Loading...
 
Toggle Health Problems and D

COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022


Magnesium-to-Calcium Ratio and Mortality from COVID-19

Nutrients 2022, 14(9), 1686; https://doi.org/10.3390/nu14091686

  • 1 Biomedical Research Unit, Instituto Mexicano del Seguro Social, Durango 34067, Mexico
  • 2 Research Unit in Endocrine Diseases, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico
  • 3 Department of Internal Medicine, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico


Image
This is a subset of the PDF table

Obesity, type 2 diabetes, arterial hypertension, decrease in immune response, cytokine storm, endothelial dysfunction, and arrhythmias, which are frequent in COVID-19 patients, are associated with hypomagnesemia. Given that cellular influx and efflux of magnesium and calcium involve the same transporters, we aimed to evaluate the association of serum magnesium-to-calcium ratio with mortality from severe COVID-19. The clinical and laboratory data of 1064 patients, aged 60.3 ± 15.7 years, and hospitalized by COVID-19 from March 2020 to July 2021 were analyzed. The data of 554 (52%) patients discharged per death were compared with the data of 510 (48%) patients discharged per recovery. The ROC curve showed that the best cut-off point of the magnesium-to-calcium ratio for identifying individuals at high risk of mortality from COVID-19 was 0.20. The sensitivity and specificity were 83% and 24%.
The adjusted multivariate regression model showed that the odds ratio between the magnesium-to-calcium ratio ≤0.20 and discharge per death from COVID-19 was

  • 6.93 (95%CI 1.6–29.1) in the whole population,
  • 4.93 (95%CI 1.4–19.1, p = 0.003) in men, and
  • 3.93 (95%CI 1.6–9.3) in women.
    • ''Suspect a mistake was made: Have not seen an average to be greater thanthe items being averaged''

In conclusion, our results show that a magnesium-to-calcium ratio ≤0.20 is strongly associated with mortality in patients with severe COVID-19.
 Download the PDF from VitaminDWiki


VitaminDWiki - 24 studies in both categories Virus and Magnesium

This list is automatically updated



Created by admin. Last Modification: Saturday November 19, 2022 11:10:12 GMT-0000 by admin. (Version 5)

Attached files

ID Name Comment Uploaded Size Downloads
17455 COVID MgCa.jpg admin 20 Apr, 2022 13:38 71.35 Kb 148
17454 MgCa ratio and COVID.pdf PDF 2022 admin 20 Apr, 2022 13:37 802.41 Kb 49
See any problem with this page? Report it (WORKS NOV 2021)