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Preterm Births reduced by Omega-3, Zinc, and Vitamin D – Aug 2019


Preterm Birth: A Narrative Review of the Current Evidence on Nutritional and Bioactive Solutions for Risk Reduction.

Nutrients. 2019 Aug 6;11(8). pii: E1811. doi: 10.3390/nu11081811.
Samuel TM1, Sakwinska O1, Makinen K1, Burdge GC2, Godfrey KM3, Silva-Zolezzi I4.

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Preterm birth (PTB) (<37 weeks of gestation) is the leading cause of newborn death and a risk factor for short and long-term adverse health outcomes. Most cases are of unknown cause. Although the mechanisms triggering PTB remain unclear, an inappropriate increase in net inflammatory load seems to be key. To date, interventions that reduce the risk of PTB are effective only in specific groups of women, probably due to the heterogeneity of its etiopathogenesis. Use of progesterone is the most effective, but only in singleton pregnancies with history of PTB. Thus, primary prevention is greatly needed and nutritional and bioactive solutions are a promising alternative. Among these, docosahexaenoic acid (DHA) is the most promising to reduce the risk for early PTB. Other potential nutrient interventions include the administration of zinc (possibly limited to populations with low nutritional status or poor zinc status) and vitamin D; additional preliminary evidence exists for vitamin A, calcium, iron, folic acid, combined iron-folate, magnesium, multiple micronutrients, and probiotics. Considering the public health relevance of PTB, promising interventions should be studied in large and well-designed clinical trials. The objective of this review is to describe, summarize, and discuss the existing evidence on nutritional and bioactive solutions for reducing the risk of PTB.


VitaminDWiki Pregnancy pages with PRETERM of PRE-TERM in title (61 as of May 2022)

This list is automatically updated

Items found: 62
Title Modified
4.4 X more likely to have a preterm birth if low vitamin D while pregnant - May 2022 23 May, 2022
Arab preterm infants often have less than 10 ng of vitamin D - 2010 15 May, 2022
Preterm birth interventions – 4 studies found possible vitamin D benefit – Cochrane – Nov 2018 15 May, 2022
Preterm birth might be prevented by Vitamin D, Omega-3, etc. (International survey) – Jan 2019 15 May, 2022
Preterm Births - promising preventions – anti-oxidants, Vitamin D, Omega-3, Zinc, etc. – Jan 2019 15 May, 2022
Preterm birth chance reduced – with 17P or Vitamin D – June 2015 15 May, 2022
Preterm birth reduction by nutrients - Vitamin D is the best, Omega-3 is next best – May 2022 15 May, 2022
Omega-3 supplementation reduced preterm birth rate by 4X – RCT July 2020 10 Apr, 2022
Preterm birth rate of pregnant smokers cut in half if take Omega-3 – RCT May 2017 20 Feb, 2022
Preterm birth varies with season: 25 percent more likely if conception in autumn – Feb 2022 04 Feb, 2022
Pre-term birth rate cut in half with 1000 milligrams of Omega-3 (if initially low) – RCT May 2021 04 Jun, 2021
Preterm birth risk increased 16 pcnt if heat wave (perhaps outside less) - Nov 2020 16 Nov, 2020
Preterm birth associated with many genes, including the Vitamin D Receptor again – Jan 2020 30 Jan, 2020
Preterm birth 8X more likely if poor Vitamin D Receptor – Dec 2019 31 Dec, 2019
8 percent fewer preterm births if adequate Selenium from food – Aug 2019 24 Dec, 2019
Pregnant women in Australia to take Omega-3 when told of reduction in preterm births – Dec 2019 19 Nov, 2019
Preterm birth 9 X more likely if fetus had a poor Vitamin D Receptor and previous miscarriage – Aug 2017 12 Nov, 2019
Preterm birth rate not vary with vitamin D level (when all are less than 30 ng) – Oct 2019 17 Oct, 2019
Extreme preterm infants helped somewhat by 800 IU of vitamin D – RCT Jan 2018 01 Oct, 2019
Preterm Births reduced by Omega-3, Zinc, and Vitamin D – Aug 2019 09 Aug, 2019
Preterm birth increases risk of heart disease by 1.5 X by age 40 – June 2019 06 Aug, 2019
Preterm Births decreased by Omega-3 (analysis of 184 countries) – April 2019 27 Apr, 2019
Preterm birth 3X more likely if low vitamin D – Oct 2018 07 Feb, 2019
Omega-3 index of 5 greatly decreases the risk of an early preterm birth – Dec 2018 04 Jan, 2019
Preterm birth cost for employers approximately 50,000 dollars – Oct 2017 28 Sep, 2018
Preterm births 12 X more likely if poor Vitamin D Receptor (white infants in Italy) – meta-analysis Aug 2018 27 Aug, 2018
Third trimester Vitamin D levels were lower if pre-term labor was expected – March 2018 24 Mar, 2018
Preterm birth 4X more likely if very low Vitamin D (Chinese) - Feb 2018 28 Feb, 2018
Preterm birth rates increased in 15 European countries – Oct 2013 23 Dec, 2017
Vitamin D intervention reduces preterm births and low birth weight by 60 percent – Cochrane Reviews – Nov 2017 07 Dec, 2017
Preterm birth rate increased 60 percent in 50 years (US) 26 Nov, 2017
Preterm births are VERY costly – Feb 2017 26 Nov, 2017
Preterm births strongly related to Vitamin D, Vitamin D Receptor, Iodine, Omega-3, etc 13 Nov, 2017
Vitamin D Receptor is associated with preeclampsia, gestational diabetes and preterm birth – Nov 2017 10 Nov, 2017
Preterm birth trend toward 2.5 X more likely if less than 10 ng of Vitamin D – Aug 2017 26 Aug, 2017
Preterm birth rate reduced by vitamin D – 78 percent if non-white, 39 percent if white – July 2017 27 Jul, 2017
Preterm birth more likely if dark skinned and low vitamin D (not white-skinned) – April 2017 06 Jul, 2017
Risk of preterm birth twice as likely when less than 10 ng of vitamin D – Nov 2016 13 Apr, 2017
Preterm labor 20 times more likely if low vitamin D, etc. (India) – Feb 2017 08 Mar, 2017
Preterm birth rate reduced by 43 percent with adequate Vitamin D supplementation – meta-analysis Feb 2017 02 Mar, 2017
Pre-term birth - many of risk factors are associated with low vitamin D 27 Feb, 2017
Preterm birth rate reduced 57 percent by Vitamin D – Nov 2015 23 Jan, 2017
Vitamin D Webinar - cost of pre-term birth etc- Baggerly Nov 2013 11 Dec, 2016
Preterm birth extended by 2 weeks with Omega-3 – Meta-analysis Nov 2015 10 Dec, 2016
Omega-3 supplementation during pregnancy reduce early preterm births (save 1500 USD per child) – Aug 2016 12 Oct, 2016
Zinc helps pregnancies – 14 percent fewer preterm births, etc. – Cochrane RCT Feb 2015 14 Jun, 2016
Preterm birth has become the leading cause of infant mortality (vitamin D not mentioned) – JAMA June 2016 07 Jun, 2016
Preterm birth 30 percent more likely if low vitamin D – meta-analysis May 2016 20 May, 2016
Asthmatic pregnant women had 30 percent more preterm births if air pollution (vitamin D not mentioned) – March 2016 09 Mar, 2016
Omega-3 helps pregnancy in many ways: preterm 26 percent less likely etc – review July 2012 08 Sep, 2015
Extreme preterm survival 30 percent less likely if little sunshine 23-28 weeks – June 2015 05 Sep, 2015
Magnesium (Sulfate) reduces risk of cerebral palsy for those at risk of pre-term births – Dec 2013 18 Aug, 2015
Respiratory distress after preterm birth is more likely if low vitamin D – review April 2015 05 Aug, 2015
Pre-term births reduced in half if 40 ng of vitamin D in 3rd trimester – Nov 2014 15 Mar, 2015
Chance of preterm birth is strongly associated with low vitamin D – Feb 2015 05 Feb, 2015
The more preterm the birth, the lower the vitamin D level (both mothers and infants) – Feb 2014 05 Feb, 2015
Preterm infants more likely to have vitamin D levels below 20 ng – Feb 2014 05 Feb, 2015
Decreased risk of preterm birth if have more than 36 ng of vitamin D – Jan 2015 09 Jan, 2015
Pre-term birth 3X more likely and C-section 4X if less than 20 ng of vitamin D – May 2012 13 Feb, 2014
Recurrent pre term birth and low vitamin D – Dec 2012 23 Jan, 2013
Blacks have more pre-term births due to low nutrients such as vitamin D – Sept 2011 14 Sep, 2011
Pre-term birth not associated with first tri-mester vitamin D – April 2011 21 Apr, 2011

VitaminDWiki Items in both categories Pregnancy and Zinc


Created by admin. Last Modification: Sunday May 15, 2022 14:43:56 GMT-0000 by admin. (Version 8)

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12449 PTB 3.pdf PDF 2019 admin 09 Aug, 2019 16:33 667.66 Kb 345
12448 PTB reduction - Table 3.jpg admin 09 Aug, 2019 16:30 124.82 Kb 326
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