The relationship between vitamin D receptor gene polymorphism and deciduous tooth decay in Chinese children.
BMC Oral Health. 2017 Jul 11;17(1):111. doi: 10.1186/s12903-017-0398-x.
Kong YY1,2, Zheng JM3, Zhang WJ2, Jiang QZ4,5, Yang XC6, Yu M7, Zeng SJ8.
- Periodontitis probably related to low Vitamin D – review June 2018
- Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
- Chronic Periodontitis 9.6 times more likely if smoke and have poor Vitamin D Receptor – Aug 2016
- Dental carries associated with poor vitamin D receptor (TaqI genotypes) – 2016
Vitamin D Receptor category has the following:
Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells
A poor VDR increases the risk of 45 health problems click here for details
VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR
You can compensate for poor VDR by increasing one or more of the following:
|1) Vitamin D supplement|
Sun, Ultraviolet -B
| Vitamin D in the blood |
and thus to the cells
|2) Magnesium||Vitamin D in the blood |
AND to the cells
|3) Omega-3||Vitamin D to the cells|
|4) Resveratrol||Vitamin D to the cells|
|5) Intense exercise||Vitamin D Receptor|
|6) Get prescription for VDR activator|
|Vitamin D Receptor|
|7) Quercetin (flavonoid)||Vitamin D Receptor|
|8) Zinc is in the VDR|
Costs less than 1 cent per day
|Vitamin D Receptor|
If poor Vitamin D Receptor
|9.6||Chronic Periodontitis |
|8||Juvenile Rheumatoid Arthritis|
|7.5||Respiratory Tract Infections|
|5.8||Low back pain in athletes|
|5||Coronary Artery Disease|
|4||polycystic ovary syndrome|
|3.6||Pneumonia - children|
|3.1||Colon Cancer survival|
|2.8||Osteoporosis & COPD|
|2.6||Lupus in children|
|2.5||Lumbar Disc Degeneration|
|2.2||Juvenile idiopathic arthritis|
|2.1||Adolescent idiopathic scoliosis in Asians|
|2||Melanoma Non-melanoma Skin Cancers|
|1.9||Early tooth decay|
|1.6||Diabetes - Type I|
|1.6||Prostate Cancer while black|
|1.5||Diabetes -Type II|
In the present study, we explored the link between vitamin D receptor (VDR) BsmI, TaqI, ApaI and FokI gene polymorphisms with deciduous tooth decay in Chinese children.
Our study included 380 Chinese children aged 4-7 years, whose DNA sample was collected from the buccal mucosa. VDR gene polymorphisms was determined by PCR-RFLP.
The adjusted logistic regression analysis demonstrated that BsmI containing the Bb genotype was linked with the increased risk of deciduous tooth decay (OR = 1.856, 95% CI = [1.184, 2.908], p = 0.007). However, VDR polymorphisms ApaI, TaqI and FokI were not associated with deciduous tooth decay (ApaI: OR = 0.839, 95% CI = [0.614, 1.145], p = 0.268; TaqI: OR = 1.150, 95% CI = [0.495, 2.672], p = 0.744; FokI: OR = 0.856, 95% CI = [0.616, 1.191], p = 0.356).
Our results showed that VDR BsmI polymorphism was associated with the risk of deciduous tooth decay in Chinese children aged 4-7 years. However, the specific mechanism remains to further verify through experiment.
PMID: 28697775 DOI: 10.1186/s12903-017-0398-x
Association between Single Nucleotide Polymorphisms in Vitamin D Receptor Gene Polymorphisms and Permanent Tooth Caries Susceptibility to Permanent Tooth Caries in Chinese Adolescent