Long-COVID in VitaminDWiki

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69+ VitaminDWiki pages have LONG-HAUL or LONG-COVID in the title

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Sexual dysfunction, hair loss also linked with long COVID - Aug 2022

MDEdge

• "They also found that people more likely to have persistent symptoms 3 months after COVID infection were also more likely to be young, female, smokers, to belong to certain minority ethnic groups, and to have lower socioeconomic status. They were also more likely to be obese and have a wide range of health conditions."
  • Many of the above problems are associated with low vitamin D
• Based on the study Symptoms and risk factors for long COVID in non-hospitalized adults - July 2022  PDF
  • The largest aHRs were for anosmia (aHR 6.49, 95% CI 5.02–8.39), hair loss (3.99, 3.63–4.39), sneezing (2.77, 1.40–5.50), ejaculation

difficulty (2.63, 1.61–4.28) and reduced libido (2.36, 1.61–3.47)

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US Gov. finally has a long-COVID plan - Aug 2022

The US Now Has a Research Plan for Long COVID—Is It Enough? JAMA Aug 12

• “Long COVID” = post-COVID conditions = PCC, = both direct and indirect effects,
• postacute sequelae of SARS-CoV-2 infection = PASC, includes only the direct effects.
• ",,, pointed out that it still needs congressional funding. She called the plan otherwise “underwhelming.”

 Download the study from VitaminDWiki

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At least 90 long Covid groups exist around the world in 34 countries. - Aug 2022

‘Left to rot’: The lonely plight of long Covid sufferers

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Many with long-COVID has low Cortisol levels (regulated by Vitamin D) - Aug 2022

Yale researchers have unearthed a new clue that may explain who has long COVID—and how to treat the chronic condition Fortune Magazine

• "...long COVID patients had half the levels of cortisol—a hormone that guides the body’s response to stress—as uninfected individuals and those who had recovered fully from COVID."

 Download the study from VitaminDWiki

• Cholesterol is needed to produce both Vitamin D and Cortisol
• YouTube: Cortisol (Stress) and Vitamin D Levels Dr Berg, April 2021

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About 10 million Americans have long-haul - April 2022

Washington Post

• "Under a memorandum issued by Biden, the Department of Health and Human Services will coordinate a government-wide action plan to address long covid, which is estimated to afflict anywhere from 7.7 million to 23 million Americans, according to a recent federal watchdog report."

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Long-Haul group in Facebook has 190,000 members - March 2022

Survivor Corps

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Long covid is destroying careers, leaving economic distress in its wake - Dec 2021

Washington Post

• "Suffering from debilitating exhaustion and pain for months, patients find themselves on food stamps and Medicaid"
• "Across America, many of the nearly 50 million people infected with the coronavirus continue to suffer from some persistent symptoms, with a smaller subset experiencing such unbearable fatigue and other maladies that they can’t work, forcing them to drop out of the workforce, abandon careers and rack up huge debts."
• "several medical specialists said 750,000 to 1.3 million patients likely remain so sick for extended periods that they can’t return to the workforce full time."

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Costly supplement cocktail for Long-Haul - 2021

https://www.vedicinals.com/
2 of the ingredients are known to activate the Vitamin D Receptor
$172 for 1 month.
Has studies that support it. Have not looked at them

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COVID is probably not the only health problem that results in Long Haul ($1 Billion research) Nov 2021

Could long covid unlock clues to chronic fatigue and other poorly understood conditions? Washington Post

• "...the $1.15 billion investment in research would go beyond long covid to “improve our understanding of other chronic post-viral syndromes and autoimmune diseases, as well as other diseases with similar symptoms.”
• "“How many people have long-term nagging or even disabling symptoms after other viral illnesses, such as flu?”"
• "....Akiko Iwasaki, a Yale immunologist and principal investigator at the Howard Hughes Medical Institute, who lists five hypotheses that she believes could explain the biological underpinning of long covid. Top among them is what she calls a “viral reservoir” of persistent virus or viral remnants in the body that cause chronic inflammation. "

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Long-Haul COVID likely caused by Epstein-Barr virus

Epstein-Barr Virus may cause Long-Haul, CFS, and MS (Vitamin D should help)

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Survey of 5,000 long-haulers- March 2021

https://www.survivorcorps.com/
Some of the columns at the top of one very long table

 Download the PDF from VitaminDWiki

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Long Haul probably decreased if increase Vitamin D getting to cells - on the web

• How to Treat Long-Haul COVID Feb 2021
  • 5 of the 8 treatments suggested are known to increase Vitamin D in the cells
• Resilience and recovery for COVID-19 long haulers June 2021
  • 4 of the 7 treatments suggested are known to increase Vitamin D in the cells

Vitamin D Receptor activation can be increased by any of: Resveratrol,  Omega-3,  Magnesium,  Zinc,   Quercetin,   non-daily Vit D,  Curcumin, intense exercise,   Ginger,   Essential oils, etc  Note: The founder of VitaminDWiki uses 10 of the 13 known VDR activators

The risk of 44 diseases at least double with poor Vitamin D Receptor as of Oct 2019

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More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis - Jan 2021

Prerint doi: https://doi.org/10.1101/2021.01.27.21250617
Sandra Lopez-Leon, Talia Wegman-Ostrosky, Carol Perelman, Rosalinda Sepulveda, Paulina A Rebolledo, Angelica Cuapio, Sonia Villapol

COVID-19, caused by SARS-CoV-2, can involve sequelae and other medical complications that last weeks to months after initial recovery, which has come to be called Long-COVID or COVID long-haulers. This systematic review and meta-analysis aims to identify studies assessing long-term effects of COVID-19 and estimates the prevalence of each symptom, sign, or laboratory parameter of patients at a post-COVID-19 stage. LitCOVID (PubMed and Medline) and Embase were searched by two independent researchers. All articles with original data for detecting long-term COVID-19 published before 1st of January 2021 and with a minimum of 100 patients were included. For effects reported in two or more studies, meta-analyses using a random-effects model were performed using the MetaXL software to estimate the pooled prevalence with 95% CI. Heterogeneity was assessed using I2 statistics. The Preferred Reporting Items for Systematic Reviewers and Meta-analysis (PRISMA) reporting guideline was followed. A total of 18,251 publications were identified, of which 15 met the inclusion criteria.
The prevalence of 55 long-term effects was estimated, 21 meta-analyses were performed, and 47,910 patients were included. The follow-up time ranged from 15 to 110 days post-viral infection. The age of the study participants ranged between 17 and 87 years.
It was estimated that 80% (95% CI 65-92) of the patients that were infected with SARS-CoV-2 developed one or more long-term symptoms.
The five most common symptoms were

• fatigue (58%),
• headache (44%),
• attention disorder (27%),
• hair loss (25%), and
• dyspnea (24%). [[[difficult or labored breathing]

All meta-analyses showed medium (n=2) to high heterogeneity (n=13). In order to have a better understanding, future studies need to stratify by

• sex,
• age,
• previous comorbidities,
• severity of COVID-19 (ranging from asymptomatic to severe), and
• duration of each symptom.

From the clinical perspective, multi-disciplinary teams are crucial to developing preventive measures, rehabilitation techniques, and clinical management strategies with whole-patient perspectives designed to address long COVID-19 care.

 Download the PDF from VitaminDWiki
Clipped from the PDF
The patient follow-up time ranged from 14 days to 110 days.
Six out of the 11 studies included only patients hospitalized for COVID-19.
The rest of the studies mixed mild, moderate, and severe COVID-19 patients.

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Long-haul similar for vaccinated and unvaccinated - Oct 2021

Six-month sequelae of post-vaccination SARS-CoV-2 infection: a retrospective cohort study of 10,024 breakthrough infections

 Download the preprint PDF from VitaminDWiki

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Long-Haul reduced by vaccination: studies range from 0% to 40% - April 2022

Do Vaccines Protect Against Long Covid? New York Times
 Download the preprint PDF from VitaminDWiki

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Those who get COVID-19 after being vaccinated (breakthru) are 1/2 as likely to get long-haul - Sept 2021

New York Times reporting on Lancet

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1/3 of UK Long Haul has lasted more than 1 year - July 2021

Bloomberg

• The U.K. strategy has been sharply criticized. More than 120 scientists co-signed a letter in the Lancet medical journal on July 7, warning that rising infections could leave hundreds of thousands of people with illness and disability “for decades to come.” International experts joined their British counterparts online to sound a further warning on July 16.
• An estimated 962,000 people, or 1.5% of the population, have experienced self-reported long Covid symptoms in the U.K., according to data from the Office for National Statistics published earlier this month. More than a third of those said they’ve suffered for more than a year.

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Long-Haul does not persist in children - Jan 9, 2022

Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study

• 37,522 children aged 0–17 years
• In most children ‘long COVID’ symptoms resolved within 1–5 months.

 Download the PDF from VitaminDWiki

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Long-Haul support groups

Body Politic - COVID-19 SUPPORT GROUP
11,000 members July 2021
There are lots of ways you support our group if you have not been infected with COVID-19, or have completely recovered.

• Request to join our Ally Support Network. We are especially interested in hearing from healthcare providers, wellness practitioners, lawyers, activists, and others with relevant experience in healthcare, chronic illness and disabilities, health justice, and emerging infectious diseases.
• Make a monetary contribution. Our support group is run by a dedicated team of volunteer admins, most of whom are also Covid-19 patients or survivors, or people with other chronic illnesses and disabilities. Your contribution will help us cover operating costs and compensate members of our team for their hard work.
• If you are a researcher interested in studying or collecting data on COVID-19 recoveries, please reach out to patient.research.covid19 at gmail.com. We will review survey submissions and research opportunities to share with the support group as appropriate
• Are you affiliated with a company or non-profit that can support this work in some way? For more information on partnerships, email info at wearebodypolitic.com with a short description of your organization or brand and how you would like to collaborate.

https://www.survivorcorps.com/

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Long haul on the web

• Air trapping common in patients with long COVID March15, 2022
• Long-Haul might be treated by antihistamines - Feb 2022
  • Small observational study of a few patients - symptoms disapeared in 6 months
• Long-Haul appears associated with vagus nerve damageMDEdge Feb 2022
  • "Among 348 patients, about 66% had at least one symptom that suggested vagus nerve dysfunction"
• Post-acute COVID-19 syndrome - April 2021 PDF 100 authors? Table of Contents
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• Long COVID Treatment, Symptoms, and Recovery (Long Haulers) MedCram Video June 6, 2021 starts with the chart at the top of this page
• Podcast: Long COVID Questions AnsweredThe Atlantic May 6, 2021
• A third of Covid-19 survivors suffer 'brain disease,' study shows CNN. April 7, 2021
  • "They found 34% of Covid-19 survivors received a diagnosis for a neurological or psychological condition within six months of their infection, according to the study published Tuesday in the journal Lancet Psychiatry."
  • based on 236 379 survivors of COVID-19   PDF anxiety 17%. mood disorders 14%.
• Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome? - July 2020
  • Download the PDF from VitaminDWiki
• Loss of smell lingers post COVID-19 Feb 24, 2021
  • "More than 50% of health care workers infected with SARS-CoV-2 report that their sense of smell has not returned to normal an average of 5 months post infection"
• Longhaulers good description at COVID.US.ORG
• Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers - JAMA, April 7, 2021
  • The researchers did not observe an increased risk for long-term symptoms after asymptomatic COVID-19
  • PDF Note: Participants had blood sampling performed every 4 months - so their data may have included vitamin D levels
• How Should You Take Care of Yourself After You’ve Had COVID-19? ConsumerLab, April 20, 2021
  • Affected individuals typically report experiencing one or more of the following symptoms: tiredness, difficulty concentrating, headache, loss of smell or taste, dizziness upon standing, heart palpitations, chest pain, shortness of breath, cough, muscle or joint pain, depression, anxiety, and/or fever (CDC, Post-COVID Conditions 4/8/21; Johansson, J Am Coll Cardiol Case Rep 2021; Perlis, JAMA Netw Open 2021; Boscolo-Rizzo, medRxiv 2021 — preprint). A surveillance study in England among 511 people who had recovered from COVID and 1,160 who were not known to have had COVID found that sensory (e.g., loss of taste or smell), neurologic (e.g., difficulty concentrating), and cardiorespiratory symptoms (e.g., chest pain, shortness of breath, palpitations) were more common among those with long COVID than those with no history of infection, while dermatologic (e.g., rashes, hives, or bruising), gastrointestinal (e.g., bloating, nausea, cramps), and mental health symptoms (e.g., depression or anxiety) were not (Amin-Chowdhury, medRxiv 2021 — preprint). The duration of long COVID is still unknown, but at least one study has reported altered taste or smell persisting for up to 12 months (Boscolo-Rizzo, medRxiv 2021 — preprint).
• ConsumerLabs June 2021 - 10% to 50% who recover, up to 76% if had severe COVID-19
• How Long COVID Keeps Us Sick Quanta Mag July 2, 2021
  • "Over 60 clinics have opened throughout the country to treat and study PASC patients, and the National Institutes of Health has received over $1 billion to study the condition. "
• Protocol of treating long-haul with Ivermetin Mercola July 2021
  • I-RECOVER — a long-term management protocol for long-haul syndrome
• Here’s what we know about kids and long covid MIT Review July 13, 2021 PDF
  • "Children who contract covid-19 can have symptoms that persist for weeks or even months, but it’s not clear how frequently this occurs or which kids are at risk."
  • "...researchers in Italy surveyed caregivers of 109 kids who had been infected and found that 42% of the children had at least one symptom two months after their diagnosis. Four months out, the number dropped to 27%. "
  • "But data from the UK’s Office of National Statistics suggest that just 10-13% of kids who test positive for covid have symptoms more for than five weeks."

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See also VitaminDWiki: COVID-19 treated by Vitamin D - studies, reports, videos

As of March 31, 2024, the VitaminDWiki COVID page had:  trial results,   meta-analyses and reviews,   Mortality studies   see related:   Governments,   HealthProblems,   Hospitals,  Dark Skins,   All 26 COVID risk factors are associated with low Vit D,   Fight COVID-19 with 50K Vit D weekly   Vaccines   Take lots of Vitamin D at first signs of COVID   166 COVID Clinical Trials using Vitamin D (Aug 2023)   Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries

 

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Reduce your risk of getting Long-Haul - Take lots of Vitamin D at first signs of COVID

Take lots of Vitamin D at first signs of COVID
If you suspect COVID-19 symptoms, immediately take vitamin D
   (200,000 IU = 10 days sunbathing on a beach)

Emergency Vitamin D

• Quickly energizes the body's immune system
• Vitamin D can fight COVID-19 only if taken soon after infection
• Works equally well with vaccinated (breakthru) and unvaccinated people
• Anticipate that more than half of the people immediately taking Vitamin D will not even test positive for COVID
• Taking Emergency Vitamin D will also extinguish colds, and flu (helps even if the symptoms are not COVID)
• 50,000 IU capsules are widely available on Amazon (50,000 size is rarely available in local stores)
• Vitamin D is like a small fire extinguisher, it can easily put out small blazes but not large ones

# of 50,000 IU capsules if healthy
0-50 lbs 2 caps,   50-150 lbs 3 caps,   150-200 lbs 4 caps,   200-250lbs 5 caps,   >250 lbs 6 caps

# of capsules if suspect low vitamin D
     senior, shut-in, dark skin, immunocompromized, diabetic, or poor gut
0-50 lbs 2 caps,  50-150 lbs 4 caps,   150-200 lbs 6 caps,   200-250lbs 7 caps,   >250 lbs 9 caps

1/2 as many capsules if still have symptoms after 3 days

1/4 as many caps if had close contact with an infected person    or if your vitamin D level is >40 ng
    If need 1/2 capsule: Most 50,000 IU caps can be twisted open. Just use 1/2 of the powder/
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Evidence includes:

1) COVID fought by 50 ng of Vitamin D 7 studies as of Jan 2022

Obese
2) Single 200,000 IU of vitamin D did not benefit the obese in various ways (not a surprise) – RCT Feb 2021
3) Obese need 2X to 3X more vitamin D - Nov 2014

Low weight
4) Quick restoration of vitamin D in children – 10,000 IU per kg loading dose was not enough – Jan 2017
5) Vitamin D loading doses of up to 400,000 IU OK for adolescents – meta-analysis Dec 2014
6) Children in Intensive Care need Vitamin D loading dose of 10000 IU per kg (nearing a consensus) - Oct 2016
    226,000 IU for 50 lbs for children in ICU = maxiumum loading dose.

Virus and COVID
7) Vitamin D can inhibit enveloped virus (e.g. Corona, Herpes, Bird Flu, Epstein, Hepatitis, RSV, etc.) – March 2011
8) Rapid Vitamin D Delivery May Result in Better COVID Outcomes - Dec 9, 2021
9) Large dose of calcifediol or vitamin D up to 15 days before COVID hospitalization reduced death rates (1.5X, 1.3X) – Dec 2021
10) COVID-19 risk reduced by vitamin D supplementation – umbrella review of 7 meta-analysis – Oct 2021
11) French recommended 200,000 IU of Vitamin D to stop COVID-19 - Jan 2021
Response to loading dose
12) Vitamin D loading dose peaks at about day 2

Vitamin D daily from the sun

13) 10,000 to 20,000 IU daily from the sun 2009

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Good Vitamin D Overview - covering 30 topics
VitaminDWiki interview and transcript - Lahore Jan 2022

• There are 30 topics about Vitamin D in the transcript, including many health problems successfully fought by Vitamin D, help before and during pregnancy, problems with vitamin d deficiency, levels to boots the immune system, dosing, and how to buy vitamin D around the world.

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Can get 50,000 IU Vitamin D anywhere on the globe

short URL = https://is.gd/dforcovid

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