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Preterm birth trend toward 2.5 X more likely if less than 10 ng of Vitamin D – Aug 2017

Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

Int J Occup Med Environ Health 2017;30(6) DOI: https://doi.org/10.13075/ijomeh.1896.01146
Marta Baczyńska-Strzecha 1 , Jarosław Kalinka 1
Medical University in Lodz, Łódź, Poland (Department of Perinatology, 1st Chair of Obstetrics and Gynecology)

See also VitaminDWiki

Healthy pregnancies need lots of vitamin D has the following summary

0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

 Download the PDF from VitaminDWiki



Objectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland.

Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term.

Results: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094).

Conclusions: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth.

Created by admin. Last Modification: Saturday August 26, 2017 14:20:14 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
8351 Preterm Poland Table 1.jpg admin 26 Aug, 2017 14:18 109.50 Kb 378
8350 preterm births Poland.pdf PDF 2017 admin 26 Aug, 2017 14:03 274.36 Kb 517