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COVID and Magnesium - hypothesis, clinical trials, Long-Haul - Oct 2021


The relevance of magnesium homeostasis in COVID-19

European Journal of Nutrition volume 61, pages 625–636 (2022)
Valentina Trapani, Andrea Rosanoff, Shadi Baniasadi, Mario Barbagallo, Sara Castiglioni, Fernando Guerrero-Romero, Stefano Iotti, André Mazur, Oliver Micke, Guitti Pourdowlat, Giuliana Scarpati, Federica I. Wolf & Jeanette A. Maier

How Magnesium might fight COVID

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Completed trials

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On-going trials (June 2021?)

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Magnesium might help with Long-Haul

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Purpose
In less than one and a half year, the COVID-19 pandemic has nearly brought to a collapse our health care and economic systems. The scientific research community has concentrated all possible efforts to understand the pathogenesis of this complex disease, and several groups have recently emphasized recommendations for nutritional support in COVID-19 patients. In this scoping review, we aim at encouraging a deeper appreciation of magnesium in clinical nutrition, in view of the vital role of magnesium and the numerous links between the pathophysiology of SARS-CoV-2 infection and magnesium-dependent functions.

Methods
By searching PubMed and Google Scholar from 1990 to date, we review existing evidence from experimental and clinical studies on the role of magnesium in chronic non-communicable diseases and infectious diseases, and we focus on recent reports of alterations of magnesium homeostasis in COVID-19 patients and their association with disease outcomes. Importantly, we conduct a census on ongoing clinical trials specifically dedicated to disclosing the role of magnesium in COVID-19.

Results
Despite many methodological limitations, existing data seem to corroborate an association between deranged magnesium homeostasis and COVID-19, and call for further and better studies to explore the prophylactic or therapeutic potential of magnesium supplementation.

Conclusion
We propose to reconsider the relevance of magnesium, frequently overlooked in clinical practice. Therefore, magnesemia should be monitored and, in case of imbalanced magnesium homeostasis, an appropriate nutritional regimen or supplementation might contribute to protect against SARS-CoV-2 infection, reduce severity of COVID-19 symptoms and facilitate the recovery after the acute phase.

 Download the PDF from VitaminDWiki


Study was cited 7 times as of June 2022

Google Scholar

  • Magnesium-to-Calcium Ratio and Mortality from COVID-19 - April 2022 PDF
  • Populations in Low-Magnesium Areas Were Associated with Higher Risk of Infection in COVID-19’s Early Transmission: A Nationwide Retrospective Cohort Study in the United States - PDF
  • Calcium, Magnesium, and Zinc Supplementation during Pregnancy: The Additive Value of Micronutrients on Maternal Immune Response after SARS-CoV-2 Infection - March 2022 PDF
  • Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study - May 2022 PDF

See also Long Covid, Short Magnesium - Chambers April 2022


VitaminDWiki - 24 studies in both categories Virus and Magnesium

This list is automatically updated


VitaminDWiki pages with LONG-HAUL or LONG-COVID in title (40: July 2022)

Items found: 51
Title Modified
Long-COVID fatigue reduced by Vitamin C and l-Arginine in one month– RCT Nov 2022 24 Nov, 2022
Adrenal, Long-COVID and Vitamin D - several studies 31 Oct, 2022
Long Covid, Short Magnesium - Chambers April 2022 30 Oct, 2022
Fatigue and other long-haul problems appear to be associated with low Magnesium - Chambers Oct 2022 30 Oct, 2022
Long-COVID symptoms in 10 Percent of women 3 months after infection (22 countries) – Oct 2022 29 Oct, 2022
Long-COVID is now the biggest COVID concern - many studies 16 Oct, 2022
Epstein-Barr Virus probably causes Long-COVID, CFS, and MS - many studies 02 Oct, 2022
Anti-oxidants and Long-Covid (Mg, Glutamate, Butyrate, etc) – Sept 2022 02 Oct, 2022
Chronic Fatigue Syndrome and long-haul COVID-19 26 Sep, 2022
Over Two Million Americans Aren’t Working Due to Long-COVID - Aug 2022 27 Aug, 2022
Long-COVID: often had not been hospitalized - May 2022 25 Aug, 2022
COVID virus persists in most body tissues (Long-COVID) - 2022 23 Aug, 2022
Long COVID Persists in Almost All Tissues of The Body 23 Aug, 2022
Long-COVID in VitaminDWiki 16 Aug, 2022
LONG-COVID may be permanent in 1 in 200 of people infected – July 2022 06 Aug, 2022
LONG-COVID may be permanent in 1 in 200 of people infected – July 2022 06 Aug, 2022
Long-Haul more prevalent among seniors - June - 2022 26 Jun, 2022
Long-Haul can now be claimed a work disability in the UK – June 2022 24 Jun, 2022
Half as much Long-Haul with Omicron - June 2022 19 Jun, 2022
Half as much Long-Haul with Omicron - June 2022 19 Jun, 2022
COVID Spike persists in Long Haul - June 2022 18 Jun, 2022
COVID Long-Haul prevalence increases with time: 50% at 4 months - meta June 2022 17 Jun, 2022
COVID and Magnesium - hypothesis, clinical trials, Long-Haul - Oct 2021 10 Jun, 2022
Mass disabling events: Polio, WWII, HIV, and COVID Long-Haul - June 2022 06 Jun, 2022
1 in 5 Americans who got COVID had Long-Haul for a while - CDC May 2022 27 May, 2022
Long-Haul COVID after 3 months – only 5 percent had even 30 ng of Vitamin D – April 2022 04 May, 2022
Hypothesis: 2 long-haul COVIDs: had mild symptoms and had needed ICU - April 2022 15 Apr, 2022
COVID Long-Haul at 49 weeks: overactive immune system, type O blood - March 2022 07 Apr, 2022
Children have less severe COVID, but just as much long-haul as adults - April 2022 06 Apr, 2022
Dietary Recommendations for COVID Long-Haul – March 2022 20 Mar, 2022
Mild Long-Haul 4.2 X more likely if type O blood - preprint March 16, 2022 20 Mar, 2022
Long-Haul COVID is somewhat less of a problem if vaccinated – Nov 2021 18 Mar, 2022
COVID Long-Haul NYT - Feb 2022 19 Feb, 2022
COVID Long-Haul fought by probiotics - Jan 2022 29 Jan, 2022
COVID Long-Haul predicted by 4 factors (Epstein-Barr virus, etc) – Jan 24, 2022 26 Jan, 2022
COVID Long-Haul predicted by 4 factors (Epstein-Barr virus, etc) – Jan 24, 2022 26 Jan, 2022
Some COVID-19 infection become COVID Long-Haul - Nov 2020 15 Dec, 2021
Epstein-Barr virus appears to cause Long-Haul and Chronic fatiure Syndrome (Vitamin D might help) 11 Dec, 2021
Long-haul after breakthrough COVID – Nov 2021 11 Dec, 2021
Long-haul, VAERS, Ivermectin, vaccines, etc. Drs. Seheult, Patrick: Video with table of contents - Sept 17, 2021 21 Sep, 2021
Your Brain on Covid-19 Long-Haul, Dr. Galland video and transcript - Aug 1, 2021 07 Aug, 2021
Long-haul COVID-19 blood tests at Mayo include vitamin D (but no results published) – July 2021 20 Jul, 2021
Most people with Long-Haul COVID-19 have low Vitamin D – July 2021 15 Jul, 2021
‘Long haul’ COVID rehab worse than cancer rehab, CDC – July 2021 13 Jul, 2021
Long-Haul COVID-19 occurred to 1 in 20 who had been asymptomatic (a study of 2 million with COVID-19) – June 2021 15 Jun, 2021
COVID-19 Long haul - excellent graph - systematic review May 26, 2021 26 May, 2021
COVID-19 vaccines look good in the short term, but probably not good for the long term 29 Apr, 2021
Long-haul COVID-19 - another hint that Vitamin D should help - Dec 2020 16 Apr, 2021
Probably fewer long-haul COVID-19 problems when rejuvenated immune system (Vitamin D, etc.)– Dec 2020 21 Feb, 2021
Long-haul fatigue, etc. common after viral infections (SARS1,2, MERS, Swine, 1918,...) 21 Feb, 2021
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Created by admin. Last Modification: Monday July 11, 2022 02:36:42 GMT-0000 by admin. (Version 17)

Attached files

ID Name Comment Uploaded Size Downloads
17814 Mg COVID hospital.pdf PDF 2022 admin 10 Jun, 2022 01:46 836.86 Kb 46
17813 Pregnancy Mg COVID.pdf PDF 2022 admin 10 Jun, 2022 01:44 888.28 Kb 50
17812 Low Mg areas_CompressPdf.pdf PDF 2022 admin 10 Jun, 2022 01:40 337.22 Kb 46
17811 CaMg ratio.pdf PDF 2022 admin 10 Jun, 2022 01:36 802.41 Kb 47
17810 Mg Long-Haul.jpg admin 09 Jun, 2022 23:56 73.03 Kb 115
17809 Mg ongoing trials.jpg admin 09 Jun, 2022 23:55 209.70 Kb 109
17808 Existing trials T1.jpg admin 09 Jun, 2022 23:55 99.48 Kb 111
17807 Mg fig 1.jpg admin 09 Jun, 2022 23:54 40.75 Kb 119
17806 Mg COVID March 2022.pdf admin 09 Jun, 2022 23:49 593.53 Kb 48
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