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Long-haul fatigue, etc. common after viral infections (SARS1,2, MERS, Swine, 1918,...)


  • Some people have long-term health problems after any viral infection
  • The exact fraction of people varies with the virus - varies from 10% to 60%
  • The long-term problems can extend for months to years.
    • Sometimes the damage is permanent - example = lungs
  • It is too early (Aug ) to know if long-term COVID-19 problems will last for more than 3 months
  • The long-term problems occur without having had serious symptoms
  • It appears that long-term COVID-19 problems favor women and those of middle age
    • vs COVID-19 favors men and elderly
  • The most common long-term problem is Chronic Fatigue
    • Note to Athletes: Exercise can make Chronic Fatigue symptoms worse

Vitamin D might help viral infections in many ways

  • Reduce the risk of getting any enveloped viral infection
  • Reduce the risk of getting a severe infection
  • Normalize the immune system which has locked-on, which results in long-term problems
  • Vitamin D can inhibit most enveloped virus
  • Additional enveloped virus include: Epstein-Barr virus- Mononucleosis, Ebola, cold sore, Shingles, cytomegalovirus, Hepatitis B, HIV, Dengue, Yellow fever, Measles, Mumps, smallpox,
    • and all previous Coronavirus, such as SARS, MERS (no data yet on SARS-2 - too new)
  • Swine Flu Influenza (H1N1) of 2009 Wikipedia
    • Infected ~1 Billion, Killed ~284,000

80 percent of COVID-19 survivors have long-haul symptoms – meta-analysis Jan 30, 2021

Long-COVID in VitaminDWiki

Probably less long-haul COVID-19 when immune system was regenerated by Vitamin D, etc. – Dec 2020

Probably fewer long-haul COVID-19 problems when rejuvenated immune system (Vitamin D, etc.)– Dec 2020

Several alternative COVID-19 treatments greatly reduce long-haul symptoms - Feb 2021

Mercola - Feb 2021

  • Using various combinations of nebulized peroxide oral vitamin A, vitamin C and vitamin D, iodine, intravenous hydrogen peroxide and iodine as well as intravenous (IV) vitamin C, and hydroxychloroquine
    • Note: Most of the alternatives boost the immune system

Snips from reports of Long-haul Covid = longcovid = post-Covid syndrome

  • Sequelae in Adults at 6 Months After COVID-19 Infection JAMA Feb 2021
    • "as long as 9 months after illness, approximately 30% reported persistent symptoms"
  • 77 Clinical trials for long-haul COVID As of Jan 8, 2021
    • Note: There are more trials for long-haul than for Vitamin D treatment of COVID-19
  • Long-Haul COVID-19: Putative Pathophysiology, Risk Factors, and Treatments - Dec 10, 2020
    • One puzzling feature of long-haul COVID-19 is that it is not predicted by initial disease severity.
    • Long-haul COVID-19 affects even mild-to-moderate cases and younger adults that do not require respiratory support or intensive care.


    • {ATTACH(inline="1" id="14833" icon="1")}Download the PDF from VitaminDWiki{ATTACH
  • ‘Long haul’ Covid: With almost 600,000 UK sufferers, the professor studying post-Covid syndrome tells us what we know so far Aug 12, 2020
    • found 12 % have symptoms longer than 30 days, and one in 200 for more than 90 days.
    • post-Covid syndrome, who tend to not be so ill they need hospitalization,
      • but can find themselves bed-bound and unable to work?
    • ..found a “slight excess of females to males”, roughly 60:40, and says it impacts most age groups, and more so in those in their thirties and forties. “Older people don’t tend to get long-term symptoms,.."
  • 6 Diver's lungs permanently damaged by COVID-19 April 2020
    • and, they did not even go into a hospital
    • But none of them can dive anymore. "The damage to the lungs is irreversible,"
  • Fatigue plagues thousands suffering post-coronavirus symptoms Financial Times Aug 2, 2020
    • "Referred to as long-haul Covid, longcovid, or tentatively by the medical community as ‘post-Covid syndrome’,.."
    • " Recent analysis by the Covid Symptom Study suggested that as many as one in 10 people with Covid-19 have been sick for more than three weeks after symptoms first emerge. Some of the most pernicious problems faced by the group of long-haulers are chronic fatigue, high temperature, insomnia, headaches, brain fog, tingling sensations and dizziness."
    • " John Geddes, professor of epidemiology at the University of Oxford, believes that protracted illness is likely to be caused by the virus getting into the nerve cells of the brain. Others suggest that an elevated immune response to the virus may be damaging the cells in key parts of the body."
    • " Following the 2003 Sars outbreak in Asia, researchers found that 60 per cent of patients had post-viral fatigue and insomnia one year after contracting the virus. "
    • " The Ebola outbreak in west Africa in 2014 led to the identification of a unique “post-Ebola Syndrome”, which shared some symptoms with chronic fatigue and lasted up to two years after infection. "
  • 55 % of coronavirus patients still have neurological problems three-months later behind paywall Aug 6, 2020
  • I’m a COVID-19 long-hauler and an epidemiologist – here’s how it feels when symptoms last for months Aug 11, 2020
    • COVID-19 support groups show that there are many people not considered sick enough to be hospitalized – yet they are experiencing symptoms worse than the flu. It is possible COVID-19 is neurotoxic and is one of the first illnesses capable of crossing the blood-brain barrier. This might explain why many people like me have neurological problems. Many long-haulers are experiencing post-viral symptoms similar to those caused by mononucleosis and myalgic encephalomyelitis/chronic fatigue syndrome.
    • A big challenge long-haulers face may be sustaining employment. Ultimately, it is too early to classify long-haulers as having a disability. Anthony Fauci reported that “it will take months to a year or more to know whether lingering COVID-19 symptoms in young people could be chronic illnesses.”
    • Influenza has long been linked to persistent symptoms such as fatigue and muscle pain,
      • including after both the 1890 and 1918-19 pandemics.
    • Survival of a severe viral pneumonia or ARDS, particularly after intensive care, is known to have long-lasting implications. Some survivors suffer long-term breathlessness and fatigue as a result of the damage to their lungs or from other complications. Survivors can also suffer depression (26–33%), anxiety (38–44%), or post-traumatic stress disorder (22–24%).
  • Here’s what we know so far about the long-term symptoms of COVID-19 July 26, 2020
    • Canadian researchers followed survivors of the first SARS outbreak in Toronto. They found sleep disturbance, chronic fatigue, depression and muscle pains were common. A third of survivors had to modify their work and lifestyle, and only 14% had no long-term symptoms.
    • Similarly, in a Korean group of MERS survivors, 48% still experienced chronic fatigue after 12 months
  • Long-haulers are redefining COVID-19 Aug 26
    • Some potential treatments we have learned from management of fatigue syndrome/fibromyalgia/myalgic encephalomyelitis syndrome that may be transferrable to post-COVID patients are:
      • 1. Energy support for severe fatigue: CoQ10, ashwaganda, ginseng, DHEA, high potency B vitamins, carnitine and hormones.
      • 2. Immune support: Vitamins C, D, zinc, mushroom extract, probiotics, sleep and stress management.
      • 3. Inflammation: anti-inflammatory diet, Zyflamend, fish oil, turmeric and ginger (activate VDR).
      • 4. Pain management, mood and brain issues: cognitive behavioral therapy, mindfulness, meditation, graded mental and physical rehabilitation exercises, acupuncture, yoga, tai chi, SAMe, ginkgo, cannabinoids, magnesium and medications.
  • dysautonomia: heart, brain, gastrointestinal and immune systems. Headaches, diarrhea, shortness of breath, chest pain, mood disorders, brain fog and profound fatigue with minimal exertion can characterize this condition.


  • Long-lasting COVID-19 symptoms: Patients want answers Aug 11
    • "A small study of 143 previously hospitalized, recovering patients in Italy found that 87.4% of the cohort had at least one persistent symptom 2 months or longer after initial onset and at more than a month after discharge."
  • Covid-19 Long Haulers: Meaning, Symptoms, Support Groups July 12
    • Italian study: "At an average of 60 days after initial onset of symptoms, only “12.6% were completely free of any COVID-19–related symptom, while 32% had 1 or 2 symptoms and 55% had 3 or more” 4. These patients were sent home, as if they were well, and yet they had symptoms. The most common symptoms were: “fatigue (53.1%), dyspnea (43.4%), joint pain, (27.3%) and chest pain (21.7%).” Dyspnea is difficulty breathing."
  • Management of post-acute covid-19 in primary care BMJ Aug 11 FREE PDF
    • "Approximately 10% of people experience prolonged illness after covid-19"
    • Image
  • Warp Speed Help for COVID Long Haulers and ME/CFS July 30
    • "... research on post-epidemic and post-infection recovery shows many viruses leave in their wake patients who experience an onset of post-viral fatigue and/or ME/CFS-like symptoms. This has been true of SARS, MERS, West Nile, H1N1 flu, Ebola and Epstein-Barr."
    • In March "I hope that COVID doesn’t lead to an increase in ME/CFS, but I suspect that… it’s something that we should be prepared for.”
    • "Fauci acknowledged three times in one week that LongCovid is “highly suggestive of myalgic encephalomyelitis and chronic fatigue syndrome.”
  • An Offering: ME/CFS Resources and Support for the COVID-19 Long Haulers Aug 5
    • " Indeed, the COVID-19 pandemic has had one salutary outcome – for the first time, people with post-infectious illnesses are being accounted for and are starting to be studied. Those studies, however, will take time."
    • "Many long-haulers reveal that these and other symptoms often worsen after attempting simple daily activities and mild exercise, placing some in a never-ending loop of illness and disability."
    • "I suspect people recovering at home and their doctors…do not realize it may be exertion—both mental and physical—that is causing their symptoms to return. Without instituting careful pacing, people suffer, and their recovery is delayed.” "
    • "Standard rehabilitation approaches (i.e., graded exercise) may be harmful and worsen prospects for recovery in the subset of long-haulers who experience symptom exacerbation after physical and cognitive activity."
    • ~30% of Hong Kong SARS survivors met the CDC’s criteria for chronic fatigue syndrome (CFS)
    • Questions
      • Is this the natural course of a SARS-CoV-19 infection for a subset of people?
      • Is this a form of post-viral fatigue?
      • are the long-term symptoms indicative of myalgic encephalomyelitis
  • Research Examines Links Between 'Long COVID' and ME/CFS Medscape Aug 24
    • "chronic fatigue was listed as the top symptom among individuals still feeling unwell beyond 2 weeks after COVID-19 onset."
    • "diagnostic criteria for ME/CFS, which is defined by substantial, profound fatigue for at least 6 months, postexertional malaise, unrefreshing sleep, and one or both of orthostatic intolerance and/or cognitive impairment. Although the etiology of ME/CFS is unclear, the condition commonly arises following a viral illness."
    • Toronto study: " SARS-CoV-1 and continued to report chronic fatigue, musculoskeletal pain, and disturbed and unrefreshing sleep with EEG-documented sleep disturbances 1 to 3 years following the illness. None had been able to return to work by 1 year.
    • "With ME/CFS, post-exertional malaise often involves a dramatic exacerbation of symptoms such as fatigue, pain, and cognitive impairment a day or two after exertion rather than immediately following it. In contrast, shortness of breath during exertion isn't typical of ME/CFS."
  • Coronavirus COVID-19 Long Term Effects - Researched & Explained Aug 9
    • "91% of respondents in the Confirmed Case Long-Hauler Survey of 1,500 individuals reported that they experienced extreme and chronic fatigue.
    • Symptoms: 82% >2 months, 41.9% >3 months, 12.5% >4 months.
    • Based on a study done at University Hospital Frankfurt in Germany, it appears as if heart damage is independent of the severity of the COVID-19 case.
  • Long after the fire of a Covid-19 infection, mental and neurological effects can still smolder Aug 12
    • "As many as 1 in 3 patients recovering from Covid-19 could experience neurological or psychological after-effects of their infections,"
      • headache, dizziness, and lingering loss of smell or taste to mood disorders and deeper cognitive impairment
  • What Medicine’s Own COVID Long-Haulers Have Faced The Atlantic Nov 24, 2021
  • To Help People With Long Covid, Scientists Need to Define It Wired Nov 24 2021,
    • "Patients with the perplexing syndrome have reported 200 different symptoms. Researchers will have to decide which to study—and rule out."
    • Study findings:"The thing that most predicted whether patients developed long Covid symptoms was whether they believed they had been infected, not whether their infection could be lab-confirmed."

See also in VitaminDWiki

Fibromyalgia and Chronic Fatigue


Items in both categories Virus and Vitamin D Receptor:


Influenza and Colds

Flu has the following
Vitamin D fights all phases of Influenza

Virus and Breathing studies:

60+ VitaminDWiki pages have LONG-HAUL or LONG-COVID in the title

Items found: 66
Title Modified
Some early Long-COVID symptoms persist for at least 3 years in US veterans – May 2024 02 Jul, 2024
Inflammation causes low iron, which triggers long-COVID – March 2024 04 Apr, 2024
Long-COVID 3.1 X more likely if insufficient amounts of Magnesium and Vitamin D – March 2024 24 Mar, 2024
Long-COVID a month shorter if more than 20 ng of Vitamin D - Jan 2024 31 Jan, 2024
Hypothesis: Both Long COVID and Vaccine Injury are caused by Spike Protein, proposed detox – Nov 2023 24 Nov, 2023
Long-COVID: Vitamin D was the only statistically significant factor - Oct 2023 31 Oct, 2023
Long COVID with Neuro-Cognitive symptoms had especially low vitamin D levels – Sept 2023 19 Sep, 2023
The ONLY Solution to Long COVID (Vitamin D) - video and transcript Sept 2023 12 Sep, 2023
Long-COVID can hide in the body for years in scores of locations – Sept 2023 09 Sep, 2023
One in five people with long COVID can no longer work (Doctors in this case) - Sept 2023 02 Sep, 2023
Number of people with long COVID could be vastly underestimated - Aug 2023 01 Sep, 2023
Long-COVID associated with 37 poor genes (no Vitamin D genes) – July 2023 03 Aug, 2023
COVID, Long-COVID and Vitamin D in children - Review April 2023 09 Jul, 2023
Fasting may reduce inflammation and long-COVID - June 2023 11 Jun, 2023
The US believes you have long-COVID if you have more than 12 points (no treatment yet) - May 2023 25 May, 2023
COVID, Long COVID, and Vitamin D – May 2023 06 May, 2023
2nd COVID infection increases the risk of Long-COVID - 2022 22 Jan, 2023
Vitamin D might also help the Long-COVID older adult – Jan 2023 07 Jan, 2023
Long-COVID fatigue reduced by Vitamin C and l-Arginine in one month– RCT Nov 2022 24 Nov, 2022
Adrenal, Long-COVID and Vitamin D - several studies 31 Oct, 2022
Long Covid, Short Magnesium - Chambers April 2022 30 Oct, 2022
Fatigue and other long-haul problems appear to be associated with low Magnesium - Chambers Oct 2022 30 Oct, 2022
Long-COVID symptoms in 10 Percent of women 3 months after infection (22 countries) – Oct 2022 29 Oct, 2022
Long-COVID is now the biggest COVID concern - many studies 16 Oct, 2022
Epstein-Barr Virus probably causes Long-COVID, CFS, and MS - many studies 02 Oct, 2022
Anti-oxidants and Long-Covid (Mg, Glutamate, Butyrate, etc) – Sept 2022 02 Oct, 2022
Chronic Fatigue Syndrome and long-haul COVID-19 26 Sep, 2022
Over Two Million Americans Aren’t Working Due to Long-COVID - Aug 2022 27 Aug, 2022
Long-COVID: often had not been hospitalized - May 2022 25 Aug, 2022
COVID virus persists in most body tissues (Long-COVID) - 2022 23 Aug, 2022
Long-COVID in VitaminDWiki 16 Aug, 2022
LONG-COVID may be permanent in 1 in 200 of people infected – July 2022 06 Aug, 2022
Long-Haul more prevalent among seniors - June - 2022 26 Jun, 2022
Long-Haul can now be claimed a work disability in the UK – June 2022 24 Jun, 2022
Half as much Long-Haul with Omicron - June 2022 19 Jun, 2022
Half as much Long-Haul with Omicron - June 2022 19 Jun, 2022
COVID Spike persists in Long Haul - June 2022 18 Jun, 2022
COVID Long-Haul prevalence increases with time: 50% at 4 months - meta June 2022 17 Jun, 2022
COVID and Magnesium - hypothesis, clinical trials, Long-Haul - Oct 2021 10 Jun, 2022
Mass disabling events: Polio, WWII, HIV, and COVID Long-Haul - June 2022 06 Jun, 2022
1 in 5 Americans who got COVID had Long-Haul for a while - CDC May 2022 27 May, 2022
Long-Haul COVID after 3 months – only 5 percent had even 30 ng of Vitamin D – April 2022 04 May, 2022
Hypothesis: 2 long-haul COVIDs: had mild symptoms and had needed ICU - April 2022 15 Apr, 2022
COVID Long-Haul at 49 weeks: overactive immune system, type O blood - March 2022 07 Apr, 2022
Children have less severe COVID, but just as much long-haul as adults - April 2022 06 Apr, 2022
Dietary Recommendations for COVID Long-Haul – March 2022 20 Mar, 2022
Mild Long-Haul 4.2 X more likely if type O blood - preprint March 16, 2022 20 Mar, 2022
Long-Haul COVID is somewhat less of a problem if vaccinated – Nov 2021 18 Mar, 2022
COVID long-haul: 1 million in US too sick to work, many cannot get compensation - March 2021 09 Mar, 2022
COVID Long-Haul NYT - Feb 2022 19 Feb, 2022
COVID Long-Haul fought by probiotics - Jan 2022 29 Jan, 2022
COVID Long-Haul predicted by 4 factors (Epstein-Barr virus, etc) – Jan 24, 2022 26 Jan, 2022
Some COVID-19 infection become COVID Long-Haul - Nov 2020 15 Dec, 2021
Long-haul after breakthrough COVID – Nov 2021 11 Dec, 2021
Long-haul, VAERS, Ivermectin, vaccines, etc. Drs. Seheult, Patrick: Video with table of contents - Sept 17, 2021 21 Sep, 2021
Your Brain on Covid-19 Long-Haul, Dr. Galland video and transcript - Aug 1, 2021 07 Aug, 2021
Long-haul COVID-19 blood tests at Mayo include vitamin D (but no results published) – July 2021 20 Jul, 2021
Most people with Long-Haul COVID-19 have low Vitamin D – July 2021 15 Jul, 2021
‘Long haul’ COVID rehab worse than cancer rehab, CDC – July 2021 13 Jul, 2021
Long-Haul COVID-19 occurred to 1 in 20 who had been asymptomatic (a study of 2 million with COVID-19) – June 2021 15 Jun, 2021
COVID-19 Long haul - excellent graph - systematic review May 26, 2021 26 May, 2021
COVID-19 vaccines look good in the short term, but probably not good for the long term 29 Apr, 2021
Long-haul COVID-19 - another hint that Vitamin D should help - Dec 2020 16 Apr, 2021
Probably fewer long-haul COVID-19 problems when rejuvenated immune system (Vitamin D, etc.)– Dec 2020 21 Feb, 2021
Long-haul fatigue, etc. common after viral infections (SARS1,2, MERS, Swine, 1918,...) 21 Feb, 2021
Long-distance truck drivers more likely to get COVID-19 (perhaps UVA)- July 2020 12 Aug, 2020

Created by admin. Last Modification: Sunday June 19, 2022 19:57:40 GMT-0000 by admin. (Version 49)

Attached files

ID Name Comment Uploaded Size Downloads
14834 Long Haul Dec.jpg admin 09 Jan, 2021 121.79 Kb 2610
14833 preprints202012.0242.v1.pdf admin 09 Jan, 2021 948.50 Kb 398
14227 long covid primary care.jpg admin 30 Aug, 2020 486.42 Kb 738
14226 Dysautonomia.jpg admin 30 Aug, 2020 157.16 Kb 796