- Magnesium status modulating the effect of serum vitamin D levels on retinopathy: National Health and Nutrition Examination Survey 2005 to 2008
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32 studies in both categories Diabetes and Magnesium - VitaminDWiki -
8 studies in both categories Diabetes and Vision
Magnesium status modulating the effect of serum vitamin D levels on retinopathy: National Health and Nutrition Examination Survey 2005 to 2008
Front Nutr. 2024 Jun 4:11:1408497. doi: 10.3389/fnut.2024.1408497
Lei Xu 1, Penghua Yuan 2, Wanrong Liu 1, Linlin Liu 1, Xiongfeng Li 1, Lianfeng Xie 1Aim: Magnesium levels may influence the effect of vitamin D levels on the body. This study aimed to assess the combined effect of magnesium status as reflected by magnesium depletion score (MDS) and vitamin D status on the risk of retinopathy.
Methods: This cross-sectional study included participants aged 40 years and older with complete information on vitamin D, MDS, and retinopathy assessment from the 2005-2008 National Health and Nutrition Examination Survey (NHANES). Logistic regression analysis was utilized to analyze the relationship of MDS and vitamin D with retinopathy and expressed as odds ratio (OR) and 95% confidence interval (CI).
Results: Of these 4,953 participants included, 602 (9.53%) participants had retinopathy.
Serum vitamin D levels ≤30 nmol/L (vs. >30 nmol/L) (OR = 1.38, 95%CI: 1.05-1.81) and MDS >2 points (vs. ≤2 points) (OR = 1.47, 95%CI: 1.01-2.16) were associated with higher odds of retinopathy.
There was an interaction between MDS and vitamin D on the increased odds of retinopathy (OR = 2.29, 95%CI: 1.12-4.68, P interaction = 0.025). In different MDS groups, serum vitamin D levels ≤30 nmol/L increased the odds of retinopathy only in the MDS >2 group (OR = 2.90, 95%CI: 1.16-7.24), but not in the MDS ≤2 group (p = 0.293).
Subgroups analyses demonstrated that the interaction between MDS and serum vitamin D on retinopathy was observed- in males (OR = 6.88, 95%CI: 1.41-33.66, P interaction = 0.019),
- people with diabetes (OR = 3.43, 95%CI: 1.78-6.63, P interaction < 0.001), and
- people with body mass index (BMI) ≥25 kg/m2 (OR = 2.46, 95%CI: 1.11-5.44, P interaction = 0.028).
Conclusion: Magnesium plays a moderating role in the relationship between serum vitamin D and retinopathy. The protective effect of vitamin D against retinopathy was primarily present among those with inadequate magnesium levels.
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32 studies in both categories Diabetes and Magnesium This list is automatically updated
- Vitamin D, minerals (Mg, Ca, K, Phosphate, Na, Fe, Zn, Cl, Se) and health – 15 studies 2024
- Diabetics more likely to die if low Magnesium (MDS) - Jan 2025
- Vitamin D Roles - more than just help the immune system
- Retinopathy in males 6.9 X more likely if low vitamin D and low Magnesium - June 2024
- Magnesium Depletion Score predicts increased risk of various health problems
- High fluoride in water: 5X more likely to be Vitamin D deficient – Jan 2023
- Diabetes, Metabolic Syndrome and Magnesium - many studies
- More Magnesium needed to decrease diabetes, cardio, HT (body weight has increased) - March 2021
- Treating pre-diabetes with Magnesium Chloride should be cost effective – June 2022
- Reduced Magnesium is associated with reduced health (Diabetes in this case) - April 2022
- Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes - Jan 2021
- The Role of Magnesium in the Pathogenesis of Metabolic Disorders – April 2022
- Magnesium fights diabetes (yet again)– meta-analysis Nov 2021
- Excessive insulin decreases vitamin D in 4 ways – problems for diabetic COVID-19 – Dec 2020
- Low Magnesium associated with diabetes, etc. – meta-analysis 2016
- Low Level Laser Therapy greatly increased Vitamin D and Magnesium (for diabetics with nephropathy) – March 2019
- Young Diabetics had 3.8 X higher risk of Parkinson’s (perhaps low Mg or low Vitamin D)– June 2018
- Cardiometaboic problems decreased with increased Vitamin D, unless low Magnesium – Aug 2017
- Diabetes 29 % less likely if consume lots of Magnesium and cereal fiber (surveys of 200,000 people) – Oct 2017
- Magnesium is associated with prevention and treatment of Diabetes – Meta-analysis Aug 2016
- Type 2 diabetes associated with low Magnesium
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
- Prediabetes reduced in half by those getting Magnesium Chloride – RCT April 2015
- Type II Diabetes might be prevented and treated with Magnesium – Review Feb 2015
- Diabetes decreased with 300 mg of Mg (Mg Sulfate) – RCT July 2014
- Daily Magnesium improved all aspects of metabolic profile – RCT July 2014
- Diabetes and low Magnesium - Mercola 2014 - 2019
- Diabetics have problems with low Magnesium, especially if taking statins – Aug 2013
- Low Magnesium and type II diabetes – June 2012
- Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
- Reduced chance of diabetes 46 percent with Magnesium - Oct 2010
VitaminDWiki -
8 studies in both categories Diabetes and Vision This list is automatically updated
- Retinopathy in males 6.9 X more likely if low vitamin D and low Magnesium - June 2024
- Diabetic Retinopathy associated with low Vitamin D - many studies
- Diabetic Retinopathy twice as likely if a T2 Diabetic has low level of vitamin D – meta-analysis March 2017
- Diabetic Retinopathy 2 X more likely if poor Vitamin D Receptor – meta-analysis Nov 2016
- Diabetic Retinopathy 27 percent more likely if low vitamin D – meta-analysis May 2016
- Diabetic Neuropathy sometimes can be reversed by vitamin D
- Worse diabetic vision is associated with low vitamin D or high PTH - Nov 2012
- Diabetics have more retina problems as they have less vitamin D – Sept 2011
Retinopathy in males 6.9 X more likely if low vitamin D and low Magnesium - June 2024Printer Friendly Follow this page for updates361 visitors, last modified 27 Jun, 2024, This page is in the following categories (# of items in each category) - VitaminDWiki -