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Preterm birth might be prevented by Vitamin D, Omega-3, etc. (International survey) – Jan 2019

Research prioritization of interventions for the primary prevention of preterm birth: An international survey.

Eur J Obstet Gynecol Reprod Biol. 2019 Jan 25. pii: S0301-2115(19)30048-X. doi: 10.1016/j.ejogrb.2019.01.021.
Allotey J1, Matei A2, Husain S3, Newton S4, Dodds J5, Armson AB2, Khan KS5, Vogel JP6.

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5 (1.0) Affordability to women The intervention will be affordable to women
5 (1.0)Affordability to HCP The intervention will be affordable to health careproviders
5 (1.0)Acceptability to women The intervention will be acceptable to women
5 (0) Acceptability to HCP The intervention will be acceptable to health careproviders
5 (1.0) Implementation The intervention can be implemented
5 (1.0)Sustainability The intervention can be sustained in the long-term
4 (2.0)Equity The intervention will reach the most vulnerablegroups and reduce health inequity
4 (2.0)Effectiveness of an RCT An RCT on this intervention is likely to demonstrate desirable or beneficial effects
5 (1.0) Feasibility of an RCT An RCT on this intervention would be feasible
5 (1.0Summary Score

Vitamin D, Omega-3, etc
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OBJECTIVE:
To identify research priorities of interventions for the primary prevention of preterm birth (PTB), by conducting an international stakeholder survey.

STUDY DESIGN:
A prospective cross-sectional online survey was conducted in November 2016. Fifteen interventions to prevent spontaneous PTB were identified and ranked by stakeholders (n = 159) in the field of maternal and perinatal health research, using nine equally weighted criteria. Medians and interquartile ranges (IQRs) were calculated and the interventions ranked accordingly.

RESULTS:
Respondents to the survey were from 46 different countries, mostly from low and middle-income countries (62%, 99/159) and were mainly clinicians (80%, 127/159). Of the fifteen interventions ranked, the following five were identified as research priorities in the primary prevention of PTB: dietary counselling and nutritional education, risk scoring, vitamin D supplementation, exercise and antioxidant supplementation.

CONCLUSION:
We have identified research priorities of interventions to prevent spontaneous PTB through a global stakeholder survey. The interventions prioritized in this exercise can be used by researchers, grant funding bodies and research-policy decision makers to inform calls on future clinical trials or individual patient data meta-analyses on the primary prevention of PTB.



Attached files

ID Name Comment Uploaded Size Downloads
11335 Preterm all.jpg admin 04 Feb, 2019 17:32 156.79 Kb 23
11334 Preterm Vitamin D.jpg admin 04 Feb, 2019 17:32 18.28 Kb 17
11333 Preterm interventions Sci-Hub.pdf admin 04 Feb, 2019 17:32 641.57 Kb 7
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