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The Role of Magnesium in the Pathogenesis of Metabolic Disorders – April 2022


The Role of Magnesium in the Pathogenesis of Metabolic Disorders

Nutrients 2022, 14(9), 1714; https://doi.org/10.3390/nu14091714
by Marta Pelczyńska *ORCID,Małgorzata MoszakORCID and Paweł BogdańskiORCID
Department of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznań University of Medical Sciences, 84 Szamarzewskiego Street, 60-569 Poznań, Poland

Magnesium (Mg) is an essential nutrient for maintaining vital physiological functions. It is involved in many fundamental processes, and Mg deficiency is often correlated with negative health outcomes. On the one hand, most western civilizations consume less than the recommended daily allowance of Mg. On the other hand, a growing body of evidence has indicated that chronic hypomagnesemia may be implicated in the pathogenesis of various metabolic disorders such as

  • overweight and obesity,
  • insulin resistance (IR) and type 2 diabetes mellitus (T2DM),
  • hypertension (HTN),
  • changes in lipid metabolism, and
  • low-grade inflammation.

High Mg intake with diet and/or supplementation seems to prevent chronic metabolic complications. The protective action of Mg may include limiting the adipose tissue accumulation, improving glucose and insulin metabolism, enhancing endothelium-dependent vasodilation, normalizing lipid profile, and attenuating inflammatory processes. Thus, it currently seems that Mg plays an important role in developing metabolic disorders associated with obesity, although more randomized controlled trials (RCTs) evaluating Mg supplementation strategies are needed. This work represents a review and synthesis of recent data on the role of Mg in the pathogenesis of metabolic disorders.

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Magnesium: Obesity + Hypertension

Meta-analyses in study
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VitaminDWiki - Magnesium and Obesity
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VitaminDWiki - Magnesium and Hypertension
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Magnesium: and Diabetes

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VitaminDWiki - Magnesium and Diabetes
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Magnesium and High Cholesterol Meta-analyses

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Magensium and Inflammation

Chart Mg and Low-grade Inflammation
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VitaminDWiki Magnesium and Inflammation
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VitaminDWiki - Magnesium and Vitamin D contains

320 items in category, see also

Mg and Vitamin D

Dr. Dean

Number of studies in both of the categories of Magnesium and:

Bone 15,  Cardiovascular 17,   Diabetes 25. Depression 14,  Obesity 11,   Omega-3 30,  Zinc 21,  Pregnancy 9,  Headache 10,   Virus 22,   Calcium 24   Virus 22   Mortality 7   Hypertension 10   Inflammation 3

Magnesium associations in VitaminDWiki (More than 4)

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Summary of Associations

Associated category Associations
7
24
7
6
7
22
17
8
23
10
33
30
21
25
11
8
11
15
10
5
8
8
6
13
9
14
5
5
8
8
5

Results

7 pages in both categories: Vitamin D and Magnesium + Pain - chronic

24 pages in both categories: Vitamin D and Magnesium + Vitamin D and Calcium

7 pages in both categories: Vitamin D and Magnesium + Vitamin D and Boron

6 pages in both categories: Vitamin D and Magnesium + Vitamin C

7 pages in both categories: Vitamin D and Magnesium + Books, videos on Vitamin D

22 pages in both categories: Vitamin D and Magnesium + Virus

17 pages in both categories: Vitamin D and Magnesium + Cardiovascular

8 pages in both categories: Vitamin D and Magnesium + Intervention

23 pages in both categories: Vitamin D and Magnesium + Vitamin D and Vitamin K

10 pages in both categories: Vitamin D and Magnesium + Headache

33 pages in both categories: Vitamin D and Magnesium + Top news

30 pages in both categories: Vitamin D and Magnesium + Vitamin D and Omega-3

21 pages in both categories: Vitamin D and Magnesium + Zinc

25 pages in both categories: Vitamin D and Magnesium + Diabetes

11 pages in both categories: Vitamin D and Magnesium + Obesity

8 pages in both categories: Vitamin D and Magnesium + Metabolic Syndrome

11 pages in both categories: Vitamin D and Magnesium + Vitamin B12

15 pages in both categories: Vitamin D and Magnesium + Bone - Health

10 pages in both categories: Vitamin D and Magnesium + Hypertension

5 pages in both categories: Vitamin D and Magnesium + Kidney

8 pages in both categories: Vitamin D and Magnesium + Mortality and D

8 pages in both categories: Vitamin D and Magnesium + Deficiency of Vitamin D

6 pages in both categories: Vitamin D and Magnesium + Cognitive

13 pages in both categories: Vitamin D and Magnesium + Vitamin D and Iron

9 pages in both categories: Vitamin D and Magnesium + Pregnancy

14 pages in both categories: Vitamin D and Magnesium + Depression

5 pages in both categories: Vitamin D and Magnesium + Iodine

5 pages in both categories: Vitamin D and Magnesium + Interactions with Vitamin D

8 pages in both categories: Vitamin D and Magnesium + Supplement

8 pages in both categories: Vitamin D and Magnesium + Seniors

5 pages in both categories: Vitamin D and Magnesium + Trauma and surgery


Created by admin. Last Modification: Monday April 25, 2022 16:41:39 GMT-0000 by admin. (Version 13)

Attached files

ID Name Comment Uploaded Size Downloads
17482 Low-grade inflammation.jpg admin 23 Apr, 2022 14:58 184.44 Kb 120
17481 High Cholesterol.jpg admin 23 Apr, 2022 14:58 283.04 Kb 125
17480 Diabetes.jpg admin 23 Apr, 2022 14:57 344.18 Kb 125
17479 Obesity, Hypertension.jpg admin 23 Apr, 2022 14:57 290.15 Kb 129
17478 Mg Metabolic.jpg admin 23 Apr, 2022 14:56 207.72 Kb 207
17477 Magnesium in the Pathogenesis of Metabolic Disorders_CompressPdf.pdf PDF 2022 admin 23 Apr, 2022 14:56 429.39 Kb 39
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