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Low Vitamin D etc. more than 3 months after COVID hospitalization – Sept 2021

Long-term clinical and biochemical residue after COVID-19 recovery

Egyptian Liver Journal volume 11, https://doi.org/10.1186/s43066-021-00144-1
Mohammed Ali Gameil, Rehab Elsayed Marzouk, Ahmed Hassan Elsebaie & Salah Eldeen Rozaik

Blood measured 3 to 6+ months after PCR positive test

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Healthy vs months after COVID-19 Recovery

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 Download the PDF from VitaminDWiki

Background
The long-term health consequences of coronavirus disease 2019 (COVID-19) are still unclear. The majority of previous trials addressed the post-COVID-19 symptoms through comprehensive medical questionnaires for relatively short periods after recovery. We tried to detect the potential pathological clinical signs and biochemical residue which persist for more than 3 months after the negative real-time polymerase chain reaction (RT-PCR) test of SARS-CoV-2.

Results
Among 120 COVID-19 survivors of mean age 38.29 and 55.6% male proportion,

  • systolic blood pressure was significantly elevated (P=0.001).
  • Erythrocyte sedimentation rate (ESR),

(C-reactive protein (CRP),

  • D-dimer showed higher values in COVID-19 survivors (P< 0.001).
  • Alanine aminotransferase (ALT),
  • aspartate aminotransferase (AST),
  • gamma-glutamyl trans-peptidase (GGT), and
  • alkaline phosphatase (ALP) were significantly elevated in contrast to
  • serum albumin that was reduced in COVID-19 survivors (P ≤0.001).
  • Serum lipase,
  • amylase and
  • albuminuria

were higher in COVID-19 survivors (P ≤0.001).
Regression analysis (AOR, 95% CI) showed that ESR (P = 0.014), haemoglobin concentration (P = 0.039), serum lipase (P= 0.018), blood urea nitrogen (P= 0.003), albuminuria (P= 0.046), 25(OH) vitamin D (P= 0.002), and serum uric acid (P= 0.005) were the significant predictors of COVID-19 survivors (94.8% an overall prediction).

Conclusion
COVID-19 survivors experienced residual significant clinical and biochemical alterations that necessitate comprehensive medical care and close follow-up for longer periods.


Created by admin. Last Modification: Monday November 15, 2021 20:39:10 GMT-0000 by admin. (Version 6)

Attached files

ID Name Comment Uploaded Size Downloads
16599 Univariant.jpg admin 15 Nov, 2021 20:23 113.14 Kb 75
16598 After COVID case-control.jpg admin 15 Nov, 2021 20:22 118.85 Kb 103
16597 Months.jpg admin 15 Nov, 2021 20:22 15.41 Kb 71
16596 Long-term clinical and biochemical residue after COVID.pdf PDF 2021 admin 15 Nov, 2021 20:21 651.93 Kb 10
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