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Vitamin D receptor is activated somewhat by ginger, thyme, coriander, and lemongrass – March 2018

Assessment of endocrine disruption potential of essential oils of culinary herbs and spices involving glucocorticoid, androgen and vitamin D receptors

Food and Function Journal, 10.1039/C7FO02058A
Iveta Bartonkova and Zdenek Dvorak


I wish I knew how strongly the herbs increase the amount of vitamin D getting to cells
I suspect that increasing the Vitamin D dose size provides more benefit than the increasing the herbs
Henry Lahore, founder of VitaminDWiki

Vitamin D Receptor category has the following

228 items in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells

A poor VDR increases the risk of 45 health problems  click here for details

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR
You can compensate for poor VDR by increasing one or more of the following:

1) Vitamin D supplement
  Sun, Ultraviolet -B
Vitamin D in the blood
and thus to the cells
2) MagnesiumVitamin D in the blood
 AND to the cells
3) Omega-3 Vitamin D to the cells
4) Resveratrol Vitamin D to the cells
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDR
Costs less than 1 cent per day
Vitamin D Receptor

See chart at the bottom of VDR page for Magnesium, Omega-3 and Resveratrol

If poor Vitamin D Receptor

Health Problem
9.6Chronic Periodontitis
   and smoke
8Juvenile Rheumatoid Arthritis
7.6Crohn's disease
7.5Respiratory Tract Infections
5.8Low back pain in athletes
5Ulcerative Colitis
5Coronary Artery Disease
4.6Breast Cancer
4polycystic ovary syndrome
3.6 Pneumonia - children
3.3 Pre-term birth
3.1 Colon Cancer survival
3 Multiple Sclerosis
3 Waist size
3 Ischemic Stroke
2.8Osteoporosis & COPD
2.7Gastric Cancer
2.6Lupus in children
2.5 Lumbar Disc Degeneration
2.4Lung Cancer
2.2Juvenile idiopathic arthritis
2.1Adolescent idiopathic scoliosis in Asians
2Diabetic Retinopathy
2 Wheezing/Asthma
2 Melanoma   Non-melanoma Skin Cancers
1.9Uterine Fibroids
1.9Early tooth decay
1.8Diabetic nephropathy
1.6Diabetes - Type I
1.6Prostate Cancer while black
1.5 Diabetes -Type II
1.4 Rheumatoid arthritis
1.3Childhood asthma

 Download the PDF from Sci-Hub via VitaminDWiki
  # = not tested

Essential oils (EOs) of culinary herbs and spices are consumed on common bases. They are multicomponent mixtures of compounds with already demonstrated biological activities. Taking in account regular dietary intake and the chemical composition of EOs, these may be candidates for endocrine disrupting entities. Therefore, we examined the effects of 31 EOs of culinary herbs and spices on the transcriptional activities of glucocorticoid receptor (GR), androgen receptor (AR) and vitamin D receptor (VDR). Using reporter gene assays in stably transfected cell lines, weak anti-androgen and anti-glucocorticoid activity was observed for EO of vanilla and nutmeg, respectively.

Moderate augmentation of calcitriol-dependent VDR activity was caused by EOs of

  • ginger,
  • thyme,
  • coriander and
  • lemongrass.

Mixed anti-glucocorticoid and VDR-stimulatory activities were displayed by EOs of turmeric, oregano, dill, caraway, verveine and spearmint.
Remaining 19 EOs were inactive against all receptors under investigation. Analyses of GR, AR and VDR target genes by the means of RT-PCR confirmed VDR-stimulatory, but not anti-glucocorticoid and anti-androgen effects of EOs. In conclusion, while we observed minor effects of several EOs on transcriptional activities of GR, AR and VDR, the toxicological significance is very low. Hence, 31 EOs of culinary herbs and spices may be considered safe, in terms of endocrine disruption involving receptors GR, AR and VDR.

Created by admin. Last Modification: Sunday April 8, 2018 09:41:54 UTC by admin. (Version 3)

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9666 Essential Oils 2.jpg admin 08 Apr, 2018 09:35 161.51 Kb 70
9665 Essential Oils.jpg admin 08 Apr, 2018 09:35 48.93 Kb 74
9664 Essential Oils.pdf PDF 2018 admin 08 Apr, 2018 09:34 1.42 Mb 30
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