the cells
2) MagnesiumVitamin D in the blood
 AND in the cells
3) Omega-3 Vitamin D in the cells
4) Resveratrol Vitamin D Receptor
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDRVitamin D Receptor
9) BoronVitamin D Receptor ?,
etc
10) Essential oils e.g. ginger, curcuminVitamin D Receptor
11) ProgesteroneVitamin D Receptor
12) Infrequent high concentration Vitamin D
Increases the concentration gradient
Vitamin D in the cells
13) Sulfroaphone and perhaps sulfurVitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above

Far healthier and stronger at age 72 due to supplements Includes 6 supplements which help the VDR

If poor Vitamin D Receptor

Risk
increase
Health Problem
50Lyme Disease
28Leprosy - another says 3X
15Chronic Heart Failure
15Temporary hair loss
14Hand, Foot, and Mouth disease
13Sepsis
11Metabolic Syndrome
9.6Chronic Periodontitis
   and smoke
8Juvenile Rheumatoid Arthritis
7.6Crohn's disease
7.5Respiratory Tract Infections
5.8Low back pain in athletes
5 Respiratory Distress in preemies
5Ulcerative Colitis
5Coronary Artery Disease
5Asthma Child see also 1.3, 2.0 and 3.6
4.6Breast Cancer 16.9 X another study
4.1Vitiligo
4Polycystic ovary syndrome
3.6 Pneumonia - children
3.3 Pre-term birth
3.1 Colon Cancer survival
3 Multiple Sclerosis
3Dengue
3 Waist size
3 Ischemic Stroke
3Alzheimer’s
3Gestational Diabetes
2.9Hand, Foot, Mouth Disease
2.8Osteoporosis & COPD
2.7Gastric Cancer
2.6Lupus in children
2.5 Lumbar Disc Degeneration
2.4Lung Cancer
2.3Autism
2.2Juvenile idiopathic arthritis
2.1Adolescent idiopathic scoliosis in Asians
2Diabetic Retinopathy
2Parkinson's
2 Wheezing/Asthma see also 5X
2 Melanoma   Non-melanoma Skin Cancers
2Myopia
2Preeclampsia
1.9Uterine Fibroids
1.9Early tooth decay
1.8Diabetic nephropathy
1.8Sleep Apnea
1.6Diabetes - Type I
1.6Prostate Cancer while black
1.5 Diabetes -Type II
1.5Pertusus
1.5Obesity
1.4Graves Disease
1.4 Rheumatoid arthritis
1.3Childhood asthma see also 5X
1.3Psoriasis in Caucasians
1.3Tuberculosis
?? Rickets - Vitamin D resistant

Ginger on the web

 Download the PDF from Sci-Hub via VitaminDWiki
Image
Image
  # = not tested

Essential oils (EOs) of culinary herbs and spices are consumed on common bases. They are multicomponent mixtures of compounds with already demonstrated biological activities. Taking in account regular dietary intake and the chemical composition of EOs, these may be candidates for endocrine disrupting entities. Therefore, we examined the effects of 31 EOs of culinary herbs and spices on the transcriptional activities of glucocorticoid receptor (GR), androgen receptor (AR) and vitamin D receptor (VDR). Using reporter gene assays in stably transfected cell lines, weak anti-androgen and anti-glucocorticoid activity was observed for EO of vanilla and nutmeg, respectively.

Moderate augmentation of calcitriol-dependent VDR activity was caused by EOs of

  • ginger,
  • thyme,
  • coriander and
  • lemongrass.

Mixed anti-glucocorticoid and VDR-stimulatory activities were displayed by EOs of turmeric, oregano, dill, caraway, verveine and spearmint.
Remaining 19 EOs were inactive against all receptors under investigation. Analyses of GR, AR and VDR target genes by the means of RT-PCR confirmed VDR-stimulatory, but not anti-glucocorticoid and anti-androgen effects of EOs. In conclusion, while we observed minor effects of several EOs on transcriptional activities of GR, AR and VDR, the toxicological significance is very low. Hence, 31 EOs of culinary herbs and spices may be considered safe, in terms of endocrine disruption involving receptors GR, AR and VDR.


Created by admin. Last Modification: Monday February 17, 2020 16:38:04 GMT-0000 by admin. (Version 4)

Attached files

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9666 Essential Oils 2.jpg admin 08 Apr, 2018 09:35 161.51 Kb 363
9665 Essential Oils.jpg admin 08 Apr, 2018 09:35 48.93 Kb 389
9664 Essential Oils.pdf PDF 2018 admin 08 Apr, 2018 09:34 1.42 Mb 213
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