Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes - Jan 2021

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Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes

Nutrients 2021, 13, 320. https://doi.org/10.3390/nu13020320
Gabriele Piuri1,+, Monica Zocchi h+ , 1 , 2 ,
Gian Vincenzo Zuccotti 1,3 , Luciano Pinotti 2 , Jeanette A. Maier1 and Roberta Cazzola 1,*0
Department of Biomedical and Clinical Sciences "L. Sacco", Università di Milano, 20157 Milan, Italy; gabriele.piuri at unimi.it (G.P.); monica.zocchi at unimi.it (M.Z.); matteo.dellaporta at unimi.it (M.D.P.); valentina.ficara at unimi.t (V.F.); gianvincenzo.zuccotti at unimi.it (G.V.Z.); jeanette.maier at unimi.it (J.A.M.)
Department of Health, Animal Science and Food Safety, Università di Milano, 20133 Milan, Italy; michele.manoni at unimi.it (M.M.); luciano.pinotti at unimi.it (L.P.)
Department of Pediatrics, Ospedale dei Bambini, 2154 Milan, Italy * Correspondence: roberta.cazzola at unimi.it

+ These authors contributed equally to this work.

Chart of interactions

Magneium and Insulin

Magnesium Clinical Trials

Magnesium (Mg2+) deficiency is probably the most underestimated electrolyte imbalance in Western countries. It is frequent in obese patients, subjects with type-2 diabetes and metabolic syndrome, both in adulthood and in childhood. This narrative review aims to offer insights into the pathophysiological mechanisms linking Mg2+ deficiency with obesity and the risk of developing metabolic syndrome and type 2 diabetes. Literature highlights critical issues about the treatment of Mg2+ deficiency, such as the lack of a clear definition of Mg2+ nutritional status, the use of different Mg2+ salts and dosage and the different duration of the Mg2+ supplementation. Despite the lack of agreement, an appropriate dietary pattern, including the right intake of Mg2+, improves metabolic syndrome by reducing blood pressure, hyperglycemia, and hypertriglyceridemia. This occurs through the modulation of gene expression and proteomic profile as well as through a positive influence on the composition of the intestinal microbiota and the metabolism of vitamins B1 and D.
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VitaminDWiki - 11 studies in both categories Magnesium and Obesity

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VitaminDWiki - 9 studies in both categories Magnesium and Metabolic Syndrome

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VitaminDWiki - 27 studies in both categories Magnesium and Diabetes

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VitaminDWiki - Magnesium and Vitamin D category contains

338 items in category, see also

• Overview Magnesium and vitamin D
• Magnesium deficiency – causes and symptoms – May 2016
• Vitamins and Metals needed by the Immune System – Jan 2020
• Magnesium: intake decreased, difficult to measure in body – Sept 2018
• Magnesium deficiency estimated by just 6 Yes No questions - Dec 2019
• Magnesium fights diabetes (yet again)– meta-analysis Nov 20218
• Intracellular Magnesium and Vitamin D - a few studies
• Magnesium in Healthcare (Rickets, Stones, Pregnancy, Depression, etc.) with level of evidence – Sept 2017
• Magnesium is great for health, topical much faster than oral, MgCl2 is the best – 2019
• Magnesium is important for health but levels are low – July 2018
• How to get lots of Magnesium – especially needed for Coimbra MS and Autoimmune Protocol
• COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022
• Magnesium etc. reduced in crops (must supplement) – 2009

Mg and Vitamin D

• Intracellular Magnesium and Vitamin D - a few studies
• Vitamin D and Magnesium need each other - many studies
• Why Vitamin D is Useless without This Critical Nutrient (Magnesium) - Jan 2019
• 500 mg of Magnesium for 8 weeks increased Vitamin D by 4 ng – July 2020
• Magnesium and Vitamin D - pre-colon cancer – RCT Dec 2018
• Magnesium is vital to Vitamin D in 4 places (maybe 8) – March 2018
• Magnesium and Vitamin D – recent deficiencies, needed, synergistic - good overview 2017
• Vitamin D Cofactors in a nutshell
• Magnesium and Vitamin D - similar, different and synergistic

Dr. Dean

• Some Podcasts by Dr. C Dean – Magnesium, Vitamin D, Iodine, etc.
• Magnesium and the body - depletion and reduced intake - Dean Oct 2019
• Magnesium, Vitamin D, Omega-3, TSH - importance and testing - Dean and Baggerly - Oct 2019

Number of studies in both of the categories of Magnesium and:

Bone 15,  Cardiovascular 17,   Diabetes 27. Depression 14,  Obesity 11,   Omega-3 33,  Zinc 23,  Pregnancy 10,  Headache 10,   Virus 25,   Calcium 26   Virus 25   Mortality 8   Hypertension 11   Inflammation 3   Pain 7 etc.

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20 most-recently changed items in Magnesium Category

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