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Preterm infants, kidney, rickets and vitamin D intake: is it time for rewriting the history – Aug 2014

Their title, not mine

Archives of Gynecology and Obstetrics – Aug 2014
Raffaella Mormile, Vassilios Fanos, Giorgio Vittori
1 Division of Pediatrics and Neonatology, Moscati Hospital, Via A. Gramsci, 3, 81031, Aversa, Italy, raffaellamormile at alice.it.

Free excerpt: Publisher wants $45 for PDF

Great advances in neonatal intensive care have improved survival rates of infants who once had little chance for survival such as preterm babies [1, 2]. Organ system immaturity in preterm infants is connected with long term complications that have both clinical and public health importance [1]. Severe hypoxia occurs in most preterm infants leading to cell death which may be necrotic or apoptotic [1]. Significant elevation of apoptotic activity has been shown to play a prominent role in the pathogenesis of several diseases associated with prematurity such as renal dysfunction [1]. In the kidneys of preterm infants, apoptosis has been described in tubular epithelial cells [1]. Renal tubular cell apoptosis has been shown to play a critical role in the pathogenesis of acute renal failure [3]. The consequences of premature birth or low birth weight on nephrogenesis, final nephron number and long-term kidney function are still not well defined [2].The kidney of low birth weight preterm infan . . .


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VitaminDWiki believes that the history does not have to be re-written.

However, the current recommendations need to be increased to face the reality that virtually EVERYONE now has less vitamin D.
Reasons for Vitamin D deficiency 34 reasons as of 2014
Less Sun Less D Less Health

See also VitaminDWiki

IU Cumulative Benefit Blood level CofactorsCalcium $*/month
200 Better bones for mom
with 600 mg of Calcium
6 ng/ml increase Not needed No effect $0.10
400 Less Rickets (but not zero with 400 IU)
3X less adolescent Schizophrenia
Fewer child seizures
20-30 ng/ml Not needed No effect $0.20
2000 2X More likely to get pregnant naturally/IVF
2X Fewer dental problems with pregnancy
8X less diabetes
4X fewer C-sections (>37 ng)
4X less preeclampsia (40 ng vs 10 ng)
5X less child asthma
2X fewer language problems age 5
42 ng/ml Desirable < 750 mg $1
4000 2X fewer pregnancy complications
2X fewer pre-term births
49 ng/ml Should have
< 750 mg $3
6000 Probable: larger benefits for above items
Just enough D for breastfed infant
More maternal and infant weight
Should have
< 750 mg $4

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