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Long-haul after breakthrough COVID – Nov 2021


Long Covid after Breakthrough COVID-19: the postacute sequelae of breakthrough COVID-19

Research Square https://doi.org/10.21203/rs.3.rs-1062160/v1 preprint
Ziyad Al-Aly ( B zalaly at gmail.com ); Washington University School of Medicine https://orcid.org/0000-0002-2600-0434
Benjamin Bowe; VA Saint Louis Health Care System
Yan Xie; VA Saint Louis Health Care System https://orcid.org/0000-0002-2457-9382

Long-haul symptoms in Breakthru vs never infected

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Long-haul of VAXXed is less than UNVAXXed (hospital not mentioned)

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The post-acute sequelae of COVID-19 have been described1, but whether breakthrough COVID-19 (that is the disease that ensues following vaccine breakthrough SARS-CoV-2 infection) results in post-acute sequelae is not yet clear.
Here we use the national healthcare databases of the US Department of Veterans Affairs to characterize 6-month risks of incident post-acute sequelae in people with breakthrough COVID-19 who survived for at least 30 days after diagnosis. We show that compared to people with no evidence of COVID-19, beyond the first 30 days of illness, people with breakthrough COVID-19 exhibit a higher risk of death and broad array of incident post-acute sequelae in the pulmonary system, as well as extrapulmonary sequelae that include cardiovascular disorders, coagulation disorders, gastrointestinal disorders, general disorders (e.g., fatigue), kidney disorders, mental health disorders, metabolic disorders, musculoskeletal disorders, and neurologic disorders. Our analyses by care setting of the acute phase of the disease show that people who were not hospitalized during the first 30 days after diagnosis with breakthrough COVID-19 exhibit a small but not insignificant increase in risk of death and post-acute sequelae; the risks are further increased in people who were hospitalized during the acute phase of the disease.

Our comparative approach shows that people with breakthrough COVID-19 exhibit lower risks of death and post-acute sequelae than people with COVID-19 who were not previously vaccinated for it; and in analyses among individuals who were hospitalized during the acute phase of the disease, people with breakthrough COVID-19 exhibit higher risks of death and post-acute sequelae than people with seasonal influenza. Altogether, our findings show increased risks of death and post-acute sequalae in people with breakthrough COVID-19; the risks are evident among those who were not hospitalized during the acute phase of the disease. Our comparative approach provides context for understanding the risks in relation to COVID-19 without prior vaccination and seasonal influenza. The findings will inform the ongoing effort to optimize strategies for prevention of breakthrough SARS-CoV-2 infections and will guide development and optimization of post-acute care pathways for people with breakthrough COVID-19.
 Download the PDF from VitaminDWiki


VitaminDWiki titles with LONG-HAUL (15 as of Dec 2021)

Items found: 17
Title Modified
COVID-19 long haul - meta-analysis, Vitamin D, etc. 23 Dec, 2021
Some COVID-19 infection become COVID Long-Haul - Nov 2020 15 Dec, 2021
Epstein-Barr Virus may cause Long-Haul, CFS, and MS (Vitamin D should help) 11 Dec, 2021
Epstein-Barr virus appears to cause Long-Haul and Chronic fatiure Syndrome (Vitamin D might help) 11 Dec, 2021
Long-haul after breakthrough COVID – Nov 2021 11 Dec, 2021
Long-Haul COVID is a problem even if vaccinated (Veterans)– Nov 2021 24 Nov, 2021
Long-haul, VAERS, Ivermectin, vaccines, etc. Drs. Seheult, Patrick: Video with table of contents - Sept 17, 2021 21 Sep, 2021
Your Brain on Covid-19 Long-Haul, Dr. Galland video and transcript - Aug 1, 2021 07 Aug, 2021
Long-haul COVID-19 blood tests at Mayo include vitamin D (but no results published) – July 2021 20 Jul, 2021
Most people with Long-Haul COVID-19 have low Vitamin D – July 2021 15 Jul, 2021
‘Long haul’ COVID rehab worse than cancer rehab, CDC – July 2021 13 Jul, 2021
Long-Haul COVID-19 occurred to 1 in 20 who had been asymptomatic (a study of 2 million with COVID-19) – June 2021 15 Jun, 2021
COVID-19 Long haul - excellent graph - systematic review May 26, 2021 26 May, 2021
Long-haul COVID-19 - another hint that Vitamin D should help - Dec 2020 16 Apr, 2021
Chronic Fatigue Syndrome and long-haul COVID-19 02 Apr, 2021
Probably fewer long-haul COVID-19 problems when rejuvenated immune system (Vitamin D, etc.)– Dec 2020 21 Feb, 2021
Long-haul fatigue, etc. common after viral infections (SARS1,2, MERS, Swine, 1918,...) 21 Feb, 2021

Created by admin. Last Modification: Sunday December 12, 2021 01:32:32 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
16726 Long-haul if VAXX vs UNVAXX.jpg admin 11 Dec, 2021 17:52 65.82 Kb 30
16724 Long-haul breakthru.jpg admin 11 Dec, 2021 17:50 74.13 Kb 29
16723 Long Covid after Breakthrough_compressed.pdf PDF 2021 admin 11 Dec, 2021 17:49 578.22 Kb 16
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