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500 mg of Magnesium for 8 weeks increased Vitamin D by 4 ng – July 2020

Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain

Nutrients 2020, 12, 2283; doi:10.3390/nu12082283
Héctor Vázquez-Lorente h* , Lourdes Herrera-Quintana , Jorge Molina-López ©, Yenifer Gamarra-Morales h*, Beatriz López-González 1, Claudia Miralles-AdeU 1 and Elena Planells 1

* Correspondence: hectorvazquez at ugr.es (H.V.-L.); jennifer_gamo at hotmail.com (Y.G.-M.)




Menopause is a stage of hormonal imbalance in women which, in addition to other physiopathological consequences, poses a risk of deficiency of key micronutrients such as magnesium and vitamin D. A study was made of the influence of a magnesium intervention upon vitamin D status in a postmenopausal population from the province of Granada (Spain). Fifty-two healthy postmenopausal women between 44-76 years of age were included. Two randomized groups—placebo and magnesium (500 mg/day)—were treated during eight weeks. Nutrient intake was assessed using questionnaires based on 72-h recall. Vitamin D was analyzed by liquid chromatography—tandem mass spectrometry. Baseline vitamin D proved deficient in over 80% of the subjects. The administration of magnesium resulted in significantly increased vitamin D levels in the intervention group versus the controls (p < 0.05). Magnesium supplementation improved vitamin D status in the studied postmenopausal women.
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