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Preterm birth trend toward 2.5 X more likely if less than 10 ng of Vitamin D – Aug 2017

Assessment of correlation between vitamin D level and prevalence of preterm births in the population of pregnant women in Poland

Int J Occup Med Environ Health 2017;30(6) DOI: https://doi.org/10.13075/ijomeh.1896.01146
Marta Baczyńska-Strzecha 1 , Jarosław Kalinka 1
Medical University in Lodz, Łódź, Poland (Department of Perinatology, 1st Chair of Obstetrics and Gynecology)

See also VitaminDWiki

Healthy pregnancies need lots of vitamin D has the following summary

Problem
Vit. D
Reduces
Evidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial


 Download the PDF from VitaminDWiki

Table1

Image


Objectives: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland.

Material and Methods: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term.

Results: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% – in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86–7.15, p = 0.094).

Conclusions: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth.


Created by admin. Last Modification: Saturday August 26, 2017 14:20:14 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
8351 Preterm Poland Table 1.jpg admin 26 Aug, 2017 109.50 Kb 448
8350 preterm births Poland.pdf admin 26 Aug, 2017 274.36 Kb 579